Results 51 to 60 of about 36,298 (238)

The Formation and Renewal of Photoreceptor Outer Segments

open access: yesCells
The visual system is essential for humans to perceive the environment. In the retina, rod and cone photoreceptor neurons are the initial sites where vision forms.
Jingjin Xu, Chengtian Zhao, Yunsi Kang
doaj   +1 more source

Frustrated phagocytosis on micro-patterned immune complexes to characterize lysosome movements in live macrophages.

open access: yesFrontiers in Immunology, 2011
Lysosome mobilization is a key cellular process in phagocytes for bactericidal activities and trans-matrix migration. The molecular mechanisms that regulate lysosome mobilization are still poorly known.
Arnaud M. Labrousse   +8 more
doaj   +1 more source

Anisotropic presentation of ligands on cargos modulates degradative function of phagosomes

open access: yesBiophysical Reports, 2022
Anisotropic arrangement of cell wall components is ubiquitous among bacteria and fungi, but how such functional anisotropy affects interactions between microbes and host immune cells is not known.
Mengchi Jiao   +3 more
doaj   +1 more source

Dysfunctional Light-Evoked Regulation of cAMP in Photoreceptors and Abnormal Retinal Adaptation in Mice Lacking Dopamine D4 Receptors [PDF]

open access: yes, 2002
Dopamine is a retinal neuromodulator that has been implicated in many aspects of retinal physiology. Photoreceptor cells express dopamine D4 receptors that regulate cAMP metabolism.
Grandy, David K.   +6 more
core   +1 more source

Kinetic studies of Candida parapsilosis phagocytosis by macrophages and detection of intracellular survival mechanisms [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
Alonso, Maria F   +8 more
core   +4 more sources

The Mycobacterium tuberculosis Phagosome [PDF]

open access: yes, 2008
Tuberculosis is currently the most devastating human bacterial disease, causing millions of deaths annually and infecting an overwhelming percentage of the global population. Its success as a scourge lies in the ability of Mycobacterium tuberculosis to prevent normal phagolysosome biogenesis, essential to the destruction of invading microorganisms ...
Esteban A, Roberts, Vojo, Deretic
openaire   +2 more sources

Redox-sensitive probes for the measurement of redox chemistries within phagosomes of macrophages and dendritic cells

open access: yesRedox Biology, 2013
There is currently much interest in factors that affect redox chemistries within phagosomes of macrophages and dendritic cells. In addition to the antimicrobial role of reactive oxygen species generation within phagosomes, accumulating evidence suggests ...
Dale R. Balce, Robin M. Yates
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Mechanism of inducible nitric oxide synthase exclusion from mycobacterial phagosomes.

open access: yesPLoS Pathogens, 2007
Mycobacterium tuberculosis is sensitive to nitric oxide generated by inducible nitric oxide synthase (iNOS). Consequently, to ensure its survival in macrophages, M. tuberculosis inhibits iNOS recruitment to its phagosome by an unknown mechanism.
Alexander S Davis   +5 more
doaj   +1 more source

Phagosome-lysosome fusion is a calcium-independent event in macrophages. [PDF]

open access: yes, 1996
Phagosome-lysosome membrane fusion is a highly regulated event that is essential for intracellular killing of microorganisms. Functionally, it represents a form of polarized regulated secretion, which is classically dependent on increases in ...
Ernst, JD   +5 more
core   +2 more sources

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