Results 181 to 190 of about 150,978 (251)

<i>Gtr9</i> mutation trades phage resistance for carbapenem sensitivity to potentiate phage-meropenem therapy against <i>carbapenem-resistant Acinetobacter baumannii in vitro</i>. [PDF]

Antimicrob Agents Chemother
Luo J, Liu M, Ai W, Zheng X, Han L, Huang K, Zhang C, Fan J, Li Q, Luo C.   +9 more
europepmc   +1 more source

Viruses, Periodontitis, and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte, Yvonne L. Hernandez‐Kapila, Henrik Dommisch   +2 more
wiley   +1 more source

Carbohydrates and the oxidative branch of the pentose phosphate pathway modify <i>Bacteroides thetaiotaomicron</i> phage resistance by phase-variable S-layers. [PDF]

J Bacteriol
Fuentes JJ, Singh S, Pudlo NA, Heaver SL, Ley RE, Martens EC.   +5 more
europepmc   +1 more source

The Dual Face of Fusobacterium nucleatum in Cancer: Foe, Friend or Both?

Journal of Periodontal Research, EarlyView.
Fusobacterium nucleatum has established interactions with cancers in humans. However, contrary to a traditional view that these interactions are uniformly pro‐tumoural, recent evidence suggests a more nuanced role, where contact‐dependent and contact‐independent mechanisms may support either tumour progression or restriction depending on tumour site ...
Anjali Chander, Huile Lim, Gilad Bachrach, Miguel Reis Ferreira   +3 more
wiley   +1 more source

Multi-Omic Analysis of Bacteriophage-Insensitive Mutants Reveals a Putative Role for the Rcs Two-Component Phosphorelay System in Phage Resistance Development in <i>Erwinia amylovora</i>. [PDF]

Viruses
Ibrahim N, Lin JT, Nesbitt D, Tang J, Singh D, Goodridge LD, Lepp D, Svircev AM, Weadge JT, Anany H.   +9 more
europepmc   +1 more source

Periodontal Salutogenesis: Why Are Some People Resistant to Oral Microbial Dysbiosis and Destructive Inflammation?

Journal of Periodontal Research, EarlyView.
Emerging evidence suggests that periodontal health is not simply the absence of disease, but the result of a dynamic interaction between biological resilience, healthy lifestyles, adaptive coping mechanisms, and supportive environments. This results in a strong sense of coherence, which is not only a psychological state but also a biological state ...
Bruno G. Loos, Magda Feres, William V. Giannobile, Hatice Hasturk, Egija Zaura   +4 more
wiley   +1 more source

Augmenting phage therapy using green nanotechnology for promising infection control, wound healing and devoiding phage resistance in MDR Pseudomonas aeruginosa. [PDF]

Sci Rep
Mani A, Shanmugha Mary A, Kalangadan N, Sundaresan S, Ghosh S, Prakash J, Durairajan SSK, Rajaram K.   +7 more
europepmc   +1 more source

The Hna Phage Defence Protein: A DNA‐Stimulated Helicase With Cryptic Nuclease Activity

Molecular Microbiology, EarlyView.
The Hna (Helicase‐nuclease Abi) phage defence system consists of a single protein and provides defence through abortive infection. We show that Hna's abortive infection response can be recreated in a heterologous host upon expression of phage single‐stranded DNA binding protein (SSB) and present a characterization of Hna's biochemical activity.
Leah M. Sather, Maryam Zamani, Sara N. Andres, Turlough M. Finan   +3 more
wiley   +1 more source

Type IV‐Dominated Plasmid‐Encoded CRISPR‐Cas Systems Are Enriched in Multireplicon and Multi‐Stressor Resistance Plasmids Across the Global Plasmidome

Molecular Microbiology, EarlyView.
Screening 72,555 plasmid sequences reveals that intact CRISPR‐Cas systems are rare (1.03%) but strongly enriched in multireplicon and multi‐stressor resistance plasmids, with Type IV‐A as the dominant subtype. These findings implicate plasmid‐encoded CRISPR‐Cas as non‐randomly retained elements of structurally complex and high‐risk backbones.
Hannay Crystynah Almeida de Souza, Anamaria Mota Pereira dos Santos, Arlen Carvalho de Oliveira Almeida, Carlos Adam Conte Junior, Pedro Panzenhagen   +4 more
wiley   +1 more source

Exploring phage-host interactions in <i>Burkholderia cepacia</i> complex bacterium to reveal host factors and phage resistance genes using CRISPRi functional genomics and transcriptomics. [PDF]

Microbiol Spectr
Diaz B, Krishna R, Schoeniger JS, Mageeney CM.   +3 more
europepmc   +1 more source