Results 31 to 40 of about 47,232 (289)

Effect in supralethally irradiated rats of granulocyte colony- stimulating factor and lisofylline on hematopoietic reconstitution by syngeneic bone marrow or whole organ passenger leukocytes [PDF]

, 1997
We have previously shown the existence of migratory hematopoietic stem cells in adult solid organs. This study demonstrates that granulocyte colony- stimulating factor (G-CSF) and lisofylline, a phosphatidic acid inhibitor that suppresses hematopoiesis ...
Abdul Rao, Angus W. Thomson, Anthony J. Demetris, Berry, Bociek, Clarke, Fontes, Foster, Foster, Lieschke, Lyman, Masanobu Terakura, Moore, Murase, Murase, Noriko Murase, Qing Ye, Schuening, Singer, Starzl, Tanikawa, Thomas E. Starzl, Toshiki Sakamoto, Uckun   +23 more
core   +1 more source

An intracellular motif of GLUT4 regulates fusion of GLUT4-containing vesicles

BMC Cell Biology, 2008
Background Insulin stimulates glucose uptake by adipocytes through increasing translocation of the glucose transporter GLUT4 from an intracellular compartment to the plasma membrane.
Welsh Gavin I, Leney Sophie E, Pettitt Trevor R, Heyward Catherine A, Tavaré Jeremy M, Wakelam Michael JO   +5 more
doaj   +1 more source

Cellular phosphatidic acid sensor, α-synuclein N-terminal domain, detects endogenous phosphatidic acid in macrophagic phagosomes and neuronal growth cones

Biochemistry and Biophysics Reports, 2020
Phosphatidic acid (PA) is the simplest phospholipid and is involved in the regulation of various cellular events. Recently, we developed a new PA sensor, the N-terminal region of α-synuclein (α-Syn-N).
Haruka Yamada, Fumi Hoshino, Qiang Lu, Fumio Sakane   +3 more
doaj   +1 more source

Comprehensive analysis of glycerolipid dynamics during tobacco pollen germination and pollen tube growth

Frontiers in Plant Science, 2022
Pollen germination and subsequent pollen tube elongation are essential for successful land plant reproduction. These processes are achieved through well-documented activation of membrane trafficking and cell metabolism. Despite this, our knowledge of the
Natalia Serrano, Přemysl Pejchar, Hana Soukupová, Martin Hubálek, Martin Potocký   +4 more
doaj   +1 more source

Identification of caspase 3 motifs and critical aspartate residues in human Phospholipase D1b and Phopsholipase D2a [PDF]

, 2008
Stimulation of mammalian cells frequently initiates phospholipase D-catalysed hydrolysis of phosphatidylcholine in the plasma membrane to yield phosphatidic acid (PA) a novel lipid messenger.
Ahn, Avila-Flores, Brown, Cazzolli, Chen, Cross, Degterev, Du, Earnshaw, Farquhar, Fisher, Graham Ladds, Guimaraes, Hodgkin, Hui, Iwasaki-Bessho, Kasai, Kusner, Lim, Matthew N. Hodgkin, McDermott, Michelle H. Wright, Michelle J. Farquhar, Mina-olga Aletrari, Nakashima, Nozawa, Oh, O’Luanaigh, Palicz, Park, Ponting, Powner, Powner, Rozengurt, Samejima, Shi, Timmer, Wissing, Xie, Yamada, Zeniou-Meyer, Zhao, Zheng, Zhong   +43 more
core   +1 more source

Fat metabolism in higher plants: XIII. phosphatidic acid synthesis and diglyceride phosphokinase activity in mitochondria from peanut cotyledons*

Journal of Lipid Research, 1960
A phosphatidic acid is the major lipid to become labeled when Pi32 (inorganic orthophosphate labeled with P32), under conditions of oxidative phosphorylation, or ATP32 is fed to mito-choline and phosphatidylethanolamine in the mitochondria obtained a ...
Clive Bradbeer, P.K. Stumpf
doaj   +1 more source

Phosphatidic acid inhibits SCAB1-mediated F-actin bundling in Arabidopsis

Plant Signaling & Behavior, 2023
Stomatal closure-associated actin-binding protein 1 (SCAB1) regulates stomatal closure by mediating actin filament reorganization in Arabidopsis thaliana.
Haiqi Fu, Xinhao Yang, Rong Hao, Xiuli Han, Shu Song, Yan Guo, Yongqing Yang   +6 more
doaj   +1 more source

Inositols in Insulin Signaling and Glucose Metabolism [PDF]

, 2018
In the past decades, both the importance of inositol for human health and the complex interaction between glucose and inositol have been the subject of increasing consideration. Glucose has been shown to interfere with cellular transmembrane transport of
Bevilacqua, Arturo, Bizzarri, Mariano
core   +1 more source

Recent advances in expanding the coverage of the lipidome [PDF]

, 2017
The lipidome comprises a large array of molecules with diverse physicochemical properties. Lipids are structural components of cells, act as a source of energy, and function as signaling mediators.
Kamphorst, Jurre J., Tumanov, Sergey
core   +1 more source

A rapid and sensitive radiochemical assay for phosphatidic acid phosphohydrolase activity

Journal of Lipid Research, 1977
A technique is described for the radiochemical assay of phosphatidic acid phosphohydrolase activity in rat brain. Radiochemically pure 32P-labeled phosphatidic acid of known specific radioactivity and structure, which was biosynthesized in vitro by the ...
T J Flynn, D S Deshmukh, R A Pieringer
doaj   +1 more source