Pigment‐associated cellular features, such as melanin levels and organelles, can be quantified in live cells with label‐free multimodal imaging. Quantitative phase imaging (cyan) measures cell mass, scattering (yellow) reports organelle content, including melanosomes, and absorbance imaging (magenta) captures pigment such as melanin.
Rebecca G. Zitnay +8 more
wiley +1 more source
Melanin pathway genes drive skin color divergence in juvenile blood parrot cichlid hybrids
The blood parrot cichlid (Cichlasoma citrinellum × C. synspilum), a hybrid of two distinct cichlid fish, is a popular ornamental fish. Its red appearance, achieved through its initial black coloration fading three weeks after hatching, is a ...
Chunyan Li +7 more
doaj +1 more source
The Effect of Hair Color on the Incorporation of Codeine into Human Hair [PDF]
The influence of melanin on the binding of xenobiotics in hair will impact the interpretation of drug concentrations determined by hair testing. The purpose of this study was to determine if codeine, as a model compound of abused drugs, would be ...
Augsburger, Marc P. +7 more
core
Ultrafast Molecular Spectroscopy Using a Hollow-Core Photonic Crystal Fibre Light Source [PDF]
We demonstrate, for the first time, the application of rare-gas filled hollow-core photonic crystal fibres (HC-PCFs) as tuneable ultraviolet light sources in femtosecond pump-probe spectroscopy.
Belli, Federico +6 more
core +2 more sources
Genetic Pigmentary Disorders: From Molecular Mechanisms to Clinical Manifestations
ABSTRACT Genetic pigmentary disorders represent a diverse group of genetic conditions characterized by alterations in melanin production and transport and melanocyte development, resulting from single‐gene pathological variants. These disorders encompass both hypopigmentary and hyperpigmentary phenotypes, affecting not only skin pigmentation but also ...
Ken Okamura, Tamio Suzuki
wiley +1 more source
Quantitative Analysis of Eumelanin and Pheomelanin in Hair and Melanomas
In this study, a method is provided for analyzing quantitatively the content and the class of melanin pigments in the tissues, e.g., hair and melanoma. The method is simple and rapid because it does not require the isolation of melanins from the tissues. The rationale was that permanganate oxidation of eumelanin yields pyrrole-2,3,5-tricarboxylic acid (
Ito, Shosuke, Jimbow, Kowichi
openaire +2 more sources
Germline MC1R status influences somatic mutation burden in melanoma [PDF]
The major genetic determinants of cutaneous melanoma risk in the general population are disruptive variants (R alleles) in the melanocortin 1 receptor (MC1R) gene.
A Ozola +45 more
core +1 more source
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Department of Chemical EngineeringLignin peroxidase is promising ingredient for skin whitening cosmetics because it is capable of oxidizing melanin with high redox potential.
Sung, Ho Joon
core
Application of Vitamin C in Melasma: A Meta‐Analysis and Systematic Review
Melasma is a chronic acquired facial hyperpigmentation disorder that remains a persistent clinical challenge due to its high recurrence rate and lack of a definitive cure. It imposes a substantial psychological burden on affected individuals, often leading to significant impairment of health‐related quality of life.
Lincen He, Sebastian Yu
wiley +1 more source
Pheomelanin as well as Eumelanin Is Present in Human Epidermis
There are two types of melanin in mammals, the brownish black eumelanin and the reddish yellow pheomelanin. Eumelanin and pheomelanin are present in human hair and this study was carried out to see whether both pigments are also present in human epidermis.
Thody, Anthony J +5 more
openaire +2 more sources

