Results 121 to 130 of about 30,263 (277)

Phosphatidylethanol in post‐mortem blood: A comparative study of blood matrices and its stability at routine storage conditions

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Determination of alcohol markers in post‐mortem cases can be useful to classify drinking habits and potential alcohol habituation prior to death. Phosphatidylethanol (PEth) is a direct alcohol marker and is already commonly used in a variety of contexts.
Jeremai Hose   +4 more
wiley   +1 more source

Intestinal DHA-PA-PG axis promotes digestive organ expansion by mediating usage of maternally deposited yolk lipids

open access: yesNature Communications
Although the metabolism of yolk lipids such as docosahexaenoic acid (DHA) is pivotal for embryonic development, the underlying mechanism remains elusive.
Zhengfang Chen   +11 more
doaj   +1 more source

Reversible Nuclear-Lipid-Droplet Morphology Induced by Oleic Acid: A Link to Cellular-Lipid Metabolism [PDF]

open access: yes, 2017
Neutral lipidsÐinvolved in many cellular processesÐare stored as lipid droplets (LD), thosemainly cytosolic (cLD) along with a small nuclear population (nLD).
Garcia, Margarita Maria   +5 more
core   +3 more sources

Differential Effects of Liver Regeneration on Aging‐Related Changes in Gene Expression and Metabolic Function

open access: yesAging Cell, EarlyView.
The age‐specific gene expression status of aged mouse hepatocytes is mostly resolved and rejuvenated when liver regeneration is completed; whereas the age‐specific intracellular metabolic status detected in the liver of aged mice is largely maintained and not rejuvenated even after liver regeneration is completed.
Ryo Murayama   +9 more
wiley   +1 more source

Identification of Genes Affecting Vacuole Membrane Fragmentation in Saccharomyces cerevisiae. [PDF]

open access: yes, 2013
The equilibrium of membrane fusion and fission influences the volume and copy number of organelles. Fusion of yeast vacuoles has been well characterized but their fission and the mechanisms determining vacuole size and abundance remain poorly understood.
Mayer, A., Michaillat, L.
core   +3 more sources

Phosphatidic acid and lipid-sensing by mTOR [PDF]

open access: yesTrends in Endocrinology & Metabolism, 2013
Mammalian target of rapamycin (mTOR) has been implicated as a sensor of nutrient sufficiency for dividing cells and is activated by essential amino acids and glucose. However, cells also require lipids for membrane biosynthesis. A central metabolite in the synthesis of membrane phospholipids is phosphatidic acid (PA), which is required for the ...
openaire   +3 more sources

Novel approaches for the discovery of pharmacogenetic biomarkers of chemotoxicity in patients with colorectal cancer

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Chemotherapeutic treatment for colorectal cancer (colorectal cancer) allows for increased patient overall survival. However, current therapeutic regimens are often associated with the development of adverse drug reactions, which represent a morbidity, mortality and economic issue.
Ana Rita Simoes   +20 more
wiley   +1 more source

Multiple-Omics Techniques Reveal the Role of Glycerophospholipid Metabolic Pathway in the Response of Saccharomyces cerevisiae Against Hypoxic Stress

open access: yesFrontiers in Microbiology, 2019
Although the biological processes of organism under hypoxic stress had been elucidated, the whole physiological changes of Saccharomyces cerevisiae are still unclear. In this work, we investigated the changes of biological process of S.
Zhengchao Xia   +11 more
doaj   +1 more source

Lipid remodelling: unravelling the response to cold stress in Arabidopsis and its extremophile relative Eutrema salsugineum [PDF]

open access: yes, 2017
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License https://creativecommons.org/licenses/by/4.0/ Crown Copyright © 2017 Published by Elsevier Ireland Ltd.Environmental constraints limit
Barrero Sicilia, Cristina   +3 more
core   +1 more source

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