Results 161 to 170 of about 3,468 (208)

Insights into lysosome-related organelle biogenesis: melanosome as a model organelle. [PDF]

Front Cell Dev Biol
Barral DC, Delevoye C, Larue L, Seabra MC, Raposo G, Setty SRG.   +5 more
europepmc   +1 more source

Retinal Vulnerability to Light Pollution in Vitiligo: A Narrative Review of the Role of Melanin Loss in Ocular Phototoxicity.

Dermatology
Contin MA, Bruera MG, Mat Nor MN, Acosta ML.   +3 more
europepmc   +1 more source

A review of therapies for hyperpigmentation modulating the synthesis of eumelanin to pheomelanin

Archives of Dermatological Research
There are significant psychosocial burdens in patients with hyperpigmentation, which emphasizes the importance of treatment. Current gold standard for treatment is hydroquinone; however, alternatives have been developed given the concern for side effects of hydroquinone.
Maria L Espinosa, Henry W Lim, Tasneem F Mohammad   +2 more
exaly   +4 more sources

Increase of the benzothiazole moiety content of pheomelanin pigment after endogenous free radical inducement

Dyes and Pigments, 2020
Pheomelanin, the sulfurated form of melanin pigment, is known to produce reactive oxygen species (ROS) and oxidative stress-mediated cytotoxicity. Previous studies have shown a conversion of the benzothiazine moiety of pheomelanin to the benzothiazole ...
Sol Rodríguez-Martínez, Kazumasa Wakamatsu, Ismael Galvan   +2 more
exaly   +2 more sources

Gas chromatography–mass spectrometry analysis of pheomelanin degradation products

Journal of Chromatography A, 2009
Melanoma is most rapidly increasing in the white population and people with pheomelanin skin type are at high risk to develop melanoma. However, little is known about the pheomelanin structure and function, and further elucidation of this melanin is ...
Dzeneta Nezirević Dernroth
exaly   +2 more sources

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Biosynthetic and structural studies on pheomelanin

BBA - Proteins and Proteomics, 1987
13C-NMR spectroscopy of pheomelanin biopolymers, prepared from isotopically enriched precursors, has been developed as a tool for structure elucidation of melanins. By employing large pulse-widths and short cycle time, only the signals originating from labeled carbons are observed in the high-resolution spectra of these polymers.
Miles R Chedekel
exaly   +3 more sources

DOPA pheomelanin is increased in nigral neuromelanin of Parkinson’s disease

Progress in Neurobiology, 2023
Neuromelanin (NM) in dopaminergic neurons of human substantia nigra (SN) has a melanic component that consists of pheomelanin and eumelanin moieties and has been proposed as a key factor contributing to dopaminergic neuron vulnerability in Parkinson's disease (PD).
Cai W, Wakamatsu K, Zucca FA, Wang Q, Yang K, Mohamadzadehonarvar N, Srivastava P, Tanaka H, Holly G, Casella L, Ito S, Zecca L, Chen X   +12 more
exaly   +5 more sources

How does pheomelanin synthesis contribute to melanomagenesis? [PDF]

BioEssays, 2013
Recently, we reported that melanoma risk in redheads is linked not only to pale skin, but also to the synthesis of the pigment – called pheomelanin – that gives red hair its color. We demonstrated that pheomelanin synthesis is associated with increased oxidative stress in the skin, yet we have not uncovered the chemical pathway between the molecule ...
David E Fisher
exaly   +3 more sources

Spectrophotometric Characterization of Eumelanin and Pheomelanin in Hair

Pigment Cell Research, 1996
Mammalian melanins exist in two chemically distinct forms: the brown to black eumelanins and the yellow to reddish‐brown pheomelanins. They can be quantified by HPLC analysis of pyrrole‐2,3,5‐tricarboxylic acid (PTCA) and aminohydroxyphenylalanine (AHP).
H, Ozeki, S, Ito, K, Wakamatsu, A J, Thody   +3 more
openaire   +4 more sources