Results 181 to 190 of about 405,250 (376)

Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review

Food Frontiers, EarlyView.
Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv, Yuanyuan Huang, Mokhtar Dabbour, Benjamin Kumah Mintah, Ronghai He, Haile Ma   +5 more
wiley   +1 more source

8-Nitrotryptanthrin inhibits colorectal cancer progression via TGF-β/SMAD and PI3K/AKT/mTOR pathways

Frontiers in Pharmacology
ObjectiveTo investigate the anticancer effects and underlying mechanisms of 8-nitrotryptanthrin (8-Nitrotryp) against colorectal cancer (CRC).MethodsThe effects of 8-Nitrotryp on proliferation, colony formation, and migration were evaluated in HCT116 and
Cheng-Yu Sun, Kai-Ping Cong, Kai-Ping Cong, Dan-Dan Zhao, En-Guo Fan, Ming-Quan Guo, Ming-Quan Guo, Zheng-Guo Zhang   +7 more
doaj   +1 more source

Salidroside Suppresses IL-1β-Induced Apoptosis in Chondrocytes via Phosphatidylinositol 3-Kinases (PI3K)/Akt Signaling Inhibition. [PDF]

Med Sci Monit, 2019
Wu M, Hu R, Wang J, An Y, Lu L, Long C, Yan L.   +6 more
europepmc   +1 more source

Phosphatidylinositol 3-Kinase Activity Is Important for Progesterone-Induced Xenopus Oocyte Maturation

, 1993
Anthony J. Muslin, Anke Klippel, Lewis T. Williams   +2 more
openalex   +2 more sources

Phloretin Suppresses Bone Morphogenetic Protein-2-Induced Osteoblastogenesis and Mineralization via Inhibition of Phosphatidylinositol 3-kinases/Akt Pathway. [PDF]

Int J Mol Sci, 2019
Takeno A, Kanazawa I, Tanaka KI, Notsu M, Sugimoto T.   +4 more
europepmc   +1 more source

Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling

, 2005
Yufeng Yang, Stephan Gehrke, Md. Emdadul Haque, Yuzuru Imai, Jon C. Kosek, Lichuan Yang, M. Flint Beal, Isao Nishimura, Kazumasa Wakamatsu, Shosuke Ito, Ryōsuke Takahashi, Bingwei Lu   +11 more
openalex   +2 more sources

Membrane rafts in T cell activation: A spotlight on CD28 costimulation [PDF]

, 2017
Abrahamsen, Acuto, Ambach, Asanov, August, Bi, Billadeau, Bjørgo, Byrum, Chiang, Chuang, Comrie, Davis, Dennehy, Dupré, Dustin, Eggeling, Esensten, Fischer, Garçon, Gaus, Golub, Gri, Harada, Harder, Harding, Hayashi, Head, Holdorf, Hui, June, Kabouridis, Kallikourdis, Kamphorst, Kenworthy, Kim, Kong, Krawczyk, Kündig, Lasserre, Ledbetter, Lee, Liang, Lichtenberg, Lingwood, Liu, Marengère, Martin, Mayor, Monks, Muscolini, Muscolini, Muscolini, Nakamura, Owen, Paccani, Pagès, Pike, Pike, Pike, Pizzo, Porciello, Porciello, Pralle, Raab, Raab, Raychaudhuri, Resh, Roncagalli, Round, Ruppelt, Russell, Salazar-Fontana, Salomon, Sanchez-Lockhart, Schütz, Shahinian, Sherman, Simons, Simons, Subczynski, Tavano, Tavano, Varma, Varshney, Villalba, Villalba, Viola, Viola, Viola, Viola, von Haller, Watanabe, Yokosuka, Zhang, Zhang   +95 more
core   +1 more source

Formiminotransferase Cyclodeaminase Suppresses Hepatocellular Carcinoma by Modulating Cell Apoptosis, DNA Damage, and Phosphatidylinositol 3-Kinases (PI3K)/Akt Signaling Pathway. [PDF]

Med Sci Monit, 2019
Chen J, Chen Z, Huang Z, Yu H, Li Y, Huang W.   +5 more
europepmc   +1 more source

Phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase regulate induction of Mcl-1 and survival in glucocorticoid-treated human neutrophils [PDF]

, 2007
Arash S. Saffar, Stéphane Dragon, Peyman Ezzati, Lianyu Shan, Abdelilah S. Gounni   +4 more
openalex   +1 more source

Genomic and proteomic profiling of responses to toxic metals in human lung cells. [PDF]

, 2003
Examining global effects of toxic metals on gene expression can be useful for elucidating patterns of biological response, discovering underlying mechanisms of toxicity, and identifying candidate metal-specific genetic markers of exposure and response ...
Andrew, Angeline S, Barchowsky, Aaron, Hamilton, Joshua W, Klei, Linda, O'Hara, Kimberley A, Soucy, Nicole V, Temple, Kaili A, Warren, Amy J   +7 more
core   +2 more sources