Results 71 to 80 of about 21,579,379 (182)
Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes [PDF]
, 2014 Type 2 diabetes (T2D) is more prevalent in African Americans than in Europeans. However, little is known about the genetic risk in African Americans despite the recent identification of more than 70 T2D loci primarily by genome-wide association studies ...Rasmussen-Torvik, Laura J., Ayo Doumatey, Jennifer A. Pacheco (496628), MEDIA Consortium (), Daniel S. Evans (230365), Dhananjay Vaidya, Liu, YM, Loren L Armstrong, McKnight, Barbara, Lynne Wagenknecht (610797), Boerwinkle, E., Zhao, W, Fornage, Myriam, M Geoffrey Hayes, Beverly M. Snively (156128), Palmer, N.D., Becker, Diane M, Langefeld, Carl D, Goodarzi, Mark O., Sudha K. Iyengar (129292), James G. Wilson (113688), Mathias, Rasika A, Peyser, Patricia A., Chen, B.H., Myriam Fornage (45591), Kao, W.H.L., Jensen Richard A., Rice Kenneth, Liu Simin, Borecki, IB, Kraja, A, Borecki, Ingrid B., Yanek, LR, Yang Lingyao, Palmer Nicholette D., Rasmussen-Torvik, Laura J, Kabagambe, E.K., Lowe, W.L., Adeyemo Adebowale, Leslie J Raffel, Laura J. Rasmussen-Torvik (174672), Iyengar, S.K., Palmer, Nicholette D, Doumatey, A, Boerwinkle, Eric, Bowden, Donald W, Nalls, Michael A., Doumatey, Ayo, Xiuqing Guo (73591), Armstrong, Loren L., Zhao, Wei, Evans, Michele K., Chen, Y.-D. Ida, Boerwinkle, E, Bowden, D.W., Y-D Ida Chen (610799), Dana C. Crawford (102216), Pacheco, J.A., Taylor, HA, Chen, Brian H, Guanjie Chen, Evans, DS, Raffel, LJ, William L Lowe, Rich, Stephen S., Alan B. Zonderman (178692), Sedor, J.R., Hsueh, Wen-Chi, Chen, Guanjie, Jensen, Richard A., Wen-Chi Hsueh, Ping An (24129), Couper, David J., Michael A Province, Mudgal, P., Becker, D.M., Dana C Crawford, Andrew B. Singleton (178128), Guo Xiuqing, Crawford, DC, Barry I. Freedman (120811), Lu, YC, Langefeld, CD, Vaidya, Dhananjay, Cummings, Steven R, Taylor, H.A.J., Goodarzi Mark O., Rasmussen-Torvik, LJ, Bielak Lawrence F., Lu, Y., Jirong Long, Simin Liu, Erwin P. Bottinger (3212694), Zonderman Alan B., ?, ?, Sale Michèle M., Wei Zhao, Freedman, BI, Blot, William J., Steven R Cummings, Aldi Kraja, McKnight, B., Pankow James S., Cummings, Steven R., Lu, Yingchang, Province, MA, Peyser, PA, Borecki, Ingrid B, Ping An, Kao, WH Linda, Raffel Leslie J., Rotimi, Charles N, Nalls, M.A., Nicholette D. Palmer (190239), Shu, X.O., Jennifer A Pacheco, McKnight Barbara, Robert P. Igo Jr. (5660086), Aldi Kraja (73605), Vaidya, D, James S Pankow, Chen, Y-D Ida, Sedor, John R., Sedor, John R, Guo, Xiuqing, MuTHER Consortium (), Leslie J. Raffel (610798), Rice, Kenneth, Sun, Y.V., Keene Keith L., Wei Zheng, Lawrence F Bielak, Mark O. Goodarzi (123440), Wagenknecht Lynne, Crawford, D.C., FIND Consortium (), Li, Jiang, Herman A. Taylor Jr. (5660083), Adebowale Adeyemo, Xiao-Ou Shu, Bielinski, S.J., Mathias, Rasika A., Armstrong, LL, Rotimi, CN, Hayes, M Geoffrey, David S. Siscovick (174822), Chen Wei-Min, Sale, Michèle M., Rotter, Jerome I, Maggie C. Y. Ng (190281), An, P., Rice, K., Mudgal Poorva, Bowden, Donald W., Long, Jirong, Hayes, MG, David S Siscovick, Lowe, WL, Singleton, Andrew B., Adolfo Correa, Igo Robert P., Yanek Lisa R., Loos, Ruth J. F., Yanek, Lisa R, DIAGRAM Consortium, Barbara McKnight, Ng, MCY, Loos, RJF, Bowden Donald W., Raffel, L.J., Yingchang Lu, Nicholette D Palmer, Diane M Becker, Sims, M, Armstrong, L.L., Evans, M.K., Wilson, James G, Adeyemo, Adebowale, Omri Gottesman, Palmer, Nicholette D., Sun, Yan V, Jensen, R.A., Chen Brian H., Couper David, Langefeld Carl D., Shu, X., Lawrence F. Bielak (446522), Josyf C. Mychaleckyj (171602), Nayak Uma, Sun, Yan V., Long Jirong, Sims Mario, Kraja Aldi, Ng Maggie C. Y., Laura J Rasmussen-Torvik, Chen, Y.I., Goodarzi, Mark O, Chen, Brian H., Province Michael A., Rasika A Mathias, Grundberg, E, Comeau, Mary E, Mychaleckyj, JC, Keene, K.L., James S. Pankow (174656), Igo, R.P., Wagenknecht, Lynne, Rich Stephen S., Mychaleckyj, Josyf C., Bruce M Psaty, Snively Beverly M., Hayes M. Geoffrey, Freedman, B.I., Ruth J F Loos, Armstrong Loren L., Vaidya Dhananjay, Shriner, D, Yingchang Lu (149264), DIAGRAM Consortium (Gieger, C. ; Grallert, H. ; Illig, T. ; Klopp, N. ; Müller-Nurasyid, M. ; Peters, A.), Gottesman, O., Rotter Jerome I., Lingyao Yang (215359), M. Geoffrey Hayes (327753), Kao, WHL, Rotter, J.I., An Ping, William J. Blot (191278), Yang, LY, Nalls, Michael A, Couper, David, Bottinger, Erwin P, Loren L. Armstrong (529937), Crawford, Dana C, Grundberg Elin, Carl D. Langefeld (120828), Kraja, A., Pacheco, Jennifer A., John R. Sedor (306528), Patel, S.R., Michèle M Sale, Correa, A, Chen, GJ, Bottinger, Erwin P., Guo, XQ, Wilson, James G., Pankow, James S., Suzette J Bielinski, W H Linda Kao, Jerome I. Rotter (103729), Singleton, A.B., Yongmei Liu, Myriam Fornage, Bottinger Erwin P., Eric Boerwinkle, Becker, Diane M., Patel, Sanjay R., Yang, L., Evans Daniel S., Rotimi, Charles N., Langefeld, Carl D., Sale, M.M., Keith L Keene, Sale, MM, Peyser Patricia A., Chen, G., Zheng, W, Blot, W.J., Patel, Sanjay R, Diane M. Becker (113669), Sudha K Iyengar, Doumatey Ayo, Keene, KL, Iyengar Sudha K., Lynne Wagenknecht, Ayo Doumatey (255558), W. H. Linda Kao (160779), Chen, Y.-D.I., Hsueh Wen-Chi, Armstrong, Loren L, Pacheco Jennifer A., Gottesman, O, Sims, Mario, Brian H. Chen (610796), Daniel S Evans, Gottesman, Omri, Goodarzi, MO, Michael A. Province (53600), Elin Grundberg, Mychaleckyj, Josyf C, Robert P Igo, Rotter, JI, David Couper (215307), Zonderman, Alan B., Becker, DM, Psaty, Bruce M., Daniel Shriner, Y-D Ida Chen, Charles N. Rotimi (137216), Bielak, L.F., Lowe, William L., Long, J., Bielak, Lawrence F, Liu, J., Taylor, Herman A, Kenneth Rice, Jiankang Liu, Evans, Daniel S, Zonderman, Alan B, Mathias, RA, Raffel, Leslie J., Beverly M Snively, Zheng Wei, Kraja, Aldi, Liu, JK, Michele K Evans, Zheng, W., An, P, Wei Zhao (14321), Jirong Long (181371), Kao W. H. Linda, Borecki Ingrid B., Wilson James G., Cummings, S.R., Patricia A Peyser, Guanjie Chen (28943), Zonderman, AB, Cummings, SR, Richard A. Jensen (103656), Jiankang Liu (48049), Taylor, H.A., Fornage Myriam, Uma Nayak (446511), Ruth J. F. Loos (110224), Sims, M., Bielinski Suzette J., Poorva Mudgal (522965), Mario Sims, Kabagambe, Edmond K., Guo, X., Chen, BH, Patel, SR, Josyf C Mychaleckyj, Rasika A. Mathias (134405), Ng, Maggie CY, Donald W Bowden, Mudgal, P, Psaty, Bruce M, Doumatey, A., William L. Lowe (610802), Mathias Rasika A., Igo, Robert P., Shriner Daniel, Nayak, U, Simin Liu (11987), Charles N Rotimi, Grundberg, Elin, Michael A. Nalls (113680), Correa Adolfo, Long, JR, Bottinger, EP, Qiuyin Cai (25449), Bielinski, SJ, Liu, Jiankang, Mary E. Comeau (192855), Igo, R.P.J., Wilson, J.G., Edmond K Kabagambe, Jiang Li, Adeyemo, A, Mark O Goodarzi, Mario Sims (412259), Siscovick, DS, Uma Nayak, Bielak, LF, Evans, MK, Elin Grundberg (116416), Mudgal, Poorva, McKnight, B, Freedman Barry I., Cai Qiuyin, Province, M.A., Hayes, M.G., Blot, WJ, Correa, A., Rich, SS, Lisa R Yanek, MEta-analysis of type 2 DIabetes in African Americans Consortium, Singleton Andrew B., Langefeld, C.D., Mychaleckyj, J.C., Shu, XO, Freedman, Barry I, Sanjay R. Patel (120915), Becker Diane M., Lingyao Yang, Edmond K. Kabagambe (127046), Palmer, ND, Jiang Li (272926), Siscovick David S., Igo, RP, Wen-Chi Hsueh (264276), Michèle M. Sale (113676), Chen Guanjie, Comeau, ME, Li, J, Cummings Steven R., Keene, Keith L, Iyengar, Sudha K., Xiao-Ou Shu (25450), Ingrid B. Borecki (113678), Fornage, M., Singleton, Andrew B, Zheng, Wei, Bruce M. Psaty (103721), Shriner, Daniel, Bielak, Lawrence F., Kabagambe Edmond K., Evans, Daniel S., Eric Boerwinkle (36288), Chen, Wei-Min, Rasmussen-Torvik Laura J., Wei-Min Chen (110472), Comeau, M.E., Rasmussen-Torvik, L.J., Sedor John R., Liu, SM (Simin), William J Blot, Patricia A. Peyser (446515), Wei Zheng (25452), Ng, Maggie C. Y., Pacheco, JA, Jensen, Richard A, Hayes, M. Geoffrey, Jerome I Rotter, Siscovick, David S., Kabagambe, Edmond K, Liu, Simin, Kabagambe, EK, Nayak, Uma, Michele K. Evans (27920), Maggie C Y Ng, Yanek, L.R., Rich, S.S., Gottesman Omri, Chen, YDI, Keene, Keith L., Bowden, DW, Couper, D, Mychaleckyj Josyf C., Crawford, Dana C., Raffel, Leslie J, Liu, Yongmei, Sun Yan V., Yanek, Lisa R., Grundberg, E., Liu, S., Rice, K, Ingrid B Borecki, Hsueh, W.C., Snively, Beverly M, Province, Michael A., Peyser, P.A., Crawford Dana C., Rotimi Charles N., Li, J., Comeau Mary E., Boerwinkle Eric, Cai, Q., Freedman, Barry I., Vaidya, D., Barry I Freedman, David Couper, Poorva Mudgal, Nalls, MA, Pacheco, Jennifer A, Hsueh, WC, Fornage, M, Bottinger, E.P., Zhao, W., Cai, Qiuyin, John R Sedor, Snively, B.M., Igo, Robert P, Adolfo Correa (610800), Shu Xiao-Ou, Qiuyin Cai, Siscovick, D.S., Pankow, JS, Comeau, Mary E., Siscovick, David S, FIND Consortium, Rotimi, C.N., Sale, Michèle M, Erwin P Bottinger, Iyengar, Sudha K, Cai, QY, Taylor Herman A., Taylor, Herman A., Sedor, JR, Mathias, R.A., Michael A Nalls, Zhao Wei, Loos Ruth J. F., Yan V Sun, Evans, Michele K, Liu Yongmei, Suzette J. Bielinski (262597), Omri Gottesman (133442), Nalls Michael A., Donald W. Bowden (120806), Shriner, D., Yang, Lingyao, Rich, Stephen S, An, Ping, Adeyemo, A., Blot, William J, Goodarzi, M.O., Sanjay R Patel, Alan B Zonderman, Pankow, James S, Lowe, William L, Daniel Shriner (137188), Xiuqing Guo, Bielinski, Suzette J., Wagenknecht, L, Lisa R. Yanek (113564), Chen Y-D Ida, Psaty, BM, Snively, Beverly M., Adebowale Adeyemo (28944), Wagenknecht, L., Evans Michele K., Steven R. Cummings (361400), Bielinski, Suzette J, Herman A Taylor, Andrew B Singleton, Loos, R.J.F., Psaty, B.M., MuTHER Consortium, Wilson, JG, Barbara McKnight (103714), Brian H Chen, Iyengar, SK, Stephen S. Rich (110262), Ng, M.C.Y., Hsueh, W., Lu Yingchang, Province, Michael A, Singleton, AB, Pankow, J.S., Carl D Langefeld, Zonderman, A.B., Jensen, RA, Chen, WM, Psaty Bruce M., Couper, D., Stephen S Rich, Sun, YV, Correa, Adolfo, Yan V. Sun (446508), Shu, Xiao-Ou, Blot William J., Borecki, I.B., James G Wilson, Kao, W. H. Linda, Evans, D.S., Nayak, U., Peyser, Patricia A, Snively, BM, Mary E Comeau, Liu, Y., Richard A Jensen, Chen, W., Rotter, Jerome I., Wei-Min Chen, Lowe William L., Dhananjay Vaidya (149887), eMERGE Consortium, Liu Jiankang, Kenneth Rice (211836), Yongmei Liu (104713), Patel Sanjay R., eMERGE Consortium (), Keith L. Keene (540212), Li Jiang, Loos, Ruth JF +585 morecore +2 more sourcesAn early-onset specific polygenic risk score optimizes age-based risk estimate and stratification of prostate cancer: population-based cohort study
Journal of Translational MedicineBackground Early-onset prostate cancer (EOPC, ≤ 55 years) has a unique clinical entity harboring high genetic risk, but the majority of EOPC patients still substantial opportunity to be early-detected thus suffering an unfavorable prognosis.Yifei Cheng, Lang Wu, Junyi Xin, Shuai Ben, Silu Chen, Huiqin Li, Lingyan Zhao, Meilin Wang, Gong Cheng, Mulong Du +9 moredoaj +1 more sourcePTEN homozygous deletion is a negative prognostic factor in tumor treating fields‐treated glioblastoma, IDH wildtype patients
Brain Pathology, EarlyView.In a molecularly confirmed cohort of 64 newly diagnosed, TTFields‐treated glioblastomas, IDH‐wildtype, homozygous PTEN deletion was associated with markedly shorter overall survival (368 vs. 603 days) and remained an independent adverse prognostic factor.Jakob Nückles, Claudius Jelgersma, Christin Siewert, Brendan Osberg, Simone Schmid, Arend Koch, Eilís Perez, Daniel Teichmann, Martin Misch, Anna‐Gila Karbe, Susanne Ukrow, Patrick N. Harter, Ruth M. Stassart, Peter Vajkoczy, Julia Onken, David Capper +15 morewiley +1 more sourceEvaluation of association of HNF1B variants with diverse cancers : collaborative analysis of data from 19 genome-wide association studies [PDF]
, 2010 Background
Genome-wide association studies have found type 2 diabetes-associated variants in the HNF1B gene to exhibit reciprocal associations with prostate cancer risk.Tomlinson, IP, Mann, GJ, Hwang, Shih-Jen, Hopper, John L., Hwang, SJ, Amos, CI, Barkardottir, Rosa B., McCarthy, Mark I, Carvajal-Carmona Luis, Albanes, D, Xu, J, Armstrong, Bruce K., Kenneth Muir, Stefansson Kari, Jacobs, EJ, Amos Christopher I., Zanke, B, Barkardottir, Rosa B, Jenab, M, Michaud, DS, Xu Jianfeng, Mendelsohn, JB, Muir, K, Hamdy, Freddie C., Stolzenberg-Solomon, RZ, Aitken, JF, Mathieu Lemire, Aitken, Joanne F., John P. A. Ioannidis, null null, Hunter, David, Hallmans, G, Donovan, Jenny L, Murabito Joanne M., Risch, HA, Hamdy, FC, Rafnar Thorunn, Giles, Graham G., Donovan, JL, Tomlinson, Ian P. M., Hunter David J., Margaret R Spitz, Macgregor, Stuart, Tomlinson Ian P. M., Spitz, Margaret R., Hopper, JL, David E. Neal, Duell, EJ, Stefansson, K, Simon N Stacey, Gudbjartsson, Daniel F, Julius Gudmundsson, David J Hunter, Armstrong, BK, Neal David E., Easton Douglas F., Amundadottir, L, Kari Stefansson, Stephen J Chanock, Hayward Nicholas K., Zeggini, E, Neal, David E, Isaacs, William B, Easton, DF, Chanock, Stephen J, Patel, AV, Douglas F. Easton, Brown Kevin M., Petersen, GM, Thorlacius, Steinunn, Isaacs, William B., William B Isaacs, Gallinger, S, Klein, AP, Gaborieau Valerie, Donovan, Jenny, Kraft, P, Kevin M Brown, Giovannucci, EL, Holly, EA, Lemire, Mathieu, Rosa B. Barkardottir, Sulem, P, Barkardottir, RB, Neal, David E., Zeggini, Eleftheria, Valerie Gaborieau, Chanock, Stephen J., Kevin M. Brown, Zeggini Eleftheria, Barkardottir, Rosa, HASH(0x55a67fc6f008), Riboli, E, Hayward, NK, Shu, XO, Howard, B, David E Neal, Stacey, Simon N., Gronberg, H, PanScan, C, Parikh, H, Gudmundsson Julius, Hassan, M, Ian P. M. Tomlinson, Tomlinson, IPM, Ioannidis, JPA, Gudmundsson, Julius, Carvajal-Carmona, Luis, McCarthy, MI, Kefford, Richard F., Clipp, S, McCarthy Mark I., Donovan Jenny L., Brent Zanke, Muir, Kenneth, Neal, DE, Ioannidis, John P., Li, D, Amundadottir Laufey, Canzian, F, Eeles, RA, Rodriguez, L, Gudmundsson, J, Mark I. McCarthy, Xu, Jianfeng, Elliott, Katherine S, Hutchinson, A, Krogh, V, Mann, Graham J., Thomas, G, Ioannidis, John PA, Eeles Rosalind A., Brown, Kevin M., Stacey, SN, Ioannidis, John, Kefford, RF, Sulem, Patrick, Katherine S Elliott, Gudbjartsson Daniel F., Murabito, JM, Stacey Simon N., McCarthy, Mark I., Gudbjartsson, DF, Hamdy Freddie C., Jenny L. Donovan, Eleftheria Zeggini, Hunter, David J., Luis Carvajal-Carmona, Chanock, Stephen, Hayward, Nicholas K., Michael Gaziano, J, Hunter, David J, Shih-Jen Hwang, Jianfeng Xu, The PanScan Consortium, Buring, JE, Amos, Christopher I, Henrik Grönberg, PanScan Consortium, Giles, GG, Rafnar, Thorunn, Easton, Douglas F, Nicholas K. Hayward, Brown, KM, Chanock Stephen J., Jenny L Donovan, Rosalind A Eeles, Arslan, AA, Seminara, D, Goggins, M, Stefansson, Kari, Murabito, Joanne M., Hunter, DJ, McCarthy, Mark, Tomlinson, Ian PM, Donovan, Jenny L., Rajkovic, A, Zanke Brent, Hamdy, Freddie C, Nicholas K Hayward, Thorlacius Steinunn, Hayward, Nicholas K, Joanne M. Murabito, Lynch, SM, Isaacs William B., Daniel F. Gudbjartsson, Elliott, Katherine S., Ioannidis, John P. A., Fuchs, CS, de Andrade, M, Hankinson, SE, Grönberg Henrik, Lemire Mathieu, Christopher I. Amos, Gross, M, Mandelson, MT, Spitz, Margaret R, Ioannidis, John P.A., Helzlsouer, K, Laufey Amundadottir, Bracci, PM, Tomlinson, Ian, Kooperberg, C, Kurtz, RC, Grönberg, H, John P A Ioannidis, Sulem Patrick, Eeles, Rosalind A, McWilliams, RR, Gaborieau, V, Elliott Katherine S., Ioannidis, JP, Christopher I Amos, Tjønneland, A, Stuart Macgregor, Rosalind A. Eeles, Berg, CD, Rosa B Barkardottir, Joanne M Murabito, Isaacs, WB, Elliott, KS, Bamlet, WR, Freddie C. Hamdy, Macgregor, S, Freddie C Hamdy, Grönberg, Henrik, Carvajal-Carmona, L, Gaborieau, Valerie, Easton, Douglas F., Lemire, M, Rafnar, T, Simon N. Stacey, Olson, SH, Amundadottir, Laufey, Chanock, SJ, Cotterchio, M, Muir Kenneth, Stephen J. Chanock, Australian Melanoma Family Study Investigators, Ioannidis John P. A., Margaret R. Spitz, Thorlacius, S, Stacey, Simon N, Tomlinson, Ian P M, Spitz Margaret R., Ioannidis, John P A, Brennan Paul, Steinunn Thorlacius, Mark I McCarthy, Lacroix, A, Paul Brennan, David J. Hunter, Patrick Sulem, William B. Isaacs, Brennan, P, Hwang Shih-Jen, Brown, Kevin M, Douglas F Easton, Daniel F Gudbjartsson, Zheng, W, Katherine S. Elliott, Gudbjartsson, Daniel Fannar, Thorunn Rafnar, Bas Bueno-De-Mesquita, H, Hamdy, Freddie, Boutron-Ruault, MC, Gudbjartsson, Daniel F., Tomlinson, Ian P.M., Zanke, Brent, Macgregor Stuart, Barkardottir Rosa B., Amos, Christopher I., Murabito, Joanne M, Jacobs, KB, Australian, MFSI, Brennan, Paul, Peeters, PHM, Spitz, MR, Kaaks, R, Eeles, Rosalind A., Ian P M Tomlinson +280 morecore +1 more sourceAdvancing conservation breeding programs for marine invertebrates
Conservation Biology, EarlyView.Abstract
In the face of ecosystem change and biodiversity loss caused by climate change and other stressors, conservation breeding, or captive breeding, with the aim of reintroduction for wild population recovery, is an emerging tool for preventing species’ extinction and rehabilitating ecosystems.Elora H. López‐Nandam, Bart Shepherd, Kylie Lev, Rebecca Albright +3 morewiley +1 more source
