Results 111 to 120 of about 50,774 (237)
Journal of Fish Diseases, EarlyView.ABSTRACT Host–parasite interactions are influenced by both abiotic and biotic factors. While abiotic drivers, particularly temperature, have received considerable attention in recent years due to global climate change, the role of biotic factors remains comparatively underexplored.
Lauri Saks +4 more
wiley +1 more source
Microtubule motors transport phagosomes in the RPE, and lack of KLC1 leads to AMD-like pathogenesis. [PDF]
, 2015 The degradation of phagosomes, derived from the ingestion of photoreceptor outer segment (POS) disk membranes, is a major role of the retinal pigment epithelium (RPE). Here, POS phagosomes were observed to associate with myosin-7a, and then kinesin-1, as
Diemer, Tanja +6 more
core +1 more source
The Role of Oxidative Stress in Periodontitis
Journal of Periodontal Research, EarlyView.Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon +3 more
wiley +1 more source
PLoS ONE, 2014 Tropheryma whipplei, the agent of Whipple's disease, inhibits phago-lysosome biogenesis to create a suitable niche for its survival and replication in macrophages. To understand the mechanism by which it subverts phagosome maturation, we used biochemical
Giovanna Mottola +6 more
doaj +1 more source
RNA interference screening reveals host CaMK4 as a regulator of cryptococcal uptake and pathogenesis [PDF]
, 2017 Cryptococcus neoformans , the causative agent of cryptococcosis, is an opportunistic fungal pathogen that kills over 200,000 individuals annually. This yeast may grow freely in body fluids, but it also flourishes within host cells.
Doering, Tamara L +4 more
core +2 more sources
Molecular Microbiology, EarlyView.Human macrophage transcriptomic responses to Mycobacterium avium (Mav), a major cause of nontuberculous lung disease, were compared to Mycobacterium tuberculosis (Mtb). Both infections activated overlapping immune pathways, including cytokine signaling and GPCRs involved in lipid metabolism, while phospholipases were more strongly regulated by Mav and ...
Gül Kilinç +4 more
wiley +1 more source
Towards understanding the antibacterial activity of Ag nanoparticles: electron microscopy in the analysis of the materials-biology interface in the lung [PDF]
, 2015 Bacterial infections of the pulmonary system are increasing.
leo, BF +4 more
core +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Citrus Huanglongbing (HLB), a devastating disease caused by the unculturable bacterium ‘Candidatus Liberibacter asiaticus’ (CLas), poses a severe threat to global citrus production. CLas secretes effectors to suppress host immune responses and facilitate its colonisation. Previously, the CLas effector SECP8 (CLIBASIA_05330) has been identified
Mingyue Qin +8 more
wiley +1 more source
Defective phagocytic corpse processing results in neurodegeneration and can be rescued by TORC1 activation [PDF]
, 2016 This work was supported by NIH Grants R01 GM094452 (K.M.) and F31 GM099425 (J.I.E.), BU Alzheimer's Disease Core Center NIH Grant P30 AG13846, Boston University Undergraduate Research Opportunities Program grants (J.A.T., V.S.), and NIH Grant R01 ...
Elguero, Emma J. +5 more
core +1 more source
Histiocytes: Multifaceted Regulators of Health and Disease
Veterinary Clinical Pathology, EarlyView.ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley +1 more source