Results 111 to 120 of about 5,699,048 (257)

Association between phenotypic age and mortality risk in individuals with obesity: a retrospective cohort study

Frontiers in Public Health
ObjectiveThis study investigates the association between phenotypic age acceleration (PAA) and all-cause and cause-specific mortality in obese individuals.MethodsData were drawn from the National Health and Nutrition Examination Survey (NHANES) between ...
Yingxuan Huang, Apei Zhou, Yisen Huang, Yubin Wang, Xiaobo Liu, Xiaoqiang Liu   +5 more
doaj   +1 more source

Phenotypic age acceleration through a lens of intersectional inequalities in the German national cohort (NAKO)

Annals of Epidemiology
ABSTRACT Background Differences in biological aging have been linked to sociodemographic characteristics, but how multiple social inequalities intersect to shape biological aging differences across population subgroups remains unclear.
Enrique Alonso-Perez, Julie Lorraine O’Sullivan, Georg Fuellen, Paul Gellert, Henrik Rudolf   +4 more
openaire   +2 more sources

Increased rate of acceleration on Pine Island Glacier strongly coupled to changes in gravitational driving stress [PDF]

, 2009
Pine Island Glacier, Antarctica, has been undergoing several related changes for at least two decades; these include acceleration, thinning and grounding line retreat.
Scott, J. B. T., Vaughan, D G, Bingham, R. G., R. G. Bingham, Pritchard, H.D., Vaughan, D. G., Bingham, R.G., Pritchard, Hamish D., Scott, J.B.T., Smith, A. M., Vaughan, D.G., Pritchard, H. D., J. B. T. Scott, Gudmundsson, G H, Smith, A M, Pritchard, H D, Smith, A.M., Gudmundsson, G.H., D. G. Vaughan, Vaughan, David G., G. H. Gudmundsson, Scott, J B T, H. D. Pritchard, Bingham, R G, Gudmundsson, G. H., Gudmundsson, Hilmar, A. M. Smith, Bingham, Robert G.   +27 more
core   +2 more sources

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Association of accelerated biological aging with kidney stone: Insights from the U.S. National health and nutrition examination survey

Preventive Medicine Reports
Objective: Biological age is a more accurate measure of aging than chronological age. This study examines the association between biological age and the prevalence of kidney stones. Methods: Data were sourced from the U.S.
Yi Su, Zhao Hu, Houxian Liu, Lifeng Yao, Sui Yu   +4 more
doaj   +1 more source

Demo 06-01 Angular Acceleration Machine

, 2001
This device illustrates the application of the rotational analog of Newton's second law, t = I a. Two weights can be positioned symmetrically along an arm that rotates in a vertical plane around its center, varying the moment of inertia of the rotating

core  

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi, Sola Al Ghazal, Salem Hannoun, Medhat A. Siddik, Nour M. Najjar, Jim Dagher, Joseph Abboud, Myriam G. Semaan, Samia J. Khoury   +8 more
wiley   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source