Results 191 to 200 of about 77,486 (386)
Serotonergic Modulators in Alzheimer's Disease: A Hope in the Hopeless Condition
Chemistry &Biodiversity, EarlyView.ABSTRACT Alzheimer's disease (AD) is the main cause of dementia worldwide. AD is a progressive brain neurodegenerative disease due to genetic and environmental factors that induce a progressive accumulation of intracellular hyperphosphorylated tau protein and extracellular amyloid protein (Aβ).
Najlaa Hamed Almohmadi +7 more
wiley +1 more source
Enrichment of phosphatidylinositols with specific acyl chains.
Biochimica et Biophysica Acta, 2014 Kenneth D'souza, R. Epand
semanticscholar +1 more source
ChemBioChem, Accepted Article.Upon cell stimulation, mammalian cells activate various signaling proteins and lipids by recruiting their upstream regulators to the inner leaflet of the plasma membrane (PM), which in turn determines their cellular response. Therefore, artificially inducing protein translocation to the PM is an effective strategy for dissecting cell signaling networks
Shuya Ohira +3 more
wiley +1 more source
Differential regulation by phosphatidylinositol 4,5-bisphosphate of pituitary plasma-membrane and cytosolic phosphoinositide kinases [PDF]
, 1986 Akihiro Imai +2 more
openalex +1 more source
Disruption of Retriever Function Impacts Retrograde Trafficking From Endosomes
Cell Biology International, EarlyView.ABSTRACT Within endosomes cargo proteins are sorted and packaged into endosomal‐transport carriers (ETCs) enabling their delivery to other intracellular compartments. Retromer, a conserved multimeric protein complex, has defined functions in sorting cargo mediating formation of ETCs for both retrograde trafficking back to the trans‐Golgi network (TGN ...
Zebin Li, Zhe Yang, Rohan D. Teasdale
wiley +1 more source
Enhanced metabolism of phosphatidylinositol in Candida tropicalis in association with filamentous growth caused by ethanol [PDF]
, 1987 Yasuhide Uejima +2 more
openalex +1 more source
Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly
Cytoskeleton, EarlyView.ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley +1 more source
Journal of Lipid Research, 2018 Understanding FA metabolism and lipid synthesis requires a lot of information about which FAs and lipids are formed within the cells. We focused on the use of deuterated substrates of 100 μM α-linolenic acid and linoleic acid to determine the relative ...
Mai H. Philipsen +3 more
doaj
British Journal of Pharmacology, 2012 Jian Shi, M. Ju, W. Large, A. Albert
semanticscholar +1 more source