Results 51 to 60 of about 4,025 (191)

Effect of Local Administration of Meglumine Antimoniate and Polyhexamethylene Biguanide Alone or in Combination with a Toll-like Receptor 4 Agonist for the Treatment of Papular Dermatitis due to Leishmania infantum in Dogs

Pathogens, 2023
Papular dermatitis is a cutaneous manifestation of canine Leishmania infantum infection associated with mild disease. Although it is a typical presentation, nowadays, there is still no established treatment.
Icíar Martínez-Flórez, Maria Jose Guerrero, Annabel Dalmau, Maria Cabré, Maria Magdalena Alcover, Diana Berenguer, Liam Good, Roser Fisa, Cristina Riera, Laura Ordeix, Laia Solano-Gallego   +10 more
doaj   +1 more source

Variable effects of exposure to formulated microbicides on antibiotic susceptibility in firmicutes and proteobacteria [PDF]

, 2016
Microbicides are broad-spectrum antimicrobial agents that generally interact with multiple pharmacological targets. While they are widely deployed in disinfectant, antiseptic, and preservative formulations, data relating to their potential to select for ...
Amézquita, Alejandro, Cowley, Nicola L., Drake, H. L., Forbes, Sarah, Humphreys, Gavin, Knight, Christopher G., McBain, Andrew J., McClure, Peter   +7 more
core   +1 more source

Safety of intrastromal injection of polyhexamethylene biguanide and propamidine isethionate in a rabbit model

Journal of Advanced Research, 2020
Acanthamoeba keratitis (AK) is difficult to treat, especially when the corneal deep stroma is involved. Intrastromal injection of antimicrobial agents is an effective adjuvant therapy for deep recalcitrant microbial keratitis; however, it has not been ...
Chen-Chee Lim, I-Chen Peng, Yi-Hsun Huang   +2 more
doaj   +1 more source

A Systematic Comparison of Antimicrobial Wound Dressings using a Planktonic Cell and an Immobilised Cell Model. Kamran [PDF]

, 2015
Aim: The aim of the study was to evaluate the ability of in-vitro planktonic and immobilised cell models for determining the antimicrobial efficacy of common antimicrobial wound dressings.
Abdelrahman, Agren, Alandejani, Asavavisithchai, Barrett, Brackman, Brackman, Bradshaw, BSI, BSI, BSI, Castellano, Chopra, Donlan, Durante, Eberlein, Fong, French, Gallant-Behm, Herruzo, Hill, Ip, Kucera, Lindsay, Lu, Merckoll, Moore, Mullai, O'Shea, Olaitan, Ovington, Parsons, Rasmussen, Sebeny, Stephen-Haynes, Thomas, Thorn, Tkachenko, Toit, Turton, White, Wild   +41 more
core   +2 more sources

Die Aufnahme von PHMB in epicitehydro(R)

, 2019
Einleitung: Die stetige Zunahme von Antibiotikaresistenzen ist besonders für VerbrennungspatientInnen relevant, da diese oft sehr große Wundflächen aufweisen und oft mit Wundinfektionen zu kämpfen haben. 43% der Verbrennungspezialisten aus der ganzen Welt sind sich einig, dass[zum vollständigen Text gelangen Sie über die oben angegebene URL]
Holzer, JCJ, Tuca, AC, Bernadelli de Mattos, I, Groeber-Becker, F, Funk, M, Popp, D, Mautner, S, Birngruber, T, Kamolz, LP   +8 more
openaire   +1 more source

Effects of formulation on microbicide potency and mitigation of the development of bacterial insusceptibility [PDF]

, 2015
Risk assessments of the potential for microbicides to select for reduced bacterial susceptibility have been based largely on data generated through the exposure of bacteria to microbicides in aqueous solution.
Amézquita, Alejandro, Cowley, Nicola L., Drake, H. L., Forbes, Sarah, Humphreys, Gavin J., McBain, Andrew J., McClure, Peter   +6 more
core   +1 more source

Determination of polyhexamethylene biguanide hydrochloride

Reviews in Analytical Chemistry, 2014
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely used as a disinfectant in personal care products such as cosmetics and toiletries and as a sanitizer in swimming pools. PHMB-HCl possesses marked characteristics of cationic polyelectrolytes.
Masadome Takashi, Hattori Toshiaki
doaj   +1 more source

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

Loss of Function in Escherichia coli exposed to Environmentally Relevant Concentrations of Benzalkonium Chloride [PDF]

, 2018
Assessing the risk of resistance associated with biocide exposure commonly involves exposing microorganisms to biocides at concentrations close to the MIC. With the aim of representing exposure to environmental biocide residues, MG1655 was grown for 20
Bloomfield SF, Chuanchuen R, European Committee for Antimicrobial Susceptibility Testing of the European Society of Clinical Microbiology and Infectious Diseases, Gilbert P, Girón JA, Grillitsch B, Heir E, Klimek JW, Kümmerer K, Langsrud S, Maki DG, Nagai K   +11 more
core   +8 more sources

Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects

Advanced Healthcare Materials, EarlyView.
Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.
Ayden Watt, Chably Rachella, Charlotte Jaloux, Joshua Vorstenbosch, Adam Hart, Michael Tanzer, Geraldine Merle, Jake Barralet   +7 more
wiley   +1 more source