Results 71 to 80 of about 30,263 (277)
PLoS Pathogens, 2016 Most apicomplexan parasites possess a non-photosynthetic plastid (the apicoplast), which harbors enzymes for a number of metabolic pathways, including a prokaryotic type II fatty acid synthesis (FASII) pathway.
Souad Amiar +11 more
doaj +1 more source
Molecular brakes regulating mTORC1 activation in skeletal muscle following synergist ablation [PDF]
, 2014 The goal of the current work was to profile positive (mTORC1 activation, autocrine/paracrine growth factors) and negative [AMPK, unfolded protein response (UPR)] pathways that might regulate overload-induced mTORC1 (mTOR complex 1) activation with the ...
Amy Patton +12 more
core +4 more sources
Targeting Seipin to Alleviate Hepatic Steatosis in Zebrafish (Danio Rerio)
Advanced Science, EarlyView.Seipin plays a crucial role in lipid metabolism. Seipin overexpression ameliorates high‐fat‐diet‐induced hepatic steatosis and enhances growth in zebrafish. Mechanistically, Seipin interacts with Plin2 to promote Plin2 degradation and enhances phosphatidylcholine synthesis via Seipin/CCTα/CHPT interactions.
Weijia Li +6 more
wiley +1 more source
Antioxidants, 2021 Non-nutritive sweeteners are widely used in food and medicines to reduce energy content without compromising flavor. Herein, we report that Rebaudioside A (Reb A), a natural, non-nutritive sweetener, can extend both the lifespan and healthspan of C ...
Pan Li +3 more
doaj +1 more source
Mechanistic target of rapamycin (mTOR) signaling genes in decapod crustaceans: cloning and tissue expression of mTOR, Akt, Rheb, and S6 kinase in the green crab, Carcinus maenas, and blackback land crab, Gecarcinus lateralis [PDF]
, 2014 Mechanistic target of rapamycin (mTOR) controls global translation of mRNA into protein by phosphorylating p70 S6 kinase (S6K) and eIF4E-binding protein-1. Akt and Rheb, a GTP-binding protein, regulate mTOR protein kinase activity. Molting in crustaceans
Abuhagr, Ali M. +3 more
core +2 more sources
A Sec14 domain protein is required for photoautotrophic growth and chloroplast vesicle formation in Arabidopsis thaliana. [PDF]
, 2020 In eukaryotic photosynthetic organisms, the conversion of solar into chemical energy occurs in thylakoid membranes in the chloroplast. How thylakoid membranes are formed and maintained is poorly understood.
Armbruster, Ute +6 more
core +2 more sources
Advanced Science, EarlyView.This study engineers Yarrowia lipolytica to produce succinic acid (SA) from lignocellulosic biomass. Adaptive evolution and multi‐omics analysis identify regulators that alleviate xylose metabolic disorder. Multi‐copy integration of xylose metabolic genes resolves redox imbalances from a futile fatty acid cycle, producing high‐titer SA from corn stover
Yutao Zhong +7 more
wiley +1 more source
Characterization of the total lipid and fatty acid composition of rat olfactory mucosa.
Journal of Lipid Research, 1989 Phospholipid accounted for 81% (by weight) of the total lipid of rat olfactory mucosa. Phosphatidylcholine (46% of total phospholipids) and phosphatidylethanolamine (26%) were the predominant phospholipids.
Y Russell, P Evans, G H Dodd
doaj +1 more source
PLoS ONE, 2020 Interaction of phospholipase D2 (PLD2) with phosphatidylinositol (4,5)-bisphosphate (PIP2) is regarded as the critical step of numerous physiological processes.
Kyungreem Han +2 more
doaj +1 more source
Lipidomic analysis of immune activation in equine leptospirosis and Leptospira-vaccinated horses. [PDF]
PLoS ONE, 2018 Currently available diagnostic assays for leptospirosis cannot differentiate vaccine from infection serum antibody. Several leptospiral proteins that are upregulated during infection have been described, but their utility as a diagnostic marker is still ...
Paul L Wood +5 more
doaj +1 more source