Results 21 to 30 of about 8,868 (194)
Journal of Lipid Research, 2015 Mice that lack phosphatidylethanolamine N-methyltransferase (Pemt−/− mice) are protected from high-fat (HF) diet-induced obesity. HF-fed Pemt−/− mice show higher oxygen consumption and heat production, indicating that more energy might be utilized for ...
Xia Gao +5 more
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Genome-Wide Association Study of Egg-Laying Traits and Egg Quality in LingKun Chickens
Frontiers in Veterinary Science, 2022 Egg production is the most important trait of laying hens. To identify molecular markers and candidate genes associated with egg production and quality, such as body weight at first oviposition (BWF), the number of eggs produced in 500 days (EN500), egg ...
Jinfeng Gao +11 more
doaj +1 more source
Physiological consequences of disruption of mammalian phospholipid biosynthetic genes
Journal of Lipid Research, 2009 By 1959, Eugene Kennedy and coworkers had outlined most pathways of phospholipid biosynthesis. In the next four decades, the emphasis was on enzymology and regulation of these pathways.
Dennis E. Vance, Jean E. Vance
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Insights into the requirement of phosphatidylcholine synthesis for liver function in mice
Journal of Lipid Research, 2003 Phosphatidylcholine (PC) is made in the liver by the CDP-choline pathway and via phosphatidylethanolamine N-methyltransferase (PEMT), which catalyzes the conversion of phosphatidylethanolamine to PC.
Anna A. Noga, Dennis E. Vance
doaj +1 more source
Phosphatidylcholine synthesis through cholinephosphate cytidylyltransferase is dispensable in Leishmania major [PDF]
, 2019 © 2019, The Author(s). cc-byPhosphatidylcholine (PC) is a major cell membrane constituent and precursor of important second messengers. In Leishmania parasites, PC synthesis can occur via the choline branch of the Kennedy pathway, the N-methylation of ...
Hsu, Fong-Fu +3 more
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Diminished expression of phosphatidylethanolamine N-methyltransferase 2 during hepatocarcinogenesis [PDF]
Biochemical Journal, 1998 Phosphatidylethanolamine N-methyltransferase (PEMT) is a liver-specific enzyme that converts phosphatidylethanolamine into phosphatidylcholine. At least two forms of PEMT are present in hepatocytes. However, PEMT activity is negligible in two hepatoma cell lines. Previous studies have indicated an inverse relationship between the expression of one form,
TESSITORE, Luciana +3 more
openaire +3 more sources
Phosphatidylethanolamine Levels and Regulation of Phosphatidylethanolamine N- Methyltransferase
Journal of Biological Chemistry, 1989 The activity of phosphatidylethanolamine (PE) N-methyltransferase in liver microsomes, measured using endogenous microsomal PE as a substrate, was elevated 2-fold in the choline-deficient state. However, methyltransferase activity assayed in the presence of a saturating concentration of phosphatidyl-N-mono-methylethanolamine or microsomal PE was ...
N D, Ridgway, Z, Yao, D E, Vance
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Wide-targeted gene expression infers tissue-specific molecular signatures of lipid metabolism in fed and fasted fish [PDF]
, 2017 European sea bass (Dicentrarchus labrax) is one of the most important species for Mediterranean aquaculture. It is therefore crucial to establish appropriate feeding management regimens and to gain better knowledge of nutritional requirements for this ...
Benedito-Palos, Laura +3 more
core +1 more source
Hepatic Phosphatidylethanolamine N-Methyltransferase Expression Is Increased in Diabetic Rats [PDF]
The Journal of Nutrition, 2006 Phosphatidylcholine is an essential phospholipid that is synthesized by 2 different pathways, the CDP-choline pathway and the methylation of phosphatidylethanolamine by phosphatidylethanolamine N-methyltransferase (PEMT). Recent studies have suggested that PEMT is an important consumer of methyl groups from S-adenosylmethionine (SAM) and is a major ...
Cara S, Hartz +4 more
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Journal of Lipid Research, 2007 The phosphatidylethanolamine N-methyltransferase (PEMT) pathway of phosphatidylcholine (PC) biosynthesis is not essential for the highly specific acyl chain composition of biliary PC.
Henkjan J. Verkade +7 more
doaj +1 more source