Results 31 to 40 of about 965,054 (258)

Variational models for phase separation

Interfaces and Free Boundaries, Mathematical Analysis, Computation and Applications, 2003
The paper is concerned with the asymptotic behaviour of a family of integral functionals connected with classical models for phase separation. Let \(W\) be a nonnegative, continuous, double well type energy density with minima located at \(u=0\) and \(u=1\), and with linear growth at infinity.
VITALI, ENRICO, SOLCI, MARGHERITA
openaire   +4 more sources

Genomic variability of lipooligosaccharide biosynthesis locus and sequence type among Campylobacter jejuni isolated from patients with Guillain-Barré syndrome

Microbiology Spectrum
Lipooligosaccharide (LOS) is a crucial component of the Campylobacter jejuni (C. jejuni) cell membrane that mimics human gangliosides and can induce autoimmune neuropathies like Guillain-Barré syndrome (GBS). Approximately one in 1,000 C.
Md. Abu Jaher Nayeem, Shoma Hayat, Asaduzzaman Asad, Md. Golam Mostafa, Shah Nayeem Faruque, Ruma Begum, Mosabbir Ahmed, Yearul Kabir, Israt Jahan, Zhahirul Islam   +9 more
doaj   +1 more source

Phasevarions in Haemophilus influenzae biogroup aegyptius control expression of multiple proteins

Microbiology Spectrum
Haemophilus influenzae biogroup aegyptius is the causative agent of Brazilian purpuric fever (BPF), an invasive disease with high mortality, that sporadically manifests in children previously suffering conjunctivitis. Though strains of H.
Greg Tram, Freda E.-C. Jen, Zachary N. Phillips, John F. Lancashire, Jamie Timms, Jessica Poole, Michael P. Jennings, John M. Atack   +7 more
doaj   +1 more source

Helicobacter pylori glycan biosynthesis modulates host immune cell recognition and response

Frontiers in Cellular and Infection Microbiology
IntroductionThe pathogenic bacterium Helicobacter pylori has evolved glycan-mediated mechanisms to evade host immune defenses. This study tests the hypothesis that genetic disruption of H. pylori glycan biosynthesis alters immune recognition and response
Katharine A. Barrett, Francis Jacob Kassama, William Surks, Andrew J. Mulholland, Karen D. Moulton, Danielle H. Dube   +5 more
doaj   +1 more source

Multiple Regulatory Mechanisms Control the Production of CmrRST, an Atypical Signal Transduction System in Clostridioides difficile

mBio, 2022
Clostridioides difficile, an intestinal pathogen and leading cause of nosocomial infection, exhibits extensive phenotypic heterogeneity through phase variation.
Elizabeth M. Garrett, Anchal Mehra, Ognjen Sekulovic, Rita Tamayo   +3 more
doaj   +1 more source

Plasmids and phase variation in Xenorhabdus spp [PDF]

Applied and Environmental Microbiology, 1991
Three strains of Xenorhabdus nematophilus (A24, F1, NC116) and strain Dan of Xenorhabdus bovienii were tested to evaluate whether the phase variation observed in these bacteria was in any way connected with plasmids. The plasmid patterns of both phases of A24 and F1 strains were the same, whereas the two NC116 phases had only one band each.
Leclerc, M.C., Boemare, N.E.
openaire   +3 more sources

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

High-throughput phenotype-to-genotype testing of meningococcal carriage and disease isolates detects genetic determinants of disease-relevant phenotypic traits

mBio
Genome-wide association studies (GWAS) with binary or single phenotype data have successfully identified disease-associated genotypes and determinants of antimicrobial resistance.
Robeena Farzand, Mercy W. Kimani, Evangelos Mourkas, Abdullahi Jama, Jack L. Clark, Megan De Ste Croix, William M. Monteith, Jay Lucidarme, Neil J. Oldfield, David P. J. Turner, Ray Borrow, Luisa Martinez-Pomares, Samuel K. Sheppard, Christopher D. Bayliss   +13 more
doaj   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

A Type III restriction–modification system in Mycoplasma mycoides subsp. capri [PDF]

Open Biology, 2012
The sequenced genome of Mycoplasma mycoides subsp. capri revealed the presence of a Type III restriction–modification system (MmyCI). The methyltransferase (modification) subunit of MmyCI (M.MmyCI) was shown to recognize the sequence 5′-TGAG-3′ and ...
Mikkel A. Algire, Michael G. Montague, Sanjay Vashee, Carole Lartigue, Chuck Merryman   +4 more
doaj   +1 more source