Development of Phage Cocktails to Treat E. coli Catheter-Associated Urinary Tract Infection and Associated Biofilms [PDF]
Frontiers in Microbiology, 2022 High rates of antimicrobial resistance and formation of biofilms makes treatment of Escherichia coli catheter-associated urinary tract infections (CAUTI) particularly challenging.
Belkys C. Sanchez +15 more
doaj +3 more sources
Efficacy of Lytic Phage Cocktails on Staphylococcus aureus and Pseudomonas aeruginosa in Mixed-Species Planktonic Cultures and Biofilms [PDF]
Viruses, 2020 The efficacy of phages in multispecies infections has been poorly examined. The in vitro lytic efficacies of phage cocktails AB-SA01, AB-PA01, which target Staphylococcus aureus and Pseudomonas aeruginosa, respectively, and their combination against ...
Legesse Garedew Kifelew +6 more
doaj +3 more sources
A Novel Method to Create Efficient Phage Cocktails via Use of Phage-Resistant Bacteria. [PDF]
Appl Environ Microbiol, 2022 The rapid antiphage mutation of pathogens is a big challenge often encountered in phage therapy. Using a cocktail composed of phages with different infection strategies can better overcome this problem.
Li C, Shi T, Sun Y, Zhang Y.
europepmc +4 more sources
Phage cocktails and the future of phage therapy.
Future Microbiology, 2013 Viruses of bacteria, known as bacteriophages or phages, were discovered nearly 100 years ago. Their potential as antibacterial agents was appreciated almost immediately, with the first 'phage therapy' trials predating Fleming's discovery of penicillin by
B. Chan, S. Abedon, C. Loc-Carrillo
semanticscholar +5 more sources
Computer Methods and Programs in Biomedicine, 2022 BACKGROUND AND OBJECTIVE Phage therapy is a resurgent strategy used in medicine and the food industry to lyse bacteria that cause damage to health or spoil a food product.
M. V. Díaz-Galián +2 more
semanticscholar +5 more sources
Computational Basis for On-Demand Production of Diversified Therapeutic Phage Cocktails. [PDF]
mSystems, 2020 The antibiotic resistance crisis has led to renewed interest in phage therapy as an alternative means of treating infection. However, conventional methods for isolating pathogen-specific phage are slow, labor-intensive, and frequently unsuccessful.
Mageeney CM +8 more
europepmc +7 more sources
Tailoring Effective Phage Cocktails for Long-Term Lysis of Escherichia coli Based on Physiological Properties of Constituent Phages. [PDF]
Phage (New Rochelle), 2023 Background: Bacteriophage (phage) therapy has regained attention as an alternative to antimicrobial agents for eliminating bacteria; however, the emergence of phage-resistant bacteria during the therapy is a major concern.
Kaneko T, Osaka T, Tsuneda S.
europepmc +2 more sources
Paenibacillus larvae and their phages; a community science approach to discovery and initial testing of prophylactic phage cocktails against American Foulbrood in New Zealand. [PDF]
Microbiome Res Rep, 2023 Background: American foulbrood (AFB) is a devastating disease of the European honey bee (Apis mellifera) and is found throughout the world. AFB is caused by the bacterium Paenibacillus larvae (P. larvae).
Kok DN +3 more
europepmc +2 more sources
Phage cocktails: state-of-the-art technologies and strategies for effective design. [PDF]
FEMS Microbiol RevWith the growing severity of antimicrobial resistance (AMR), phage therapy has garnered attention as a novel therapeutic alternative. In particular, phage cocktails, which combine multiple phages, potentially offer broader antimicrobial spectra than ...
Kaneko T, Nakatsuka K, Tsuneda S.
europepmc +2 more sources
Deploying Viruses against Phytobacteria: Potential Use of Phage Cocktails as a Multifaceted Approach to Combat Resistant Bacterial Plant Pathogens. [PDF]
Viruses, 2022 Plants in nature are under the persistent intimidation of severe microbial diseases, threatening a sustainable food production system. Plant-bacterial pathogens are a major concern in the contemporary era, resulting in reduced plant growth and ...
Farooq T +9 more
europepmc +2 more sources