Results 151 to 160 of about 5,719,995 (296)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Modifiable lifestyle factors and 4.9-Year changes in phenotypic age in the Taiwan biobank. [PDF]

Front Aging
Lin WY.
europepmc   +1 more source

Age & opportunity guidelines for working with older people in the arts: a resource for Bealtine organisers and others involved in the arts and older people [PDF]

, 2006
Moloney, Orla
core  

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Association between the Framingham steatosis index and osteoarthritis: evidence of mediation by phenotypic age. [PDF]

Sci Rep
Guo T, Zhang W, Zhao C, Bai J, Yu Y.
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Phenotypic age acceleration and genetic risk synergistically increase age-related eye disease risk in the UK Biobank. [PDF]

Sci Rep
Yuan H, Hu Y.
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Joint association of the frailty index and phenotypic age with all-cause and cause-specific mortality: A prospective cohort study. [PDF]

J Transl Int Med
Shao Z, Zhao Y, Yang H, Xiao M, Song M, Liao C, Pang Y, Gao W, Huang T, Yu C, Li S, Qi L, Li L, Lv J, Sun D.   +14 more
europepmc   +1 more source

Concrete-cement age.

, 1912
Title from cover.Industrial arts indexIssues for includes a supplement called: Cement mill section, issued also as a section of: Cement mill edition of Concrete-cement age.Mode of access: Internet.Continued in Jan.

core