Results 61 to 70 of about 5,016,109 (334)

The effects of carboxylic acids on the aqueous dispersion and electrophoretic deposition of ZrO2 [PDF]

Journal of the European Ceramic Society, Volume 32, Issue 1, 2012, Pages 235-244, 2013
The agglomeration, electrokinetic properties and electrophoretic deposition behaviour of aqueous suspensions of ZrO2 with carboxylic acid additives were studied in comparison with conventional pH adjustment. It was found that citric acid imparted negative zeta-potential values and electrosteric stabilisation to particles in suspensions at all pH levels.
arxiv   +1 more source

Lipid sensing by mTOR complexes via de novo synthesis of phosphatidic acid

Journal of Biological Chemistry, 2017
mTOR, the mammalian target of rapamycin, integrates growth factor and nutrient signals to promote a transformation from catabolic to anabolic metabolism, cell growth, and cell cycle progression.
D. Menon, Darin Salloum, Elyssa Bernfeld, E. Gorodetsky, A. Akselrod, M. Frias, J. Sudderth, Pei-Hsuan Chen, R. Deberardinis, D. A. Foster   +9 more
semanticscholar   +1 more source

Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes [PDF]

, 2020
BACKGROUND: Naturally occurring variation in Membrane-bound O-acyltransferase domain-containing 7 (MBOAT7), encoding for an enzyme involved in phosphatidylinositol acyl-chain remodelling, has been associated with fatty liver and hepatic disorders.
Davidson, Nicholas O, et al,, Meroni, Marica   +2 more
core   +1 more source

Modulation of Membrane Curvature by Phosphatidic Acid and Lysophosphatidic Acid [PDF]

Traffic, 2003
The local generation of phosphatidic acid plays a key role in the regulation of intracellular membrane transport through mechanisms which are largely unknown. Phosphatidic acid may recruit and activate downstream effectors, or change the biophysical properties of the membrane and directly induce membrane bending and/or destabilization.
Ben de Kruijff, Koert N.J. Burger, Edgar E. Kooijman, Vladimir Chupin   +3 more
openaire   +4 more sources

Oleic Acid-Containing Phosphatidylinositol Is a Blood Biomarker Candidate for SPG28

Biomedicines, 2023
Hereditary spastic paraplegia is a genetic neurological disorder characterized by spasticity of the lower limbs, and spastic paraplegia type 28 is one of its subtypes.
Takuya Morikawa, Masatomo Takahashi, Yoshihiro Izumi, Takeshi Bamba, Kosei Moriyama, Gohsuke Hattori, Ryuta Fujioka, Shiroh Miura, Hiroki Shibata   +8 more
doaj   +1 more source

Stimulation of glucose utilization in 3T3 adipocytes and rat diaphragm in vitro by the sulphonylureas, glimepiride and glibenclamide, is correlated with modulations of the cAMP regulatory cascade [PDF]

, 1994
The long-term hypoglycemic activity of sulphonylurea drugs has been attributed, in part at least, to the stimulation of glucose utilization in extra-pancreatic tissues. The novel sulphonylurea, glimepiride, gives rise to a longer lasting reduction in the
Altan, Aoki, Avruch, Bak, Begum, Brown, Caren, Clancy, Cooper, Cushman, Daniels, Davidson, Farese, Feldman, Feldman, Gavin, Geisen, Gould, Guinovart, Hirshman, Honnor, Jacobs, Jacobs, Jacobs, James, James, Karnieli, Kirsch, Klip, Kolterman, Kono, Lane, Larner, Lawrence, Lawson, Lebovitz, Leichter, Maloff, Mandarino, Misek, Moody, Müller, Müller, Müller, Müller, Müller, Okuno, Oron, Osegawa, Panten, Popov, Putnam, Reusch, Rogers, Roskoski, Saltiel, Saltiel, Saltiel, Simonson, Smith, Solomon, Standing, Suissa, Suzuki, Tordjman, Towbin, Van Putten, Vila, Villalba, Wang, Wang, Wieland, Wray, Yalow, Zinman, Zuber   +75 more
core   +1 more source

Mitochondria and Endoplasmic Reticulum Contact Site as a Regulator of Proteostatic Stress Responses in Neurodegenerative Diseases

BioEssays, EarlyView.
Recent findings indicate that mitochondria‐associated membranes (MAMs), where the endoplasmic reticulum directly contacts the mitochondria, are a novel microdomain essential for cellular homeostasis, including proteostasis. We summarize the disruption of protein homeostasis and MAM alteration in neurodegenerative diseases, then discuss challenges and ...
Seiji Watanabe, Koji Yamanaka
wiley   +1 more source

Apicoplast-Localized Lysophosphatidic Acid Precursor Assembly Is Required for Bulk Phospholipid Synthesis in Toxoplasma gondii and Relies on an Algal/Plant-Like Glycerol 3-Phosphate Acyltransferase.

PLoS Pathogens, 2016
Most apicomplexan parasites possess a non-photosynthetic plastid (the apicoplast), which harbors enzymes for a number of metabolic pathways, including a prokaryotic type II fatty acid synthesis (FASII) pathway.
Souad Amiar, James I MacRae, Damien L Callahan, David Dubois, Giel G van Dooren, Melanie J Shears, Marie-France Cesbron-Delauw, Eric Maréchal, Malcolm J McConville, Geoffrey I McFadden, Yoshiki Yamaryo-Botté, Cyrille Y Botté   +11 more
doaj   +1 more source

Lipidomic analysis of immune activation in equine leptospirosis and Leptospira-vaccinated horses. [PDF]

PLoS ONE, 2018
Currently available diagnostic assays for leptospirosis cannot differentiate vaccine from infection serum antibody. Several leptospiral proteins that are upregulated during infection have been described, but their utility as a diagnostic marker is still ...
Paul L Wood, Margaret Steinman, Erdal Erol, Craig Carter, Undine Christmann, Ashutosh Verma   +5 more
doaj   +1 more source

Nature's Starships. I. Observed Abundances and Relative Frequencies of Amino Acids in Meteorites [PDF]

, 2014
The class of meteorites called carbonaceous chondrites are examples of material from the solar system which have been relatively unchanged from the time of their initial formation. These meteorites have been classified according to the temperatures and physical conditions of their parent planetesimals.
arxiv   +1 more source