Results 31 to 40 of about 8,868 (194)
Redox Biology, 2021 Mitochondrial energy production and function rely on optimal concentrations of the essential redox-active lipid, coenzyme Q (CoQ). CoQ deficiency results in mitochondrial dysfunction associated with increased mitochondrial oxidative stress and a range of
Anita Ayer +19 more
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Role of Nutrition in Alcoholic Liver Disease: Summary of the Symposium at the ESBRA 2017 Congress. [PDF]
, 2018 The symposium, "Role of Nutrition in Alcoholic Liver Disease", was held at the European Society for Biomedical Research on Alcoholism Congress on 9 October 2017 in Crete, Greece. The goal of the symposium was to highlight recent advances and developments
Feldstein, Ariel E +8 more
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Localization-independent Regulation of Homocysteine Secretion by Phosphatidylethanolamine N-Methyltransferase [PDF]
Journal of Biological Chemistry, 2005 Genetic ablation of phosphatidylethanolamine N-methyltransferase (PEMT) in mice causes a 50% reduction in plasma homocysteine (Hcy) levels. Because hyperhomocysteinemia is an independent risk factor for cardiovascular disease, resolution of the molecular basis for this reduction is of significant clinical interest.
David J, Shields +4 more
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Does litomosoides sigmodontis synthesize dimethylethanolamine from choline? [PDF]
, 2008 Juvenile female Litomosoides sigmodontis secrete a protein (Juv-p120) highly modified with dimethylethanolamine (DMAE). In an attempt to establish the source of this decoration worms were pulsed with [3H]-choline and [3H]-ethanolamine and the radio ...
Allen, J E +4 more
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Rodent and nonrodent malaria parasites differ in their phospholipid metabolic pathways[S]
Journal of Lipid Research, 2010 Malaria, a disease affecting humans and other animals, is caused by a protist of the genus Plasmodium. At the intraerythrocytic stage, the parasite synthesizes a high amount of phospholipids through a bewildering number of pathways.
Sandrine Déchamps +5 more
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Frontiers in Immunology, 2020 FcgRIIB dysfunction is commonly found in patients with lupus, especially in Asia. LPS-tolerance is prominent in FcgRIIB–/– lupus mice. LPS-tolerant macrophages demonstrate cell energy depletion, which might affect lipid metabolism.
Thiranut Jaroonwitchawan +6 more
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Atorvastatin Provides a New Lipidome Improving Early Regeneration After Partial Hepatectomy in Osteopontin Deficient Mice [PDF]
, 2018 Osteopontin (OPN), a multifunctional cytokine that controls liver glycerolipid metabolism, is involved in activation and proliferation of several liver cell types during regeneration, a condition of high metabolic demands.
Aspichueta Celaá, Patricia +10 more
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Journal of Lipid Research, 2018 Acute respiratory distress syndrome (ARDS) is associated with a severe pro-inflammatory response; although decreased plasma cholesterol concentration has been linked to systemic inflammation, any association of phospholipid metabolic pathways with ARDS ...
Ahilanandan Dushianthan +3 more
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High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice. [PDF]
, 2015 Increased consumption of folic acid is prevalent, leading to concerns about negative consequences. The effects of folic acid on the liver, the primary organ for folate metabolism, are largely unknown.
Best, A +10 more
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Lipids in Health and Disease, 2017 Background Acetaminophen (APAP) overdose is one of the most common causes of acute liver failure in many countries. The aim of the study was to describe the profiling of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) in the plasma and liver ...
Ya-Nan Ming +8 more
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