Results 51 to 60 of about 64,822 (118)

Identification of Structural Proteins of Rhizobium meliloti Temperate Phage 16-3 [PDF]

, 1982
The structural proteins of Rhizobium meliloti temperate phage 16-3 have been analysed by means of polyacrylamide gel electrophoresis, isoelectric focusing and agarose gel electrophoresis.
Dudás, Brigitta, Erdei, Sára, Duda, Ernő, Orosz, László   +3 more
core   +1 more source

Gut virome orchestrates nitrogen partitioning between the host and microbiome

iMeta, EarlyView.
Under normal protein intake, lytic phages promote bacterial turnover, releasing microbial nitrogen that can be assimilated by the host and thereby revealing phage‐mediated lysis as a potential pathway for host nutrient acquisition. Under protein restriction, however, phages shift toward a lysogenic strategy, reducing bacterial death and microbial ...
Shujie Xu, Xianglin Fei, Fengqing Lin, Wenzi Wu, Jiachen Zhuang, Qiufen Mo, Xiuan Zhan, Aikun Fu   +7 more
wiley   +1 more source

Phenotypic heterogeneity shapes phage resistance and cocktail efficacy in Klebsiella pneumoniae

Microbiology Spectrum
The emergence of phage-resistant bacteria poses a significant challenge to the success of phage therapy. Although phage cocktails can delay resistance, their efficacy relies on the ability to target the full spectrum of resistant variants, which are ...
Lucas Mora-Quilis, Rafael Sanjuán, Pilar Domingo-Calap   +2 more
doaj   +1 more source

Metagenome analysis of Russian and Georgian Pyophage cocktails and a placebo-controlled safety trial of single phage versus phage cocktail in healthy Staphylococcus aureus carriers

, 2018
Bacteriophage therapy is a commonly used treatment for Staphylococcus aureus infections in countries of the former Soviet Union, using both single phages and phage cocktails.
Oechslin, Frank, Sultana, S., Sultana, Shamima, Bruessow, Harald, Brüssow, H., Sarker, Shafiqul A., Sarker, S.A., McCallin, S., Oechslin, F., McCallin, Shawna   +9 more
core   +1 more source

inPhocus: Current State and Challenges of Phage Research in Singapore.

, 2023
Bacteriophages and phage-derived proteins are a promising class of antibacterial agents that experience a growing worldwide interest. To map ongoing phage research in Singapore and neighboring countries, Lee Kong Chian School of Medicine, Nanyang ...
Kwa, AL-H, Hariharan, S, Chung, SJ, Goh, BC, Paul, VD, Verma, NK, Ostrowski, A, Lakshminarayanan, R, Sriram, B, Chen, J, Clokie, MRJ, Sicheritz-Pontén, T, Rice, SA, Dam, LC, Chan, CC, Goh, KCM, Aung, TT, Chen, H, Bifani, P, Razali, H, Gautam, HK, Thong, SH, Ismail, MH, Bhattacharyya, MS, van Steensel, MAM, Low, SWY, Tan, SJ, Ho, P, Moreira, W   +28 more
core   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Phage cocktail strategies for the suppression of a pathogen in a cross‐feeding coculture

Microbial Biotechnology, 2020
Summary Cocktail combinations of bacteria‐infecting viruses (bacteriophages) can suppress pathogenic bacterial growth. However, predicting how phage cocktails influence microbial communities with complex ecological interactions, specifically cross ...
Lisa Fazzino, Jeremy Anisman, Jeremy M. Chacón, William R. Harcombe   +3 more
doaj   +1 more source

Anti-Biofilm Effect of Bacteriophages and Antibiotics against Uropathogenic Escherichia coli

Antibiotics, 2022
Escherichia coli is a common cause of biofilm-associated urinary tract infections. Bacteria inside the biofilm are more resistant to antibiotics. Six E.
Laima Mukane, Karlis Racenis, Dace Rezevska, Aivars Petersons, Juta Kroica   +4 more
doaj   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Directed in Vitro Evolution of Therapeutic Bacteriophages: The Appelmans Protocol

Viruses, 2019
The ‘Appelmans protocol’ is used by Eastern European researchers to generate therapeutic phages with novel lytic host ranges. Phage cocktails are iteratively grown on a suite of mostly refractory bacterial isolates until the evolved cocktail ...
Ben H. Burrowes, Ian J. Molineux, Joe A. Fralick   +2 more
doaj   +1 more source