Results 71 to 80 of about 3,715 (186)

Novel nut and bolt task quantifies motor deficits in premanifest and manifest Huntington's Disease [PDF]

, 2015
BACKGROUND: We investigated the use of a simple novel nut and bolt task in premanifest and manifest Huntington's disease (HD) patients to detect and quantify motor impairments at all stages of the disease.
Barker, Roger A,, Begeti, Faye, Collins, Lucy M, Cruickshank, Travis, Lazar, Alpar S, Lund University., Mason, Sarah L, Panin, Francesca, Ziman, Mel   +8 more
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Longitudinal changes in qualitative aspects of semantic fluency in presymptomatic and prodromal genetic frontotemporal dementia [PDF]

, 2023
Background: The semantic fluency test is one of the most widely used neuropsychological tests in dementia diagnosis. Research utilizing the qualitative, psycholinguistic information embedded in its output is currently underexplored in presymptomatic and ...
Giannini, Lucia A.A., Jiskoot, Lize C., Laenen, Sascha A.A.M., Pijnenburg, Yolande A.L., Poos, Jackie M., Satoer, Djaina D., Seelaar, Harro, van den Berg, Esther, van Hemmen, Judy, Vonk, Jet M.J.   +9 more
core   +1 more source

Cognitive profile in idiopathic autonomic failure: relation with white matter hyperintensities and neurofilament levels

Annals of Clinical and Translational Neurology, 2022
Objective To disclose the nature of cognitive deficits in a cohort of patients with idiopathic autonomic failure (IAF) by exploring the relation among cognitive functions, cardiovascular autonomic failure (AF) and clinical progression to another α ...
Ilaria Cani, Luisa Sambati, Fiorina Bartiromo, Gian Maria Asioli, Simone Baiardi, Laura M. B. Belotti, Giulia Giannini, Pietro Guaraldi, Corinne Quadalti, Luciano Romano, Raffaele Lodi, Piero Parchi, Pietro Cortelli, Caterina Tonon, Giovanna Calandra‐Buonaura   +14 more
doaj   +1 more source

Precision medication: An illustrative case series guiding the clinical application of multi‐drug interactions and pharmacogenomics

Clinical Case Reports, 2020
Precision medication entails selecting the precise medication, dose, and timing of administration. Multi‐drug interactions and genetics significantly affect precision medication. In this article, we present two simulated cases for real‐world applications
Kevin T. Bain, David McGain, Emily J. Cicali, Calvin H. Knowlton, Veronique Michaud, Jacques Turgeon   +5 more
doaj   +1 more source

NMR-based pharmacometabonomics: A new paradigm for personalised or precision medicine [PDF]

, 2017
Metabolic profiling by NMR spectroscopy or hyphenated mass spectrometry, known as metabonomics or metabolomics, is an important tool for systems-based approaches in biology and medicine.
Abo, Allalou, Anderssen, Andersson, Ashline, Backshall, Baker, Beckett, Beckonert, Bharti, Bingol, Bingol, Bouatra, Bylesjo, Chen, Clayton, Clayton, Coen, Condray, Craig, Creek, Cunningham, Dai, Daly, Ellero-Simatos, Emwas, Everett, Everett, Everett, Everett, Everett, Fennema, Fiehn, Fiehn, Gamage, Golland, Gupta, Halket, Hao, Huang, Jain, Jeremy R. Everett, Ji, Joseph, Kaddurah-Daouk, Kaddurah-Daouk, Kaddurah-Daouk, Kapoor, Karas-Kuzelicki, Keun, Kim, Kwon, Larive, Lazarou, Lewis, Lewis, Li, Lindon, Lindon, Lindon, Lindon, Liu, Marshall, Maruthur, Miolo, Muhrez, Nam, Navarro, Nicholson, Nicholson, Oliver, Perlis, Phapale, Pirmohamed, Puskarich, Rahmioglu, Robinette, Rotroff, Rubingh, Salari, Sanchon-Lopez, Schymanski, Shah, Shin, Shin, Sumner, Szymanska, Trupp, Trygg, Ulrich, Varshavi, Veselkov, Wang, Wang-Sattler, Want, Weng, Winnike, Wishart, Yerges-Armstrong, Zhang, Zhu   +100 more
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Progress on biomarkers of idiopathic rapid eye movement sleep behavior disorder conversion to neurodegenerative diseases

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
Idiopathic rapid eye movement sleep behavior disorde (iRBD) is a precursor symptom of neurodegenerative diseases, and most patients will convert to neurodegenerative diseases later in the disease. Reliable biological markers are of great significance for
ZHANG Xuan, XUE Rong
doaj   +1 more source

Generalized EEG Slowing Across Phasic REM Sleep, Not Subjective RBD Severity, Predicts Neurodegeneration in Idiopathic RBD

Nature and Science of Sleep, 2022
Si-Yi Gong,1,* Yun Shen,1,* Han-Ying Gu,1 Sheng Zhuang,1 Xiang Fu,1,2 Qiao-Jun Wang,1 Cheng-Jie Mao,1 Hua Hu,1 Yong-Ping Dai,1 Chun-Feng Liu1– 3 1Department of Neurology and Clinical Research Center of Neurological Disease, The Second Affiliated ...
Gong SY, Shen Y, Gu HY, Zhuang S, Fu X, Wang QJ, Mao CJ, Hu H, Dai YP, Liu CF   +9 more
doaj  

Equine epidermis : a source of epithelial-like stem/progenitor cells with in vitro and in vivo regenerative capacities [PDF]

, 2014
Besides the presence of somatic stem cells in hair follicles and dermis, the epidermis also contains a subpopulation of stem cells, reflecting its high regenerative capacity.
Aerts, Désirée, Broeckx, Sarah, Chiers, Koen, Franco-Obregón, Alfredo, Maes, Sofie, Mariën, Tom, Martinello, Tiziana, Patruno, Marco, Spaas, Jan   +8 more
core   +2 more sources

Validation of the REM behaviour disorder phenoconversion-related pattern in an independent cohort [PDF]

, 2023
Background: A brain glucose metabolism pattern related to phenoconversion in patients with idiopathic/isolated REM sleep behaviour disorder (iRBDconvRP) was recently identified.
Arnaldi, Dario, Bauckneht, Matteo, Chiaravalloti, Agostino, Donniaquio, Andrea, Famà, Francesco, García, David Vállez, Kim, Heejung, Kim, Ryul, Kim, Yu Kyeong, Lee, Jee Young, Leenders, Klaus L., Liguori, Claudio, Massa, Federico, Mattioli, Pietro, Meles, Sanne K., Morbelli, Silvia, Nobili, Flavio, Orso, Beatrice, Pardini, Matteo, Shin, Jung Hwan, Yoon, Eun Jin   +20 more
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Mild behavioral impairment linked to phenoconversion to Alzheimer’s disease and cortical thinning in mild cognitive impairment [PDF]

, 2023
Eun Jin Yoon, Jun‐Young Lee, Seyul Kwak, Heejung Kim, Yu Kyeong Kim   +4 more
openalex   +1 more source