Results 61 to 70 of about 8,270 (191)

Toxoplasma gondii major surface antigen (SAG1): in vitro analysis of host cell binding [PDF]

, 2004
Previous studies have indicated that SAG1, the major surface molecule of the protozoan parasite Toxoplasma gondii, is an important attachment ligand for the host cell.
Millner, P.A., Robinson, S.A., Smith, J.E.   +2 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Plasma membrane lipid remodeling during cold acclimation is mediated by the ER-PM contact sites-localized synaptotagmins 1 and 3 [PDF]

, 2016
Cold acclimation is the capacity of certain plants to increase their freezing tolerance in response to a period of low non-freezing temperatures.
Botella-Mesa, Miguel Angel, Osorio-Algar, Sonia, Pérez-Sancho, Jessica, Rosado, Abel, Ruiz-Lopez, Noemi, Salinas, Julio, Schapire, Arnaldo, Vanneste, Steffen, Willtmitzer, Lothar   +8 more
core  

The MBOAT7 variant rs641738 alters hepatic phosphatidylinositols and increases severity of non-alcoholic fatty liver disease in humans [PDF]

, 2016
Non peer ...
Arola, Johanna, Hyotylainen, Tuulia, Leivonen , Marja, Luukkonen, Panu K., Oresic, Matej, Orho-Melander, Marju, Yki-Jarvinen, Hannele, Zhou, You   +7 more
core   +1 more source

Integration Profiling Between Plasma Lipidomics, Epstein–Barr Virus and Clinical Phenomes in Nasopharyngeal Carcinoma Patients

Frontiers in Microbiology, 2022
Plasma lipidomics has been commonly used for biomarker discovery. Studies in cancer have suggested a significant alteration of circulating metabolite profiles which is correlated with cancer characteristics and treatment outcome.
Yi Huang, Jinfeng Liang, Wenjin Hu, Yushan Liang, Xue Xiao, Weilin Zhao, Xuemin Zhong, Xuemin Zhong, Yanping Yang, Yanping Yang, Xinli Pan, Xiaoying Zhou, Zhe Zhang, Zhe Zhang, Yonglin Cai   +14 more
doaj   +1 more source

Crosstalk Between Brain-Derived Neurotrophic Factor And N-Methyl-D-Aspartate Receptor Signaling In Neurons [PDF]

, 2008
Glutamate is the major excitatory neurotransmitter in brain exerting prosurvival effect on neurons via N-methyl-D-aspartate receptor (NMDAR) signaling under physiological conditions.
Georgiev, Danko, Kambe, Yuki, Taniura, Hideo, Yoneda, Yukio   +3 more
core  

Evolutionary history of phosphatidylinositol- 3-kinases: ancestral origin in eukaryotes and complex duplication patterns [PDF]

, 2015
BACKGROUND: Phosphatidylinositol-3-kinases (PI3Ks) are a family of eukaryotic enzymes modifying phosphoinositides in phosphatidylinositols-3-phosphate.
Céline Brochier-Armanet, Guy Perrière, Héloïse Philippon   +2 more
core   +1 more source

Differentiating human phospholipase A2's activity toward phosphatidylinositol, phosphatidylinositol phosphate and phosphatidylinositol bisphosphate

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Phospholipase A2's (PLA2's) constitute a superfamily of enzymes that hydrolyze the sn-2 fatty acyl chain on glycerophospholipids. We have previously reported that each PLA2 Type shows a unique substrate specificity for the molecular species it hydrolyzes, especially the acyl chain that is cleaved from the sn-2 position and to some extent the polar ...
Hayashi, Daiki, Dennis, Edward A.
openaire   +3 more sources

Mass spectrometry–based lipidomics of oral squamous cell carcinoma tissue reveals aberrant cholesterol and glycerophospholipid metabolism — A Pilot study

Translational Oncology, 2020
Lipid metabolic reprogramming is one hallmark of cancer. Lipid metabolism is regulated by numerous enzymes, many of which are targeted by several drugs on the market.
Amy Dickinson, Mayank Saraswat, Sakari Joenväärä, Rahul Agarwal, Daniel Jyllikoski, Tommy Wilkman, Antti Mäkitie, Suvi Silén   +7 more
doaj   +1 more source

Differences in levels of phosphatidylinositols in healthy and stable Coronary Artery Disease subjects revealed by HILIC-MRM method with SERRF normalization.

PLoS ONE, 2021
Quantification of endogenous biomarkers in clinical studies requires careful evaluation of a number of assay performance parameters. Comparisons of absolute values from several clinical studies can enable retrospective analyses further elucidating the ...
Yue Huang, Ruipeng Mu, David Wen, Joseph S Grimsby, Meina Liang, Anton I Rosenbaum   +5 more
doaj   +1 more source