Results 21 to 30 of about 108,878 (236)

Hemagglutinating activity of phosphatidylserine [PDF]

open access: yesFEBS Letters, 1983
In [l] we reported the structure and hemagglutinating activity of an ornithine-containing lipid of Bordetella pertussis. The proposed structure of the aminolipid is 3-hydroxyhexadecanoic acid amide-linked to ornithine and esterified to the second hexadecanoic acid. The aminolipid strongly agglutinated human and rabbit erythrocytes. Here, I describe the
openaire   +3 more sources

First-in-man evaluation of 124I-PGN650: A PET tracer for detecting phosphatidylserine as a biomarker of the solid tumor microenvironment [PDF]

open access: yes, 2017
Purpose: PGN650 is a F(ab′) 2 antibody fragment that targets phosphatidylserine (PS), a marker normally absent that becomes exposed on tumor cells and tumor vasculature in response to oxidative stress and increases in response to therapy.
Dehdashti, Farrokh   +9 more
core   +2 more sources

Role of Calcium in Phosphatidylserine Externalisation in Red Blood Cells from Sickle Cell Patients

open access: yesAnemia, 2011
Phosphatidylserine exposure occurs in red blood cells (RBCs) from sickle cell disease (SCD) patients and is increased by deoxygenation. The mechanisms responsible remain unclear.
Erwin Weiss   +2 more
doaj   +1 more source

Stabilin Receptors: Role as Phosphatidylserine Receptors

open access: yesBiomolecules, 2019
Phosphatidylserine is a membrane phospholipid that is localized to the inner leaflet of the plasma membrane. Phosphatidylserine externalization to the outer leaflet of the plasma membrane is an important signal for various physiological processes ...
Seung-Yoon Park, In-San Kim
doaj   +1 more source

Osh6 Revisited: Control of PS Transport by the Concerted Actions of PI4P and Sac1 Phosphatase

open access: yesFrontiers in Molecular Biosciences, 2021
Osh6, a member of the oxysterol-binding protein–related protein (ORP) family, is a lipid transport protein that is involved in the transport of phosphatidylserine (PS) between the endoplasmic reticulum (ER) and the plasma membrane (PM).
Andrea Eisenreichova   +3 more
doaj   +1 more source

Transport of Phosphatidylserine from the Endoplasmic Reticulum to the Site of Phosphatidylserine Decarboxylase2 in Yeast [PDF]

open access: yesTraffic, 2014
Over the past two decades, most of the genes specifying lipid synthesis and metabolism in yeast have been identified and characterized. Several of these biosynthetic genes and their encoded enzymes have provided valuable tools for the genetic and biochemical dissection of interorganelle lipid transport processes in yeast.
Wayne R. Riekhof   +2 more
openaire   +3 more sources

The effect of addition protein, phosphatidylcholine, phosphatidylserine, and inulin on GFAP levels of acute ischemic stroke patients at Dr. Kariadi Hospital, Semarang

open access: yesJurnal Gizi Indonesia: The Indonesian Journal of Nutrition, 2021
Background: The occurrence of ischemia causes a loss of energy to switch to anaerobic processes resulting in acidosis due to reduced Adenosina Triphosphate (ATP). This condition makes neuron cells apoptotic. Apoptotic of several biochemical substrates in
Diah Retno Wahyuningrum   +2 more
doaj   +1 more source

Nanoelectropulse-Induced Phosphatidylserine Translocation [PDF]

open access: yesBiophysical Journal, 2004
Nanosecond, megavolt-per-meter, pulsed electric fields induce phosphatidylserine (PS) externalization, intracellular calcium redistribution, and apoptosis in Jurkat T-lymphoblasts, without causing immediately apparent physical damage to the cells. Intracellular calcium mobilization occurs within milliseconds of pulse exposure, and membrane phospholipid
Martin A. Gundersen   +5 more
openaire   +2 more sources

Loss of maternal annexin A5 increases the likelihood of placental platelet thrombosis and foetal loss [PDF]

open access: yes, 2012
Antiphospholipid syndrome is associated with an increased risk of thrombosis and pregnancy loss. Annexin A5 (Anxa5) is a candidate autoantigen. It is not known, however, whether endogenous Anxa5 prevents foetal loss during normal pregnancy.
Brachvogel, Bent   +11 more
core   +1 more source

Regulation of Anti-Phosphatidylserine Antibodies [PDF]

open access: yesImmunity, 2003
The degree of heavy chain (H) editing, the types of Vkappa editors, and the pattern of Jkappa usage are correlated with a range of the affinity of anti-DNA. This range was determined by the number and location of arginine (R) residues in the VH. We, here, changed a key arginine residue in the VH of anti-DNA transgene to glycine, which sharply reduces ...
Marko Z. Radic   +5 more
openaire   +3 more sources

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