Results 71 to 80 of about 244 (83)

PHGDH promotes esophageal squamous cell carcinoma progression via Wnt/β-catenin pathway

Cellular Signalling, 2023
Xiaoxuan Duan, Xiaoshuo Dai, Wenbo Cao   +2 more
exaly  

Discovery of PHGDH inhibitors by virtual screening and preliminary structure–activity relationship study

Bioorganic Chemistry, 2022
Cheng Huang, Guo-Qiang Lin, Ping Tian
exaly  

The NMDA receptor activation by d -serine and glycine is controlled by an astrocytic Phgdh-dependent serine shuttle

Proceedings of the National Academy of Sciences of the United States of America, 2019
Inna Radzishevsky, Francesco Marchesani, Marialaura Marchetti   +2 more
exaly  

Downregulation of PHGDH expression and hepatic serine level contribute to the development of fatty liver disease

Metabolism: Clinical and Experimental, 2020
Hyungtai Sim, Kang-Yo Lee, You-Jin Choi   +2 more
exaly  

The NAD+ Salvage Pathway Supports PHGDH-Driven Serine Biosynthesis

Cell Reports, 2018
Michael A Giacomantonio, João A Paulo, Barry E Kennedy   +2 more
exaly  

Rational Design of Selective Allosteric Inhibitors of PHGDH and Serine Synthesis with Anti-tumor Activity

Cell Chemical Biology, 2017
Qian Wang, Maria V Liberti, Jason W Locasale   +2 more
exaly  

Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells

Cell Metabolism, 2018
Charlotte Dubois, Joanna Kalucka, Mark R Sullivan   +2 more
exaly  

High level PHGDH expression in breast is predominantly associated with keratin 5‐positive cell lineage independently of malignancy

Molecular Oncology, 2015
Irina Gromova, Pavel Gromov, Naoko Honma   +2 more
exaly  

Transcriptional regulation by PHGDH drives amyloid pathology in Alzheimer’s disease

Cell
Wenxin Zhao, Sheng Zhong
exaly  

Targeting PHGDH reverses the immunosuppressive phenotype of tumor-associated macrophages through α-ketoglutarate and mTORC1 signaling

Cellular and Molecular Immunology
Zhengnan Cai, Sonja Hager, Jayne Louise Wilson   +2 more
exaly