Metagenomic Analysis of Therapeutic PYO Phage Cocktails from 1997 to 2014 [PDF]
Viruses, 2017 Phage therapy has regained interest in recent years due to the alarming spread of antibiotic resistance. Whilst phage cocktails are commonly sold in pharmacies in countries such as Georgia and Russia, this is not the case in western countries due to ...
Julia Villarroel +3 more
doaj +15 more sources
Systematic analysis of putative phage-phage interactions on minimum-sized phage cocktails [PDF]
Scientific Reports, 2022 The application of bacteriophages as antibacterial agents has many benefits in the “post-antibiotic age”. To increase the number of successfully targeted bacterial strains, phage cocktails, instead of a single phage, are commonly formulated. Nevertheless,
Felipe Molina +4 more
doaj +9 more sources
Comparison of bacterial suppression by phage cocktails, dual‐receptor generalists, and coevolutionarily trained phages [PDF]
Evolutionary Applications, 2023 The evolution and spread of antibiotic‐resistant bacteria have renewed interest in phage therapy, the use of bacterial viruses (phages) to combat bacterial infections.
Joshua M. Borin +3 more
doaj +7 more sources
In Vitro Design and Evaluation of Phage Cocktails Against Aeromonas salmonicida [PDF]
Frontiers in Microbiology, 2018 As an alternative approach against multidrug-resistant bacterial infections, phages are now being increasingly investigated as effective therapeutic agents.
Ling Chen +9 more
doaj +8 more sources
Phage Cocktails Constrain the Growth of Enterococcus [PDF]
mSystems, 2022 Phages that infect pathogenic bacteria present a valuable resource for treating antibiotic-resistant infections. We isolated and developed a collection of 19 Enterococcus phages, including myoviruses, siphoviruses, and a podovirus, that can infect both ...
Stephen Wandro +8 more
doaj +7 more sources
A mechanism-based pathway toward administering highly active N-phage cocktails. [PDF]
Front Microbiol, 2023 Bacteriophage (phage) therapy is being explored as a possible response to the antimicrobial resistance public health emergency. Administering a mixture of different phage types as a cocktail is one proposed strategy for therapeutic applications, but the ...
Smith NM +7 more
europepmc +7 more sources
A New Pipeline for Designing Phage Cocktails Based on Phage-Bacteria Infection Networks. [PDF]
Front Microbiol, 2021 In recent years, the spread of antibiotic-resistant bacteria and efforts to preserve food microbiota have induced renewed interest in phage therapy. Phage cocktails, instead of a single phage, are commonly used as antibacterial agents since the hosts are
Molina F +5 more
europepmc +8 more sources
Designing phage cocktails to combat the emergence of bacteriophage-resistant mutants in multidrug-resistant Klebsiella pneumoniae [PDF]
Microbiology Spectrum, 2023 Phage therapy, an emerging strategy in the fight against recalcitrant bacterial infections, encounters a significant hurdle posed by the development of phage-resistant bacterial strains. To address this concern, we suggest a novel phage cocktail.
Seongjun Yoo +5 more
doaj +3 more sources
Formulation of phage cocktails and evaluation of their interaction with antibiotics in inhibiting carbapenemase-producing Klebsiella pneumoniae in vitro in Kenya [PDF]
African Journal of Laboratory Medicine, 2022 Background: The development of alternative control measures, such as phage therapy or adjunctive therapy, is urgently needed to manage the dissemination of carbapenemase-producing Klebsiella pneumoniae.
Noutin F. Michodigni +5 more
doaj +3 more sources
Antibacterial effect of phage cocktails and phage-antibiotic synergy against pathogenic Klebsiella pneumoniae. [PDF]
mSystemsThe global rise of antibiotic resistance has renewed interest in phage therapy, as an alternative to antibiotics to eliminate multidrug-resistant (MDR) bacterial pathogens.
Zhao M +5 more
europepmc +5 more sources