A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Photochemical UV/TiO2 treatment of olive mill wastewater (OMW) [PDF]
, 2008 Olive mill wastewater (OMW) was treated by photocatalysis using TiO2 under UV irradiation on the laboratory scale. The chemical oxygen demand, the coloration at 330 nm, and the level of phenols all showed decreases which, after a 24-h treatment, reached ...
Bailly, Jean-René +7 more
core +3 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Hypoglicemic and Hypolipedimic Effects of Ganoderma lucidum in Streptozotocin-Induced Diabetic Rats
Medicines, 2018 Background:Ganoderma lucidum (Leyss. Ex. Fr) Karst is a basidiomycete mushroom that has been used for many years as a food supplement and medicine. In Brazil, National Health Surveillance Agency (ANVISA) classified Ganoderma lucidum as a nutraceutical ...
Erna Elisabeth Bach +4 more
doaj +1 more source
THE INFLUENCE OF CERIUM DIOXIDE NANOPARTICLES ON GERMINATION OF SEEDS AND PLASTIC EXCHANGE OF PINE SEEDLINGS (Pinus sylvestris L.) [PDF]
Biotechnologia Acta, 2017 The aim of this work was to study the effect of cerium dioxide nanoparticles on the germination of Scots pine (Pinus sylvestris) seeds and the subsequent physiological changes in plastid pigments and phenolic compounds accumulation in the seedlings ...
A. P. Pinchuk +7 more
doaj +1 more source
American Journal of Public Health, 1921 The author states that a phenol coefficient indicates relative germicidal efficiency under laboratory conditions only, and has no practical value. Users of disinfectants ordinarily “follow directions,” and employ the dilutions recommended by the manufacturers.
openaire +3 more sources
Competitive adsorption of p-hydroxybenzoic acid and phenol on activated carbon : experimental study and modelling. [PDF]
, 2013 The competitive adsorption of phenol and p-hydroxybenzoic acid (4HBA) has been investigated on activated carbon (AC) for a wide range of concentrations under unbuffered conditions. The results show a preferential adsorption of 4HBA which can be explained
Andriantsiferana, Caroline +4 more
core +2 more sources
In-vitro antioxidant and anti-inflamatory activities of Pituranthos chloranthus and Artemisia vulgaris from Tunisia [PDF]
, 2020 Pituranthos chloranthus and Artemisia vulgaris L. are two of the most important aromatic and medicinal species from the Apiaceae and Asteraceae families, respectively. They are traditionally used in certain pathologies in which inflammatory processes are
AAZZA, Smail +3 more
core +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Agriculture, 2023 Drought stress is a significant environmental variable affecting wheat growth and development. Plant stress tolerance is intimately related to growth regulators of plants as polyamines.
Hebat-Allah A. Hussein +4 more
doaj +1 more source