Results 181 to 190 of about 106,919 (341)

Membrane Topography of Human Phosphatidylethanolamine N-Methyltransferase

, 2003
David J. Shields, Richard Lehner, Luis B. Agellon, Dennis E. Vance   +3 more
openalex   +1 more source

CRISPR/Cas9‐mediated Genome‐editing Reveals 10 Testis‐enriched Genes and One Non‐testis‐enriched Gene are Dispensable for Male Fecundity in Mice

Andrology, EarlyView.
ABSTRACT Background More than 1000 genes have been identified as predominantly expressed in the human testis. Advances in gene editing technologies have enabled the rapid and efficient generation of genetically engineered mice. This approach facilitates the screening of genes essential for spermatogenesis by analyzing knockout mouse models.
Yumiao Qiu, Keisuke Shimada, Masahito Ikawa   +2 more
wiley   +1 more source

Impairment of lymphocyte locomotion in the tumor microenvironment and the effect of systemic immunotherapy with liposome-encapsulated myramyl-tripeptide-phosphatidylethanolamine

, 1995
Diana Risin, Eugenie S. Kleinerman, Yasuiki Umezu, Roland P. Pizzini, Charles M. Balch, Neal R. Pellis   +5 more
openalex   +2 more sources

Upregulation of sphingomyelin and ABCA8 in response to TDP‐43 pathology in amyotrophic lateral sclerosis brain

Brain Pathology, EarlyView.
Increases in sphingomyelin in response to TDP‐43 pathology in the disease‐affected motor cortex of amyotrophic lateral sclerosis (ALS) brain. Abstract Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease characterized by the degeneration of motor neurons and the presence of TAR DNA‐binding protein 43 (TDP‐43 ...
Finula I. Isik, Russell Pickford, Nicolas Dzamko, Kerry‐Anne Rye, Woojin Scott Kim   +4 more
wiley   +1 more source

Phosphatidylserine in Addition to Phosphatidylethanolamine Is an in Vitro Target of the Mammalian Atg8 Modifiers, LC3, GABARAP, and GATE-16 [PDF]

, 2005
Yu‐shin Sou, Isei Tanida, Masaaki Komatsu, Takashi Ueno, Eiki Kominami   +4 more
openalex   +1 more source

Phosphatidylethanolamine

Trends in Endocrinology & Metabolism
Mackenzie T. Primrose, Steven M. Claypool   +1 more
openaire   +2 more sources

Non‐Coding RNAs in Breast Cancer Radioresistance: Mechanisms, Functional Roles and Translational Potentials

Cell Proliferation, EarlyView.
Non‐coding RNAs (ncRNAs) regulate breast cancer radioresistance via cell cycle, DNA repair and tumour microenvironment pathways. Targeting ncRNAs (e.g., HOTAIR and miR‐155) with RNA‐based therapies (ASOs and CRISPR) shows promise but faces delivery challenges.
Xiaohui Zhao, Yuting Qiu, Jie Chen, Danni Wang, Zairui Wang, Shuang Ma, Yimin Liu, Guoying Liu, Zhuofei Bi   +8 more
wiley   +1 more source

Common genetic polymorphisms define one-carbon metabolite responses to different forms of choline in healthy adult males. [PDF]

Front Nutr
Butt N, Dong J, Shelp GV, Poole EM, Keathley JR, Bakovic M, Cho CE.   +6 more
europepmc   +1 more source

Mitophagy and Bip–PERK–eIF2α–ATF4 Axis‐Mediated ER Stress Mediate Miriplatin‐Loaded Liposome's Anti‐Colorectal Cancer Action

Cell Proliferation, EarlyView.
LMPt enters the cell mainly through caveolin‐mediated endocytosis, and then fuses with endosomes and lysosomes to deliver MPt to mitochondria and the endoplasmic reticulum to induce mitophagy based on the fusion of lysosomes and mitochondria, and endoplasmic reticulum stress and subsequent apoptosis via the Bip–PERK–eIF2α–ATF4 axis to exert an anti ...
Cong Zhao, Yuhan Qiu, Xiaowei Wang, Mengyan Wang, Li Liu, Xiaojun Zhao, Zixiang Gao, Rongguang Shao, Guimin Xia, Wuli Zhao   +9 more
wiley   +1 more source

Deep structural lipidomic profiling reveals C=C positional isomers as potential biomarkers in lung adenocarcinoma tissue. [PDF]

Transl Lung Cancer Res
Gu Y, Shao MM, Cui SP, Hu B, Li X.
europepmc   +1 more source