Results 91 to 100 of about 85,459 (335)

Cancer therapy‐related cardiotoxicity is associated with distinct alterations of the myocardial lipidome

European Journal of Heart Failure, EarlyView.
Lipidome changes in anthracycline‐induced cardiotoxicity (AIC). Aims Anthracyclines are key components of various chemotherapy regimens, but their clinical utility is limited by severe cardiotoxic side effects. Previous studies have suggested that anthracycline‐induced cardiotoxicity (AIC) may be driven by alterations in myocardial lipid metabolism ...
Vera M. Braun, Anna Foryst‐Ludwig, Ulf Landmesser, István Baczkó, Hendrik Milting, Ulrich Kintscher, Niklas Beyhoff   +6 more
wiley   +1 more source

Proposal of \u3cem\u3eVibrionimonas magnilacihabitans\u3c/em\u3e gen. nov., sp. nov., a Curved Gram Negative Bacterium Isolated From Lake Michigan Water [PDF]

, 2014
A mesophilic bacterium appearing as curved rod-shaped cells was isolated from Lake Michigan water. It exhibited highest similarities with Sediminibacterium ginsengisoli DCY13T (94.4 %); Sediminibacterium salmoneum NJ-44T (93.6 %) and Hydrotalea flava ...
Albert, Richard A., Busse, Hans-Jürgen, Dollhopf, Michael, King, Michael, Langer, Stefan, Schauer-Gimenez, Anne, Son, Sona, Struble, Craig, Zitomer, Daniel   +8 more
core   +1 more source

Multi‐Omics Analysis Reveals the Selenium‐Regulatory Metabolism in Rare Yeast Kazachstania unispora KU2

Food Frontiers, EarlyView.
The mechanism of selenium‐regulatory unique metabolism in rare yeast Kazachstania unispora KU2 was explored via joint analysis of genomics, transcriptomics, and metabolomics. Arginine biosynthesis, glutathione metabolism, selenocompound metabolism, and TCA cycle were significantly associated with the selenium enrichment process in Kazachstania unispora
Furong Wang, Jiadi Zhang, Yilei Xiao, Zeyu Hu, Xian Wang, Yuqi Gao, Kewei Feng, Yahong Yuan, Tianli Yue   +8 more
wiley   +1 more source

Aminophospholipid glycation and its inhibitor screening system: a new role of pyridoxal 5′-phosphate as the inhibitor

Journal of Lipid Research, 2006
Peroxidized phospholipid-mediated cytotoxity is involved in the pathophysiology of a number of diseases [i.e., the abnormal increase of phosphatidylcholine hydroperoxide (PCOOH) found in the plasma of type 2 diabetic patients]. The PCOOH accumulation may
Ohki Higuchi, Kiyotaka Nakagawa, Tsuyoshi Tsuzuki, Toshihide Suzuki, Shinichi Oikawa, Teruo Miyazawa   +5 more
doaj  

In Vitro Antithrombotic Properties of Salmon (Salmo salar) Phospholipids in a Novel Food-Grade Extract

Marine Drugs, 2019
Marine and salmon polar lipids (PLs) extracted by conventional extractions with non-food-grade solvents (CE-salmon-PLs) possess antithrombotic bioactivities against platelet-activating factor (PAF) and thrombin.
Alexandros Tsoupras, Ronan Lordan, Katie Shiels, Sushanta Kumar Saha, Constantina Nasopoulou, Ioannis Zabetakis   +5 more
doaj   +1 more source

Thermotomaculum hydrothermale gen. nov., sp. nov., a novel heterotrophic thermophile within the phylum Acidobacteria from a deep-sea hydrothermal vent chimney in the Southern Okinawa Trough [PDF]

, 2012
http://www.godac.jamstec.go.jp/darwin/cruise/natsushima/nt08-13/
A-L Reysenbach, CM Santelli, DA Bryant, DB Meisinger, DE Minnikin, DJ Lane, DL Swofford, H Imachi, H Kampe, Hiroshi Izumi, IH Koch, IS Kulichevskaya, J Sambrook, J Tamaoka, J Tamaoka, J Zimmermann, JA Baross, JD Coates, K Komagata, K Takai, Ken Takai, KG Porter, M Sait, Masayuki Miyazaki, MB Stott, N Kishimoto, N Saitou, NL Ward, P Hugenholtz, P López-García, S Kleinsteuber, S Nakagawa, S Nakagawa, S Nakagawa, S Nakagawa, SA Eichorst, Satoshi Nakagawa, Sayaka Mino, SF Altschul, SM Barns, SM Barns, SM Sievert, T Nunoura, T Nunoura, T Nunoura, TA Pankratov, Takuro Nunoura, TH Jukes, Tomohiro Toki, Tomoo Sawabe, W Liesack, W Ludwig, W Ludwig, W Zillig, WJ Brazelton, Y Fukunaga, Y Sako, Yoshihiko Sako   +57 more
core   +1 more source

Myelin Lipid Composition in the Central Nervous System Is Regionally Distinct and Requires Mechanistic Target of Rapamycin Signaling

Glia, EarlyView.
Brain oligodendrocytes have lower rates of cholesterol synthesis and higher rates of lipoprotein uptake than spinal cord oligodendrocytes. Myelin lipid content is higher in CNS regions with larger average axon diameter. Brain and spinal cord myelin cholesterol content is innately different, while myelin fatty acid content can be modulated by fiber ...
Marie L. Mather, Angelina V. Evangelou, Jennifer N. Bourne, Wendy B. Macklin, Teresa L. Wood   +4 more
wiley   +1 more source

Use of the isolated perfused rat lung in studies on lung lipid metabolism

Journal of Lipid Research, 1973
A procedure for the use of the isolated perfused rat lung in studies on metabolic regulation has been developed. The procedure, reasonably uncomplicated, yet physiological, maintains the lung so that edema is not observed.
Rodolfo I. Godinez, William J. Longmore
doaj  

Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP [PDF]

, 1999
Raf-1 phosphorylates and activates MEK-1, a kinase that activates the extracellular signal regulated kinases (ERK). This kinase cascade controls the proliferation and differentiation of different cell types.
A Minden, A Sewing, AD Catling, B Hallberg, CJ Marshall, D Woods, DK Grandy, DK Morrison, DW Rose, F Schoentgen, Ferrell, J. E. Jr, Ferrell, J. E. Jr, H Mischak, HJ Schaeffer, JT Bruder, KL Guan, M Kortenjann, OV Gjorup, RM Lavbinsky, RM Tombes, S Häfner, S Li, SA Moodie, UR Rapp, W Kolch, W Kolch   +25 more
core   +1 more source

A rapid phospholipase D assay using zirconium precipitation of anionic substrate phospholipids: application to N-acylethanolamine formation in vitro

Journal of Lipid Research, 2000
Activation of phospholipase D (PLD) is involved in a number of signal transduction pathways in eukaryotic cells. The most common method for determination of PLD activity in vitro involves incubation with a radiolabeled substrate and lipid extraction ...
Gitte Petersen, Kent D. Chapman, Harald S. Hansen   +2 more
doaj