Results 51 to 60 of about 77,486 (386)
Recognizing Phosphatidylinositol 3-Phosphate [PDF]
Cell, 2001 Phosphatidylinositol 3-phosphate directs the endosomal localization of regulatory proteins by binding to FYVE and PX domains. New structures of these domains complexed with the phosphoinositide headgroup show how interactions with phosphate and hydroxyl groups differentiate this lipid from all others.
James H. Hurley +2 more
openaire +3 more sources
Fatty acid stimulation of membrane phosphatidylinositol hydrolysis by brain phosphatidylinositol phosphodiesterase [PDF]
Biochemical Journal, 1979 The hydrolysis of membrane-bound phosphatidylinositol in rat liver microsomal fraction by the soluble phosphatidylinositol phosphodiesterase from rat brain was markedly stimulated by oleic acid or arachidonic acid. The stimulation did not require added calcium, although it was abolished by EDTA.
A J Letcher +2 more
openaire +3 more sources
Phosphatidylinositol synthesis at the endoplasmic reticulum [PDF]
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2020 Phosphatidylinositol (PI) is a minor phospholipid with a characteristic fatty acid profile; it is highly enriched in stearic acid at the sn-1 position and arachidonic acid at the sn-2 position. PI is phosphorylated into seven specific derivatives, and individual species are involved in a vast array of cellular functions including signalling, membrane ...
Blunsom, NJ, Cockcroft, S
openaire +4 more sources
Biomédica: revista del Instituto Nacional de Salud, 2015 Introducción. La leishmaniasis es una enfermedad de gran impacto en la salud pública. La Organización Mundial de la Salud considera prioritaria la investigación orientada al desarrollo de medicamentos para su tratamiento.
Valeria Velásquez +2 more
doaj +1 more source
EHD1 and Eps15 Interact with Phosphatidylinositols via Their Eps15 Homology Domains*
Journal of Biological Chemistry, 2007 The C-terminal Eps15 homology domain-containing protein, EHD1, regulates the recycling of receptors from the endocytic recycling compartment to the plasma membrane. In cells, EHD1 localizes to tubular and spherical recycling endosomes.
Naava Naslavsky +4 more
semanticscholar +1 more source
Effects of 3D Geometries on Cellular Gradient Sensing and Polarization
, 2016 During cell migration, cells become polarized, change their shape, and move in response to various internal and external cues. Cell polarization is defined through the spatio-temporal organization of molecules such as PI3K or small GTPases, and is ...
Andasari, Vivi +4 more
core +1 more source
Glycophosphosphingolipid (GSPL) Purification Protocol
Bio-Protocol, 2012 Glycosylated ceramide phosphorylinositol are present in many species of fungi and mushrooms and bacteria and parasitic organisms like leishmania. These are usually membrane raft associated and are not easily extracted by conventional methodologies.
Tripti De
doaj +1 more source
Physiological Reports, 2022 Infants with neonatal cholestasis are prone to neurodevelopmental deficits, however, the underlying pathogenesis is unclear. Lipid malabsorption and accumulation of potentially neurotoxic molecules in the blood such as bile acids are important yet ...
Nicole Lind Henriksen +12 more
doaj +1 more source
Electrodiffusion of Lipids on Membrane Surfaces [PDF]
, 2011 Random lateral translocation of lipids and proteins is a universal process on membrane surfaces. Local aggregation or organization of lipids and proteins can be induced when this lateral random diffusion is mediated by the electrostatic interactions and membrane curvature. Though the lateral diffusion rates of lipids on membrane of various compositions
arxiv +1 more source
Lipidomic profiling in Crohn's disease: abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition. [PDF]
, 2012 Crohn's disease is a chronic inflammatory condition largely affecting the terminal ileum and large bowel. A contributing cause is the failure of an adequate acute inflammatory response as a result of impaired secretion of pro-inflammatory cytokines by ...
Bielawski, J +12 more
core +1 more source