Results 71 to 80 of about 9,767 (219)

EVALUATION OF COCAINE SAMPLES SEIZED IN THE STREETS OF THE STATE OF RIO DE JANEIRO, BRAZIL

open access: yesQuímica Nova
Fifty-two samples of street cocaine seized in the state of Rio de Janeiro, from May 2016 to April 2017, were evaluated according to their purity, presence of inorganic and sugar diluents and concentration of pharmacologically active adulterants.
Luiza D. Sant'Ana   +6 more
doaj   +1 more source

Differences in mRNA Expression of Selected Cytochrome P450, Transporters and Nuclear Receptors Among Various Rat Models of Metabolic Syndrome

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 137, Issue 2, August 2025.
Metabolic syndrome (MetS) is a combination of several factors, which lead to a higher risk of cardiovascular and other diseases. To study MetS, its mechanisms and means to alleviate complications associated with it, there is a demand for suitable animal models and their strains.
Jan Soukop   +9 more
wiley   +1 more source

Antibiotic‐Induced Dysbiosis of the Gut Microbiota Shifts Host Tryptophan Metabolism and Increases the Susceptibility of Mice to Pulmonary Infection With Pseudomonas aeruginosa

open access: yesImmunology, Volume 175, Issue 4, Page 453-466, August 2025.
Antibiotic‐induced dysbiosis of the gut microbiota shifts host tryptophan metabolism and impairs the innate immune response during Pseudomonas aeruginosa pulmonary infection. (A) Eubiosis: During eubiosis, the intestinal microbiota metabolises tryptophan into indole metabolites, which keeps tryptophan levels within normal serum concentrations. However,
Camila Bernardo de Brito   +19 more
wiley   +1 more source

Understanding Drug and Alcohol Staff Perspectives on the Barriers and Facilitators to Drug Checking: A Qualitative Study

open access: yesDrug and Alcohol Review, Volume 44, Issue 5, Page 1330-1338, July 2025.
ABSTRACT Introduction Drug checking (i.e., whereby members of the public submit a drug sample for pharmacological analysis of the drug content) is an evidence‐based harm reduction tool. Despite this, the uptake of drug checking services by people who use drugs (PWUD) is often limited across different jurisdictions and types of services, highlighting ...
Nina Pocuca   +6 more
wiley   +1 more source

THERMODYNAMIC ASPECTS OF SOLVATION AND DILUTION FOR ACETANILIDE AND PHENACETIN IN SOME AQUEOUS AND ORGANIC SOLVENTS MUTUALLY SATURATED ASPECTOS TERMODINÁMICOS DE LA SOLVATACIÓN Y LA DILUCIÓN DE ACETANILIDA Y FENACETINA EN ALGUNOS SOLVENTES ORGÁNICOS Y ACUOSOS MUTUAMENTE SATURADOS

open access: yesVitae, 2008
Acetanilide (ACN) and phenacetin (PNC) are compounds structurally related with acetaminophen widely used as model drugs in pharmaceutical chemistry. Based on published thermodynamic quantities for dissolution, partitioning and sublimation of ACN and PNC,
Yolima BAENA A   +2 more
doaj  

Advances in Metal‐Free Transamidation: A Sustainable Approach to Amide Bond Formation

open access: yesChemistry – An Asian Journal, Volume 20, Issue 12, June 16, 2025.
This review highlights the recent developments of transamidation reactions under metal‐free reaction conditions. Various amines including weak nucleophilic amines such as aromatic amines have been used to achieve the transamidation reactions under mild and relatively green reaction conditions. Abstract The amide functionalities are a crucial functional
Niharan Sivaraj   +2 more
wiley   +1 more source

Autoimmune Complications of Lymphoproliferative Diseases

open access: yesHematological Oncology, Volume 43, Issue S2, June 2025.
ABSTRACT Peripheral autoimmune cytopenias may complicate a fraction of lymphoproliferative disorders (LPD), particularly chronic lymphocytic leukemia, non‐Hodgkin B‐cell lymphomas, angioimmunoblastic T‐cell lymphoma and large granular lymphocytic leukemia.
Wilma Barcellini, Bruno Fattizzo
wiley   +1 more source

Paracetamol and analgesic nephropathy: Are you kidneying me?

open access: yesInternational Medical Case Reports Journal, 2014
Freya Waddington, Mark Naunton, Jackson Thomas Faculty of Health, University of Canberra, Canberra, ACT, Australia Introduction: Analgesic nephropathy is a disease resulting from the frequent use of combinations of analgesic medications over many years,
Waddington F, Naunton M, Thomas J
doaj  

Effect of Honokiol on Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes

open access: yesMolecules, 2013
Honokiol is a bioactive component isolated from the medicinal herbs Magnolia officinalis and Magnolia grandiflora that has antioxidative, anti-inflammatory, antithrombotic, and antitumor activities.
Yong Yeon Cho   +8 more
doaj   +1 more source

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