Results 31 to 40 of about 367 (86)
Gut virome orchestrates nitrogen partitioning between the host and microbiome
iMeta, EarlyView.Under normal protein intake, lytic phages promote bacterial turnover, releasing microbial nitrogen that can be assimilated by the host and thereby revealing phage‐mediated lysis as a potential pathway for host nutrient acquisition. Under protein restriction, however, phages shift toward a lysogenic strategy, reducing bacterial death and microbial ...
Shujie Xu +7 more
wiley +1 more source
Phage cocktail strategies for the suppression of a pathogen in a cross‐feeding coculture
Microbial Biotechnology, 2020 Summary Cocktail combinations of bacteria‐infecting viruses (bacteriophages) can suppress pathogenic bacterial growth. However, predicting how phage cocktails influence microbial communities with complex ecological interactions, specifically cross ...
Lisa Fazzino +3 more
doaj +1 more source
Anti-Biofilm Effect of Bacteriophages and Antibiotics against Uropathogenic Escherichia coli
Antibiotics, 2022 Escherichia coli is a common cause of biofilm-associated urinary tract infections. Bacteria inside the biofilm are more resistant to antibiotics. Six E.
Laima Mukane +4 more
doaj +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Directed in Vitro Evolution of Therapeutic Bacteriophages: The Appelmans Protocol
Viruses, 2019 The ‘Appelmans protocol’ is used by Eastern European researchers to generate therapeutic phages with novel lytic host ranges. Phage cocktails are iteratively grown on a suite of mostly refractory bacterial isolates until the evolved cocktail ...
Ben H. Burrowes +2 more
doaj +1 more source
Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies
Medicinal Research Reviews, EarlyView.ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva +23 more
wiley +1 more source
Microbiology SpectrumMultidrug-resistant (MDR) Pseudomonas aeruginosa poses a significant global health threat, necessitating alternative therapeutic strategies. Bacteriophage therapy shows promise, but single-phage use is prone to resistance.
Meshack Tweya Omwega +8 more
doaj +1 more source
Programmable Assembly of Higher‐Order DNA Nanostructures from Microbial ssDNA Staple Libraries
Small, EarlyView.A phage‐free, microbial platform produces programmable circular ssDNA libraries that are enzymatically converted into DNA origami staple pools. Rolling‐circle replication generates sequence‐complex ssDNA with >99% fidelity, enabling assembly of DNA tiles and tubules and supporting nanostructure formation even in crude cellular lysates.
Ming Hung Yen +4 more
wiley +1 more source
VIEW, EarlyView.Periodontal homeostasis is maintained by coordinated interactions between the oral microbiome and host. Dysbiosis disrupts this ecological balance and contributes to periodontal disease, whereas multi‐omics, artificial intelligence, and microbiome‐based interventions provide emerging opportunities for precision diagnosis, ecological restoration, and ...
Xu Liu +11 more
wiley +1 more source
Synergy as a rationale for phage therapy using phage cocktails [PDF]
PeerJ, 2014 Where phages are used to treat bacterial contaminations and infections, multiple phages are typically applied at once as a cocktail. When two or more phages in the cocktail attack the same bacterium, the combination may produce better killing than any ...
Matthew Schmerer +2 more
doaj +2 more sources