Results 31 to 40 of about 30,643 (283)
From "Special K" to "Special M" : The Evolution of the Recreational use of Ketamine and Methoxetamine [PDF]
, 2013 Objective: To review the recreational use of ketamine (‘Special K’; KET) and explore the recent diffusion of its new derivative methoxetamine (‘Special M’; MXE).
Assi, Sulaf +2 more
core +1 more source
Profiles of VGF Peptides in the Rat Brain and Their Modulations after Phencyclidine Treatment
Frontiers in Cellular Neuroscience, 2017 From the VGF precursor protein originate several low molecular weight peptides, whose distribution in the brain and blood circulation is not entirely known.
Barbara Noli +10 more
doaj +1 more source
Effects of subchronic phencyclidine on behaviour of female rats on the elevated plus maze and open field [PDF]
, 2009 YesFemale hooded-Lister rats received either sub-chronic phencyclidine (PCP) (2 mg/kg, n=20) or vehicle (1 ml/kg, n=20) i.p. twice daily for seven days, followed by a seven-day washout period. Rats were challenged with acute PCP or vehicle and tested for
Abekawa, T. +3 more
core +1 more source
Trauma Case Reports, 2020 The rapid delivery of care for penetrating traumatic injury, such as gunshot wounds, is essential to minimizing the morbidity and mortality rate. It is highly unusual for a patient who has sustained a firearm injury to present over 24 h after the event ...
Rebecca Siegel +2 more
doaj +1 more source
Analytical evaluation of a rapid on-site oral fluid drug test [PDF]
, 2010 There is a need for a reliable rapid on-site oral fluid test that can be used in police controls to detect impaired drivers. We evaluated the Varian OralabA (R) 6 and collected two oral fluid samples from 250 subjects, one with the Varian OralabA (R) 6 ...
Goessaert, An-Sofie +3 more
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Journal of Pharmacological Sciences, 2008 Drug abuse involving dextromethorphan, an antitussive, has been a social problem in various geographic locations since the 1960s. Ironically, high doses of the drug confer neuroprotective activity with central nervous system and behavioral effects ...
Eun-Joo Shin +4 more
doaj +1 more source
Interaction of the phencyclidine model of schizophrenia and nicotine on total and categorized ultrasonic vocalizations in rats [PDF]
, 2017 Patients with schizophrenia smoke cigarettes at a higher rate than the general population. We hypothesized that a factor in this comorbidity is sensitivity to the reinforcing and reinforcement- enhancement effects of nicotine.
Li, Ming +3 more
core +1 more source
Clozapine and haloperidol differently suppress the MK-801-increased glutamatergic and serotonergic transmission in the medial prefrontal cortex of the rat [PDF]
, 2007 The administration of noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonists such as phencyclidine and ketamine has been shown to increase the extracellular concentration of glutamate and serotonin (5-HT) in the medial prefrontal cortex (mPFC ...
López-Gil, Xavier +5 more
core +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source