In Fungal Intracellular Pathogenesis, Form Determines Fate
mBio, 2018 For pathogenic microbes to survive ingestion by macrophages, they must subvert powerful microbicidal mechanisms within the phagolysosome. After ingestion, Candida albicans undergoes a morphological transition producing hyphae, while the surrounding ...
Robin C. May, Arturo Casadevall
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The unusual microtubule polarity in teleost retinal pigment epithelial cells. [PDF]
, 1988 In cells of the teleost retinal pigment epithelium (RPE), melanin granules disperse into the RPE cells long apical projections in response to light onset, and aggregate toward the base of the RPE cell in response to dark onset.
BURNSIDE, Beth, Troutt, L
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The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations
Acta Paediatrica, EarlyView.ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
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Heat Shock Protein Magic in Antigen Trafficking within Dendritic Cells:Implications in Antigen Cross-presentation in Immunity [PDF]
, 2012 Dendritic cells (DCs) take up soluble- or cell-associated antigens and digest them, delivering fragments to the MHC class I pathway to display antigenic peptides to CD8＋ T cells, a process known as cross-presentation.
Udono, Heiichiro
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Lung organoids as a human system for Mycobacteria infection modeling and drug testing
The FEBS Journal, EarlyView.Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza +4 more
wiley +1 more source
The FEBS Journal, EarlyView.We describe the CD9 interactome in epithelial cells for the first time. The interactome is diverse and dynamic and changes dependent on infection with specific bacteria. We validate these data by showing functional interaction between CD9 with CD44 or CD147. We therefore demonstrate that CD9 is a universal organiser of bacterial adhesion platforms able
Paige A. Wolverson +5 more
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Two distinct penicillin binding proteins promote cell division in different Salmonella lifestyles
Microbial Cell, 2018 The bacterial cell wall preserves cell integrity in response to external insults and the internal turgor pressure. The major component of the cell wall is the peptidoglycan (PG); a giant macromolecule formed by glycan chains cross-linked by short ...
Sónia Castanheira +3 more
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Delay of phagosome maturation by a mycobacterial lipid is reversed by nitric oxide.
, 2008 Mycobacterium tuberculosis is a facultative intracellular pathogen that inhibits phagosome maturation in macrophages thereby securing survival and growth.
Axelrod, Sofia +7 more
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Reply to "Unrealistic nonphysiological amounts of reagents and a disregard for published literature" [PDF]
, 2015 Peer reviewedPublisher ...
Brown, Alistair J P
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The extraordinary phagosome [PDF]
Nature, 2002 The finding that a cellular compartment called the endoplasmic reticulum can merge with the cell's outer membrane is surprising. It would not have been predicted from our knowledge of cell organization.
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