Results 41 to 50 of about 76,692 (224)

Old School Catalog 1921-22, The School of Pharmacy [PDF]

, 1921
https://scholar.valpo.edu/oldschoolcatalogs/1089/thumbnail ...
Valparaiso University
core   +2 more sources

D‐glucuronyl C5‐Epimerase Binds to EGFR to Suppress Kidney Fibrosis

Advanced Science, EarlyView.
Glucuronyl C5‐epimerase (Hsepi, gene name Glce) is a key enzyme catalyzing heparan sulfate (HS) chain biosynthesis in HS proteoglycans, which are ubiquitously expressed on cell membranes. In normal renal tubular cells, Glce binds to the intracellular domains of EGFR, maintaining stable and orderly EGFR phosphorylation.
Xiaoqi Jing, Jun Wu, Jingru Ning, Xiaoyu Ding, Zhenyun Du, Xiaojiang Wang, Lulin Huang, Ran Wang, Changlin Mei, Kan Ding   +9 more
wiley   +1 more source

Old School Catalog 1911-12, Chicago College of Medicine and Surgery [PDF]

, 1911
https://scholar.valpo.edu/oldschoolcatalogs/1015/thumbnail ...
Valparaiso University
core   +2 more sources

Cinobufagin Directly Targets PDE4D to Disrupt Fibroblast–Dendritic Cell Crosstalk in Atopic Dermatitis

Advanced Science, EarlyView.
Single‐cell RNA sequencing revealed that MIF signaling drives inflammatory fibroblastmyeloid cell crosstalk in atopic dermatitis. Cinobufagin, a potent PDE4D inhibitor, suppresses MIF and reduces inflammation by restoring the cAMP/PKA/CREB pathway. Genetic knockout validates PDE4D as a key driver and promising therapeutic target for atopic dermatitis ...
Shicong Li, Dihui Xu, Chenyang Zhang, Chunxiu Xiao, Meng Yu, Jiaojiao Wang, Wenyuan Wu, Xiang Lv, Dongping Yuan, Liang Zhang, Min Hong, Jing Zhou, Yang Sun, Hongyue Ma, Yuyu Zhu   +14 more
wiley   +1 more source

Synthesis and Biological Evaluation of Ginsenoside Compound K Derivatives as a Novel Class of LXRα Activator

Molecules, 2017
Compound K is one of the active metabolites of Panaxnotoginseng saponins, which could attenuate the formation of atherosclerosis in mice modelsvia activating LXRα.
Yan Huang, Hongmei Liu, Yingxian Zhang, Jin Li, Chenping Wang, Li Zhou, Yi Jia, Xiaohui Li   +7 more
doaj   +1 more source

Old School Catalog 1909-10, Chicago College of Medicine and Surgery [PDF]

, 1909
https://scholar.valpo.edu/oldschoolcatalogs/1019/thumbnail ...
Valparaiso University
core   +1 more source

GLS1‐RNA Polymerase II Axis Mediates Glutamine‐Dependent Hepatoprotective Effects on Alcoholic Liver Disease in High‐Protein Diets

Advanced Science, EarlyView.
GLS1 interacts with RNA polymerase II subunits, ROLR2H and POLR2E, resulting in significant suppression of RNA polymerase II activity. Importantly, the investigation demonstrates that high‐protein diets, particularly glutamine, exert protective effects against alcoholic fatty liver through GLS1‐RNA polymerase II axis.
Wenbiao Wu, Haowen Jiang, Yichang Liu, Chang Peng, Hanlin Wang, Wenhua Yang, Zan Lyu, Yan Sun, Huan Ma, Hongyu Gu, Weijuan Kan, Liya Jing, Tiancheng Dong, Chunmei Xia, Saifei Lei, Rui Wu, Jinlong Li, Jia Li   +17 more
wiley   +1 more source

Based on Systematic Pharmacology: Molecular Mechanism of Siwei Jianbu Decoction in Preventing Oxaliplatin-Induced Peripheral Neuropathy

Neural Plasticity, 2020
Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting side effect caused by chemotherapy drugs, and its existence seriously affects the quality of life of patients.
Peng Zhang, Yuting Lu, Chao Yang, Qiuyan Zhang, Yangyan Qian, Jinshuai Suo, Peng Cheng, Jing Zhu   +7 more
doaj   +1 more source

Garuda 5 (khyung lnga): Ecologies of Potency and the Poison-Medicine Spectrum of Sowa Rigpa’s Renowned ‘Black Aconite’ Formula [PDF]

, 2019
This article focuses on ethnographic work conducted at the Men-Tsee-Khang (Dharamsala, India) on Garuda 5 (khyung lnga), a commonly prescribed Tibetan medical formula.
van der Valk, Jan M. A.
core   +1 more source

Medical Science of Milk Included in Celsus’ Treatise De medicina [PDF]

, 2016
Milk was a very significant food product in the Mediterranean. The present study is not devoted to milk as such, but to therapeutic galactology, galaktologia iatrike (γαλακτολογία ἰατρική), a version of which is extant in De medicina penned by a Roman ...
Dybała, Jolanta, Kokoszko, Maciej
core   +1 more source