Results 41 to 50 of about 367 (86)
Synergy as a rationale for phage therapy using phage cocktails [PDF]
PeerJ, 2014 Where phages are used to treat bacterial contaminations and infections, multiple phages are typically applied at once as a cocktail. When two or more phages in the cocktail attack the same bacterium, the combination may produce better killing than any ...
Matthew Schmerer +2 more
doaj +2 more sources
Transgenic selection and underlying mechanisms in apicomplexan parasites
The FEBS Journal, EarlyView.Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju +2 more
wiley +1 more source
The FEBS Journal, EarlyView.Bacteriophages—viruses that kill bacteria—are promising weapons against bacterial biofilms: sessile communities notoriously resistant to antibiotics. Yet phages evolved not so much to eradicate bacteria as to obtain new bacteria to infect. That goal, however, may conflict with the physician's objective of complete bacterial clearance.
Stephen T. Abedon
wiley +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Agrobacterium tumefaciens is a powerful delivery tool for plant genetic transformation and a pivotal platform for agricultural biotechnology. However, laboratory strains of Agrobacterium have remained genetically unoptimized for decades, with genome engineering hindered by inefficient, endogenous homologous recombination systems.
Minmin Zheng +4 more
wiley +1 more source
Phage Cocktails for Biological Decontamination: A Narrative Review of Applications, Formulation Challenges, and Translational Barriers [PDF]
Journal of Mazandaran University of Medical SciencesBackground and purpose: Healthcare-associated infections and the increasing prevalence of antimicrobial resistance are among the most critical global public health challenges.
Golnar Rahimzadeh, Mohammad Sadegh Rezai
doaj
Novel and emerging antimicrobial strategies in the management of oral infections
Periodontology 2000, EarlyView.Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley +1 more source
MethodsXSpot overlay assays are a common method for measuring phage activity against target microorganisms and determining % host range activity. Dilutions of phage demonstrate activity by creating a zone of clearing indicative of bacterial killing; however ...
Steven Arcidiacono, Robert Stote
doaj +1 more source
Aquaculture, Fish and Fisheries, Volume 6, Issue 5, October 2026.Pathogenesis of bacterial diseases in Nile tilapia and anti‐bacterial mechanisms. ABSTRACT Nile tilapia (Oreochromis niloticus) is among the most widely farmed fish globally that plays a major role in ensuring food security in many low‐ and middle‐income countries.
Catherine Agoe +8 more
wiley +1 more source
Advanced NanoBiomed Research, Volume 6, Issue 10, October 2026.Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi +6 more
wiley +1 more source
Multi-strain phage induced clearance of bacterial infections.
PLoS Computational BiologyBacteriophage (or 'phage' - viruses that infect and kill bacteria) are increasingly considered as a therapeutic alternative to treat antibiotic-resistant bacterial infections.
Jacopo Marchi +3 more
doaj +1 more source