Results 171 to 180 of about 197,703 (204)

Polygenic risk score and phenome-wide association study of the Epstein-Barr virus antibody response. [PDF]

Front Genet
Namjou B, Lape M, Weirauch MT, Kaufman KM, Kottyan LC.   +4 more
europepmc   +1 more source

P710: Phenome-wide association study (PheWAS) for the Canadian HostSeq Biobank

Genetics in Medicine Open
Erika Frangione, Xu Xinyi, Vincent Chapdelaine, Selina Casalino, Navneet Aujla, Radhika Mahajan, Lochana Jayachandran, Gregory Morgan, Mackenzie Scott, Juliet Young, Brendan Dickson, Saranya Arnoldo, Erin Bearss, Alexandra Binnie, Bjug Borgundvaag, Howard Chertkow, Marc Clausen, Marc Dagher, Luke Devine, Steven Friedman, Anne-Claude Gingras, Lee Goneau, Deepanjali Kaushik, Zeeshan Khan, Elisa Lapadula, Georgia MacDonald, Tony Mazzulli, Allison McGeer, Shelley McLeod, Chloe Mighton, Trevor Pugh, David Richardson, Jared Simpson, Seth Stern, Lisa Strug, Ahmed Taher, Iris Wong, Natasha Zarei, Elena Greenfeld, Yvonne Bombard, Abdul Noor, Hanna Faghfoury, Jennifer Taher, Daniel Taliun, Jordan Lerner-Ellis   +44 more
openaire   +2 more sources

Causal cross-trait mapping at single-cell resolution identifies shared immunogenetic drivers of migraine and Meniere's disease. [PDF]

J Headache Pain
Hu X, Wang Y, Yu SJ, Pan CY, Liang BY, Jiang SS, Chen SW, Han YX.   +7 more
europepmc   +1 more source

Heart rate phase is an indicator of chronotype-relevant circadian shifts associated with human disease: an All of Us Research Program analysis. [PDF]

J Physiol
Chan ZM, Patel PP, Levitsky GM, McClung CA, Nouraie SM, Kelly NJ.   +5 more
europepmc   +1 more source

Genetic evidence supporting obesity as a risk factor for lung squamous cell carcinoma and the identification of MFAP1 as a shared genetic target. [PDF]

Discov Oncol
Xu K, Liu T, Li Z, Wang M, Yang Z, Chen X, Wang Y, Chen Y, Lin Y, Wang Y, Zhong G, Zhai X.   +11 more
europepmc   +1 more source

Inclusion bias affects common variant discovery and replication in a health-system linked biobank. [PDF]

Am J Hum Genet
Pimplaskar A, Qiu J, Lapinska S, Tozzo V, Chiang JN, Pasaniuc B, Olde Loohuis LM.   +6 more
europepmc   +1 more source

A Phenome-Wide Association and Mendelian Randomization Study of Genetically Predicted Membranous Nephropathy with Multiple Diseases.

Kidney Blood Press Res
Wenghaerbai A, Alemasi A, Gu L, Deng J, Zhou Y.   +4 more
europepmc   +1 more source

Circulating Plasma Proteins Influence the Risk of Aortic Dissection via Blood Pressure: A Network Mendelian Randomization and Multi-Omics Study. [PDF]

J Inflamm Res
Li Z, Liu J, Fan X, Shi L, Shi H, Li C, Duan C, Zhang C, Wu Q, Shao Y.   +9 more
europepmc   +1 more source

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Are phenome-wide association studies feasible in a developing country?

Trends in Genetics, 2022
Phenome-wide association studies (PheWASs), a powerful approach that examines phenotypes associated with a genetic marker, have been used extensively in highly developed countries.
G. Dumancas, Destiny Harrison, Jonathan Adam A. Rico, P. R. F. Zamora, Aretha G. Liwag, Joselito F. Villaruz, M. Guanzon, H. F. D. Ferraris, Patrick Joseph B. Jalandoni, Webster F. Padernal, B. N. L. Villareal, Ria A. Maculada, R. Fernández, Felix Ray P. Villa, R. de Castro   +14 more
semanticscholar   +5 more sources

Unravelling the human genome–phenome relationship using phenome-wide association studies

Nature Reviews Genetics, 2016
Advances in genotyping technology have, over the past decade, enabled the focused search for common genetic variation associated with human diseases and traits. With the recently increased availability of detailed phenotypic data from electronic health records and epidemiological studies, the impact of one or more genetic variants on the phenome is ...
W. Bush, Matthew Oetjens, D. Crawford
semanticscholar   +5 more sources