Results 121 to 130 of about 2,579,257 (273)

The transcription factor PHR1 plays a key role in the regulation of sulfate shoot-to-root flux upon phosphate starvation in Arabidopsis

BMC Plant Biology, 2011
Background Sulfate and phosphate are both vital macronutrients required for plant growth and development. Despite evidence for interaction between sulfate and phosphate homeostasis, no transcriptional factor has yet been identified in higher plants that ...
Arpat Bulak, Secco David, Rouached Hatem, Poirier Yves   +3 more
doaj   +1 more source

Single‐Cell Resolution Mapping of Osteoarthritis‐Associated Chondrocyte Dynamics Using a High‐Density CMOS MEA Platform

Advanced Healthcare Materials, EarlyView.
Single‐cell and spatially resolved impedance mapping using a high‐density CMOS‐MEA platform enables non‐invasive monitoring of osteoarthritis‐associated chondrocyte dynamics. Continuous label‐free measurements reveal heterogeneous remodeling behaviors, including proliferation, migration, and phenotypic transitions, establishing a powerful approach for ...
Neha Deshpande, Pauline Coquart, Bram Theuns, Susanne Cremery, Jaime Rodolfo V. Garcia III, Julien Verplanken, Dennis Lambrechts, Dries Braeken, Liesbet Lagae, Johanna Bolander   +9 more
wiley   +1 more source

Bone-kidney-endocrine axis in nephrolithiasis and crystalluria

Mìžnarodnij Endokrinologìčnij Žurnal
Background. Nephrolithiasis (NL) is a common polyetiological urological disease with multifactorial pathogenesis. In recent years, increasing attention has been paid to the association between NL and alterations in bone mineral density (BMD ...
O.D. Nikitin, I.A. Kordubailo, O.I. Nishkumay, H.D. Reznikov, Mike K.S. Chan   +4 more
doaj   +1 more source

Molecular genetics of phosphate homeostasis.

, 2015
Phosphate homeostasis is crucial for manifold physiological processes. Within the so-called bone-kidney axis, bone-derived FGF23 has emerged as the key regulator of systemic phosphate turnover. It controls, through activating FGFR/Klotho complexes in the
Diener, S.
core  

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

Advanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li, Chunbai Xiang, Ye Xu, Yu Liu, Keze Hong, Fanchu Zeng, Gelin Xu, Zhao‐Xi Wang, Jonathan L. Sessler, Ping Gong   +9 more
wiley   +1 more source

Acidocalcisome-like vacuoles constitute a feedback-controlled phosphate buffering system for the cytosol

eLife
Cells experience strong variations in the consumption and availability of inorganic phosphate (Pi). Since Pi is an essential macronutrient but excess Pi has negative impacts on nucleotide hydrolysis and metabolism, its concentration must be maintained in
Samuel Bru, Lydie Michaillat Mayer, Geun-Don Kim, Danye Qiu, Henning J Jessen, Andreas Mayer   +5 more
doaj   +1 more source

Effect of 16-weeks vitamin D replacement on calcium-phosphate homeostasis in overweight and obese adults

, 2019
Effect of 16-weeks vitamin D replacement on calcium-phosphate homeostasis in overweight and obese ...
K Wilson (8412285), R Scragg (13293810), David Scott (13093551), N Naderpoor (13379796), M Plebanski (10689075), M de Courten (13293333), Jakub Mesinovic (13074852), A Mousa (13451598), B de Courten (7723058)   +8 more
core  

Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution

Advanced Healthcare Materials, EarlyView.
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk, Vaidehi Londhe, Susanne Boye, Martin Müller, Carsten Werner, Manfred F. Maitz, Quinn A. Besford   +6 more
wiley   +1 more source

Roles of Pho regulon in bacterial pathogenicity

Virulence
Bacterial infections are a leading cause of global health loss. The prerequisites for bacteria to colonize and establish systemic infection in the host are environmental adaptability and the expression of virulence factors.
Jing Yang, Min Wang, Yi Wang, Rui Qiang, Qiyuan Jin, Chenhao Zhao, Qi Chen, Mingxiao Han, Xin Ma, Haifang Zhang   +9 more
doaj   +1 more source

Phosphate and zinc transport and signalling in plants: toward a better understanding of their homeostasis interaction

, 2014
Phosphate and zinc transport and signalling in plants: toward a better understanding of their homeostasis ...
Ghazanfar Abbas Khan (8703939), Zaigham Shahzad (250249), Pierre Berthomieu (113087), Nadia Bouain (5047583), Chedly Abdelly (580076), Yves Poirier (3296853), Hatem Rouached (5047571), Aida Rouached (19473442)   +7 more
core