Results 131 to 140 of about 10,755 (158)

Are phenome-wide association studies feasible in a developing country?

Trends in Genetics, 2022
Phenome-wide association studies (PheWASs), a powerful approach that examines phenotypes associated with a genetic marker, have been used extensively in highly developed countries. Although there may be a clear need for PheWAS in a developing country such as the Philippines, limitations related to resources and practicality would make conducting them a
Romulo De Castro
exaly   +3 more sources

Genome–phenome wide association study of broadly defined headache

open access: yesBrain Communications, 2023
Abstract Until recently, most genetic studies of headache have been conducted on participants with European ancestry. We therefore conducted a large-scale genome-wide association study of self-reported headache in individuals of East Asian ancestry (specifically those who were identified as Han Chinese).
Xia Jiang, Frank Qian, Sung-Chun Tang
exaly   +3 more sources

Genome-Wide Association Study of Intracranial Artery Stenosis Followed by Phenome-Wide Association Study

Translational Stroke Research, 2022
The genetic background of intracranial artery stenosis (ICAS), a major cause of ischemic stroke, remains elusive. We performed the world's first genome-wide association study (GWAS) of ICAS using DNA samples from Japanese subjects, to identify the genetic factors associated with ICAS and their correlation with clinical features.
Shogo Dofuku   +25 more
openaire   +2 more sources

THE TREND TOWARDS PHENOME-WIDE ASSOCIATION STUDIES (PheWASs) IN COVID-19 RESEARCH [PDF]

open access: possibleSOUTHERN JOURNAL OF SCIENCES, 2022
Background: Coronavirus Disease-2019 (COVID-19) appears in individuals asymptomatically and in various symptomatic forms. Symptomatic diversity can result in diagnosis failures, hospitalization, admission to intensive care, multi-organ failure, and death. The causes and risk factors of the severity of disease symptoms are uncertain.
Atçeken, Nazente   +3 more
openaire   +1 more source

Phenome-Wide Association Study

2016
J.L. Warner, J.C. Denny
exaly   +2 more sources

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