Results 81 to 90 of about 5,016,109 (334)

Cancer therapy‐related cardiotoxicity is associated with distinct alterations of the myocardial lipidome

European Journal of Heart Failure, EarlyView.
Lipidome changes in anthracycline‐induced cardiotoxicity (AIC). Aims Anthracyclines are key components of various chemotherapy regimens, but their clinical utility is limited by severe cardiotoxic side effects. Previous studies have suggested that anthracycline‐induced cardiotoxicity (AIC) may be driven by alterations in myocardial lipid metabolism ...
Vera M. Braun, Anna Foryst‐Ludwig, Ulf Landmesser, István Baczkó, Hendrik Milting, Ulrich Kintscher, Niklas Beyhoff   +6 more
wiley   +1 more source

Apparent convergence (at 2-monoacylglycerol level) of phosphatidic acid and 2-monoacylglycerol pathways of synthesis of chylomicron triacylglycerols.

Journal of Lipid Research, 1991
Dietary fats are converted into chylomicron triacylglycerols via the 2-monoacylglycerol and phosphatidic acid pathways of acylglycerol formation. In view of the known positional and fatty acid specificity of the acyltransferases, the triacylglycerol ...
LY Yang, A Kuksis
doaj  

LIPIDS IN REGULATED EXOCYTOSIS: WHAT ARE THEY DOING?

Frontiers in Endocrinology, 2013
TThe regulated secretory pathway in neuroendocrine cells ends with the release of hormones and neurotransmitters following a rise in cytosolic calcium. This process known as regulated exocytosis involves the assembly of soluble N-ethylmaleimide-sensitive
Mohamed Raafet Ammar, Nawal eKassas, Sylvette eChasserot-Golaz, Marie-France eBader, Nicolas eVitale   +4 more
doaj   +1 more source

PLD2-PI(4,5)P2 interactions in fluid phase membranes: Structural modeling and molecular dynamics simulations.

PLoS ONE, 2020
Interaction of phospholipase D2 (PLD2) with phosphatidylinositol (4,5)-bisphosphate (PIP2) is regarded as the critical step of numerous physiological processes.
Kyungreem Han, Richard W Pastor, Cristina Fenollar-Ferrer   +2 more
doaj   +1 more source

Revealing Further Insights on Chilling Injury of Postharvest Bananas by Untargeted Lipidomics

Foods, 2020
Chilling injury is especially prominent in postharvest bananas stored at low temperature below 13 °C. To elucidate better the relationship between cell membrane lipids and chilling injury, an untargeted lipidomics approach using ultra-performance liquid ...
Juan Liu, Qingxin Li, Junjia Chen, Yueming Jiang   +3 more
doaj   +1 more source

A minimal biochemical route towards de novo formation of synthetic phospholipid membranes. [PDF]

, 2019
All living cells consist of membrane compartments, which are mainly composed of phospholipids. Phospholipid synthesis is catalyzed by membrane-bound enzymes, which themselves require pre-existing membranes for function.
Bhattacharya, Ahanjit, Brea, Roberto J, Devaraj, Neal K, Niederholtmeyer, Henrike   +3 more
core   +2 more sources

Myelin Lipid Composition in the Central Nervous System Is Regionally Distinct and Requires Mechanistic Target of Rapamycin Signaling

Glia, EarlyView.
Brain oligodendrocytes have lower rates of cholesterol synthesis and higher rates of lipoprotein uptake than spinal cord oligodendrocytes. Myelin lipid content is higher in CNS regions with larger average axon diameter. Brain and spinal cord myelin cholesterol content is innately different, while myelin fatty acid content can be modulated by fiber ...
Marie L. Mather, Angelina V. Evangelou, Jennifer N. Bourne, Wendy B. Macklin, Teresa L. Wood   +4 more
wiley   +1 more source

Hydrolysis of long-chain alkyl phosphates and phosphatidic acid by an enzyme purified from pig brain*†

Journal of Lipid Research, 1962
Particulate preparations of rat and pig tissues have been found to catalyze the hydrolysis of lipid phosphates including many alcohol dihydrogen phosphates as well as phosphatidic acids.
Bernard W. Agranoff
doaj  

Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.

Circulation Research, 1994
The signaling pathways involved in the long-term metabolic effects of angiotensin II (Ang II) in vascular smooth muscle cells are incompletely understood but include the generation of molecules likely to affect oxidase activity.
K. Griendling, C. Minieri, J D Ollerenshaw, R. Alexander   +3 more
semanticscholar   +1 more source

The Changes in the Lipid Composition of Mung Bean Seeds as Affected by Processing Methods [PDF]

, 2007
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence
Abdel-Rahman, El-Sayed Ali, El-Fishawy, Fawzy A., El-Geddawy, Mohamed A., El-Rify, Mohamed N., Kurz, Tomas   +4 more
core   +1 more source