Results 231 to 240 of about 161,426 (311)

In vitro adventitious root culture of Withania somnifera L.: a strategy for enhanced secondary metabolite production with therapeutic antioxidant and anti-inflammatory potential. [PDF]

Sci Rep
Mohammed DM, Abdelazeez WMA, Suliman AA, Sallam ARM, Sief-Eldein AGM, Aboueldis GR.   +5 more
europepmc   +1 more source

Electrical Stimulation Directs Formation of Perfused Vasculature in Engineered Tissues

Advanced Science, EarlyView.
Electrical stimulation (ESTIM) enhances vasculature formation in engineered human tissues. In 3D endothelial‐fibroblast constructs, conditioning with ESTIM promotes the formation of dense and highly branched networks that rapidly anastomose with mouse vasculature when implanted in vivo. Vessels formed under ESTIM are importantly functionally perfusable.
Katarzyna A. Grzelak, Ashley D. Westerfield, Vardhman Kumar, Kasturi Chakraborty, Navaneeth Krishna Rajeeva Pandian, Christopher S. Chen, Sangeeta N. Bhatia   +6 more
wiley   +1 more source

Terrestrial Plant- and Algal-Derived Biostimulants as Modulators of ROS and Hormone Networks in Crop Abiotic Stress Resilience. [PDF]

Plants (Basel)
Minkov P, Gechev TS, Kanojia A.
europepmc   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

Integrated metabolomic, network pharmacological, and molecular docking analyses comparing the therapeutic effects of Strobilanthes sarcorrhiza from different origins. [PDF]

Sci Rep
Xie W, Gao H, Zhu Z, Xu X, Ying Y, Yan Y, Ding L, Wu G.   +7 more
europepmc   +1 more source

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

Advanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen, Xinkai Pu, Ruiyang Li, Yuezhou Wu, Qirong Zhou, Jian Wang, Yuxuan Qian, Fengjie Lu, Jian‐Yuan Zhao, Zhida Su, Jiacan Su, Xiaofeng Lian   +11 more
wiley   +1 more source

In vitro digestion of custard apple pulp: bioaccessibility of phenolic compounds, bioactive amines, and effect on antioxidant potential. [PDF]

Eur J Nutr
Todescato AP, de Oliveira PF, Ávila PF, do Vale-Oliveira M, Custódio FB, Gloria MBA, Dala-Paula BM.   +6 more
europepmc   +1 more source

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

Evaluation of <i>Ulva lactuca</i> hydrolysates as a feedstock for clostridial fermentations to produce 1,2-propanediol. [PDF]

Front Microbiol
Ingvadottir EM, Scully SM, Orlygsson J.
europepmc   +1 more source

Phenolic Antioxidants in the Adriatic Halophyte <i>Limbarda crithmoides</i>: Variation Across Phenological Stages. [PDF]

Foods
Brzović P, Radman S, Mekinić IG.
europepmc   +1 more source