RANKL treatment induces expression of the aconitate decarboxylase (ACOD1) in differentiating osteoclasts, which increases succinate levels. The initially high expression of ACOD1 decreases towards the end of differentiation when the levels of the desuccinylase SIRT5 increase. Succinylation of citrate synthase (CS) was detected exclusively in stimulated
Dayoung Yu+7 more
wiley +1 more source
Causal relationship between plasma lipidome and rosacea: a Mendelian randomization analysis. [PDF]
Wang X, Zhu Z.
europepmc +1 more source
Myelin is a multilayered proteolipid membrane in the nervous system. The lipid membranes are held together by specific proteins, and here, we studied three such proteins—P0, MBP, and P2. Our experiments show that the three proteins may act in synergy at the molecular level, while they also compete for lipid membrane surface binding.
Oda C. Krokengen+9 more
wiley +1 more source
Mendelian randomization analysis reveals potential causal relationships between serum lipid metabolites and prostate cancer risk. [PDF]
Guo C, Wu L, Xu L.
europepmc +1 more source
Short coiled‐coil proteins from plants and metazoans – the ‘jacks of all trades’
Short coiled‐coil proteins from plants and metazoans—true ‘jacks of all trades’—play supporting but crucial roles in cellular stress response, metabolism, autophagy, and membrane dynamics. Despite their small size and modest sequence conservation, proteins like plant LSUs and metazoan SCOCs showcase remarkable functional versatility shaped by evolution,
Agnieszka Sirko+2 more
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Causal relationship between the plasma lipidome and urological cancers: A two-sample Mendelian randomization study. [PDF]
Chen R, He L, Huang Z, Sun J, Wang Q.
europepmc +1 more source
Coronary artery disease risk and lipidomic profiles are similar in hyperlipidemias with family history and population-ascertained hyperlipidemias [PDF]
et al,, Stitziel, Nathan O
core +1 more source
The facial SC lipid profiles of young Chinese women in the early aging stage exhibited significant changes with age. The average chain length of diacylglycerol, triacylglycerol and short‐chain ceramides decreases with age, while the cholesteryl ester and ceramide EO subclasses increase. Some ceramides correlate positively with TEWL, skin elasticity and
Yumei Fan+6 more
wiley +1 more source
Correlation of anti-phosphatidylethanolamine antibodies with premature birth in women with a history of miscarriage: a retrospective study. [PDF]
Pan Y, Bao R, Xiang J, Cai Z.
europepmc +1 more source
Barrier characteristics of membrane model systems containing unsaturated phosphatidylethanolamines [PDF]
P.C. Noordam+4 more
openalex +1 more source