Results 151 to 160 of about 22,489,720 (176)

Phenome-wide association studies on a quantitative trait: application to TPMT enzyme activity and thiopurine therapy in pharmacogenomics. [PDF]

PLoS Comput Biol, 2013
Neuraz A, Chouchana L, Malamut G, Le Beller C, Roche D, Beaune P, Degoulet P, Burgun A, Loriot MA, Avillach P.   +9 more
europepmc   +1 more source

Accelerometer-derived real-world sleep stages and risk of incident diseases: A UK Biobank cohort study and phenome-wide association analysis. [PDF]

PLoS Med
Luo J, Liu R, Yin J, Cao W, Sun S, Chen R.   +5 more
europepmc   +1 more source

Systematic comparison of phenome-wide admixture mapping and genome-wide association at biobank-scale. [PDF]

Nat Commun
Cullina S, Shemirani R, Shi Z, Mandla R, Pasaniuc B, Asgari S, Kenny EE.   +6 more
europepmc   +1 more source

The Omnicausal Model Reveals the Highly Polyfactorial Nature of Complex Diseases. [PDF]

Genet Epidemiol
Márquez-Luna C, Tournaire M, Rocheleau G, Do R, Verbanck M.   +4 more
europepmc   +1 more source

Plasma Proteome-Wide Mendelian Randomization with Multi-Layer Triangulation Identifies Druggable Targets for Uterine Leiomyoma. [PDF]

Int J Womens Health
Wang X, Yao G, Ding W.
europepmc   +1 more source

Robust replication of associations across patient-mediated and provider-sourced EHR data in the <i>All of Us</i> research program. [PDF]

NPJ Digit Public Health
Zeng C, Waxse BJ, Denny JC.
europepmc   +1 more source

Integrative statistical genetics prioritizes candidate ASCVD susceptibility genes across tissues. [PDF]

Mol Med
Liu Q, Han X, Hu YQ, Fu L.
europepmc   +1 more source

A multi-ancestry genome-wide association study of dry eye disease and systemic comorbidities. [PDF]

EBioMedicine
Gorman BR, Huang JJ, Barr PB, Halladay CW, Nealon CL, Chatzinakos C, Francis M, Jiang C, Greenberg PB, Wu WC, Pyarajan S, Choquet H, Bigdeli TB, Iyengar SK, Peachey NS, Galor A, VA Million Veteran Program.   +16 more
europepmc   +1 more source

Integrative proteogenomic analyses identify plasma proteins that impact the risk of ischemic stroke. [PDF]

Commun Med (Lond)
Belbasis L, von Ende A, Gajendragadkar P, Valdes-Marquez E, Murgia F, van Duijn C, Hopewell JC.   +6 more
europepmc   +1 more source

Genetic regulation of cell type-specific chromatin accessibility contributes to migraine etiology. [PDF]

J Headache Pain
Xu Q, Chai Z, Zhang Y, Shen J.
europepmc   +1 more source