Results 71 to 80 of about 5,719,995 (296)

Prenatal maternal effects on body condition score, female fertility, and milk yield of dairy cows [PDF]

open access: yes, 2007
In this study, maternal effects were described as age of dam at first and second calving, first-lactation body condition score (BCS) of the dam during gestation, and milk yield of the dam.
Brotherstone, S.   +5 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Association Between Estimated Glucose Disposal Rate and Biological Aging Among U.S. Adults: A Cross‐Sectional Study

open access: yesHealth Science Reports
Background and Aims Biomarkers of biological aging, including homeostatic dysregulation (HD), Klemera–Doubal method biological age (KDM‐BA), and phenotypic age (PA), provide multidimensional quantification of the aging process.
Mengjie Zhao   +5 more
doaj   +1 more source

Association of accelerated biological aging with kidney stone: Insights from the U.S. National health and nutrition examination survey

open access: yesPreventive Medicine Reports
Objective: Biological age is a more accurate measure of aging than chronological age. This study examines the association between biological age and the prevalence of kidney stones. Methods: Data were sourced from the U.S.
Yi Su   +4 more
doaj   +1 more source

Influence of Age of Onset on Huntington’s Disease Phenotype

open access: yesTremor and Other Hyperkinetic Movements, 2020
Older patients with Huntington's disease (HD) are often thought to have a slower progressing disease course with less behavioral symptoms than younger patients. However, phenotypic differences based on age of onset have not been well characterized in a large HD population.
Kwa, Lauren   +3 more
openaire   +3 more sources

Age & Opportunity annual report 2011

open access: yes, 2012
Strategic report for Age & Oppertunity ...
Age & Opportunity
core  

Relationship between Phenotypic Age, chronological age, and PhenoAgeAccel.

open access: yes, 2018
(A) As expected, Phenotypic Age was highly correlated with chronological age, partially due to the fact that it includes chronological age. The red line depicts the expected Phenotypic Age for each chronological age, with points above the line depicting ...
Luigi Ferrucci (150038)   +5 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Non headache phenotypes in pediatric age [PDF]

open access: yesThe Journal of Headache and Pain, 2015
Although headache represents the main symptom of migraine, it is a very complex disease and can be manifested by a number of other symptoms. This is particularly evident in pediatric age where clinical conditions different from headache can involve children who are already suffering or will suffer from migrainous headache.
openaire   +2 more sources

Phenotypic and genotypic analyses to guide selection of reverse transcriptase inhibitors in second-line HIV therapy following extended virological failure in Uganda. [PDF]

open access: yes, 2014
We investigated phenotypic and genotypic resistance after 2 years of first-line therapy with two HIV treatment regimens in the absence of virological ...
Awio, P.   +24 more
core   +1 more source

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