Results 31 to 40 of about 4,025 (191)

Incorporation of biguanide compounds into poly(GL)-b-poly(GL-co-TMC-co-CL)-b-poly(GL) monofilament surgical sutures [PDF]

, 2017
A new biodegradable coating was developed for bioabsorbable monofilament sutures. Specifically, a random copolymer having 35 wt-% and 65 wt-% of lactide and trimethylene carbonate units showed appropriate flexibility, stickiness and degradation rate, as ...
Cabral, Tània, Franco García, María Lourdes, Lorenzetti, Alice, Marquez, Yolanda, Puiggalí Bellalta, Jordi, Turón Dols, Pau, Valle Mendoza, Luis Javier del   +6 more
core   +2 more sources

Self-Assembled PHMB Titanium Coating Enables Anti-Fusobacterium nucleatum Strategy [PDF]

Coatings, 2021
Fusobacterium nucleatum (F. nucleatum) is a gram-negative obligate anaerobe bacterium that threatens human periodontal health. It can cause many oral diseases, including periodontitis, gingivitis and peri-implantitis, and even some diseases such as colorectal cancer are related to it.
Jiangyuan Zhao, Shixin Jin, António HS Delgado, Zhuofan Chen, Jukka Pekka Matinlinna, James Kit-Hon Tsoi   +5 more
openaire   +1 more source

Raman Microspectroscopy Analysis in the Treatment of Acanthamoeba Keratitis [PDF]

, 2013
Acanthamoeba keratitis is a rare but serious corneal disease, often observed in contact lens wearers. Clinical treatment of infected patients frequently involves the use of polyhexamethylene biguanide (PHMB), a polymer used as a disinfectant and ...
Capriglione, P, Cennamo, G, Cerulli, L, Del Prete, S, Di Cave, D, Pesce, G, Rusciano, G, Sasso, A   +7 more
core   +8 more sources

Polyhexanide as a new antiseptic composition for a dentist

Эндодонтия Today, 2021
Aim. To assess systematically the available scientific evidence about clinical response of using polyhexanide as an antiseptic agent in medicine and dentistry.
Z. S. Khabadze, D. S. Nazarova, A. A. Kulikova, Yu. A. Generalova, E. S. Shilyaeva, A. P. Kotelnikova   +5 more
doaj   +1 more source

Targeting the hard to reach: Challenges and novel strategies in the treatment of intracellular bacterial infections: Targeting intracellular bacteria [PDF]

, 2016
Infectious diseases continue to threaten human and animal health and welfare globally, impacting millions of lives and causing substantial economic loss. The use of antibacterials has been only partially successful in reducing disease impact.
Good, L, Kamaruzzaman, N F, Kendall, S L
core   +1 more source

Polyhexamethylene Biguanide and Nadifloxacin Self-Assembled Nanoparticles: Antimicrobial Effects against Intracellular Methicillin-Resistant Staphylococcus aureus [PDF]

, 2018
The treatment of skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus (MRSA) remains a challenge, partly due to localization of the bacteria inside the host’s cells, where antimicrobial penetration and efficacy is limited.
Chivu, A, de Fatima Pina, M, Good, L, Kamaruzzaman, N F   +3 more
core   +3 more sources

The Effects of Polyhexamethylene Biguanide (PHMB) and TLR Agonists Alone or as Polyplex Nanoparticles against Leishmania infantum Promastigotes and Amastigotes

Veterinary Sciences, 2020
Dogs are the main reservoir for Leishmania infantum, manifesting from a subclinical to a fatal disease. Limited treatments are available, although new antiparasitics and immunomodulators are pursued.
Pamela Martínez-Orellana, Marta Baxarias, Liam Good, Laia Solano-Gallego   +3 more
doaj   +1 more source

Efficacy of 0.2% povidone-iodine and 0.1% polyhexamethylene biguanide as preoperative antiseptics in equine ophthalmic procedures. [PDF]

Vet Ophthalmol
Abstract Objective This retrospective study evaluates the efficacy of povidone‐iodine (PI) and polyhexamethylene biguanide (PHMB) as preoperative antiseptics in equine ophthalmic procedures. Animals Studied Horses that underwent routine ophthalmic surgery and procedures.
Farkas A, Thieme K, Soimala T, Jensen CK, Eule JC.   +4 more
europepmc   +2 more sources

Bacterial Growth Kinetics under a Novel Flexible Methacrylate Dressing Serving as a Drug Delivery Vehicle for Antiseptics [PDF]

, 2013
A flexible methacrylate powder dressing (Altrazeal®) transforms into a wound contour conforming matrix once in contact with wound exudate. We hypothesised that it may also serve as a drug delivery vehicle for antiseptics.
Archibald, Assadian, Axel Kramer, Beldon, Braga, Chen, Christina Forstner, Clark, Cutting, David Leaper, Deitch, Disemond, Eberlein, Fang, Fitzgerald, Henry-Stanley, Hirsch, Johannes Leitgeb, Keith Cutting, Kim, Lalani, Leaper, Leaper, Migliaresi, Minnich, Nathan, Nordmann, Ojan Assadian, Rupert Schuster, Sibbald, Tsou, Vanscheidt, Verena Dosch, Wang, Winter   +34 more
core   +4 more sources

Evaluation of Polyhexamethylene Biguanide (PHMB) as a Disinfectant for Adenovirus [PDF]

JAMA Ophthalmology, 2013
Swimming pools can be a vector for transmission of adenovirus ocular infections. Polyhexamethylene biguanide (PHMB) is a disinfectant used in swimming pools and hot tubs.To determine whether PHMB is an effective disinfectant against ocular adenovirus serotypes at a concentration used to disinfect swimming pools and hot tubs.In vitro laboratory study ...
Eric G, Romanowski, Kathleen A, Yates, Katherine E, O'Connor, Francis S, Mah, Robert M Q, Shanks, Regis P, Kowalski   +5 more
openaire   +2 more sources