Results 11 to 20 of about 8,775 (288)

Plasma procoagulant phospholipid clotting time and venous thromboembolism risk

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2021
Background Negatively charged procoagulant phospholipids, phosphatidylserine (PS) in particular, are vital to coagulation and expressed on the surface membrane of extracellular vesicles.
Cathrine Ramberg   +7 more
doaj   +1 more source

Fumonisin B Series Mycotoxins’ Dose Dependent Effects on the Porcine Hepatic and Pulmonary Phospholipidome

open access: yesToxins, 2022
Male weaned piglets n = 6/group were fed Fumonisin B1+2+3 (FBs) mycotoxins at 0, 15, or 30 mg/kg diet for 3 weeks to assess the fatty acid (FA) composition of membrane lipid classes, lipid peroxidation, and histomorphological changes in the liver and ...
Omeralfaroug Ali   +5 more
doaj   +1 more source

Worms, Fat, and Death: Caenorhabditis elegans Lipid Metabolites Regulate Cell Death

open access: yesMetabolites, 2021
Caenorhabditis elegans is well-known as the model organism used to elucidate the genetic pathways underlying the first described form of regulated cell death, apoptosis. Since then, C.
Marcos A. Perez, Jennifer L. Watts
doaj   +1 more source

Diannexin protects against renal ischemia reperfusion injury and targets phosphatidylserines in ischemic tissue. [PDF]

open access: yesPLoS ONE, 2011
Renal ischemia/reperfusion injury (IRI) frequently complicates shock, renal transplantation and cardiac and aortic surgery, and has prognostic significance. The translocation of phosphatidylserines to cell surfaces is an important pro-inflammatory signal
Kimberley E Wever   +7 more
doaj   +1 more source

Phosphatidylserine in atherosclerosis [PDF]

open access: yesCurrent Opinion in Lipidology, 2016
Purpose of review It is now widely acknowledged that phosphatidylserine is a multifunctional bioactive lipid. In this review, we focus on the function of phosphatidylserine in modulating cholesterol metabolism, influencing inflammatory response and regulating coagulation system, and discuss promising phosphatidylserine-based ...
Darabi, Maryam, Kontush, Anatol
openaire   +3 more sources

Identification of a broad lipid repertoire associated to the endothelial cell protein C receptor (EPCR)

open access: yesScientific Reports, 2022
Evidence is mounting that the nature of the lipid bound to the endothelial cell protein C receptor (EPCR) has an impact on its biological roles, as observed in anticoagulation and more recently, in autoimmune disease.
Elena Erausquin   +6 more
doaj   +1 more source

Effects of Natural Antioxidants on Phospholipid and Ceramide Profiles of 3D-Cultured Skin Fibroblasts Exposed to UVA or UVB Radiation

open access: yesAntioxidants, 2021
Ultraviolet (UV) radiation is one of the primary factors responsible for disturbances in human skin cells phospholipid metabolism. Natural compounds that are commonly used to protect skin, due to their lipophilic or hydrophilic nature, show only a narrow
Agnieszka Gęgotek   +2 more
doaj   +1 more source

Phosphatidylserine, a death knell [PDF]

open access: yesCell Death & Differentiation, 2001
Virtually every cell in the body restricts phosphatidylserine (PS) to the inner leaflet of the plasma membrane by energy-dependent transport from the outer to the inner leaflet of the bilayer. Apoptotic cells of all types rapidly randomize the asymmetric distribution, bringing PS to the surface where it serves as a signal for phagocytosis.
R A, Schlegel, P, Williamson
openaire   +2 more sources

Untargeted Lipidomics and Chemometric Tools for the Characterization and Discrimination of Irradiated Camembert Cheese Analyzed by UHPLC-Q-Orbitrap-MS

open access: yesFoods, 2023
In this work, an investigation using UHPLC-Q-Orbitrap-MS and multivariate statistics was conducted to obtain the lipid fingerprint of Camembert cheese and to explore its correlated variation with respect to X-ray irradiation treatment.
Michele Tomaiuolo   +5 more
doaj   +1 more source

Herpes simplex viruses activate phospholipid scramblase to redistribute phosphatidylserines and Akt to the outer leaflet of the plasma membrane and promote viral entry.

open access: yesPLoS Pathogens, 2018
Herpes simplex virus (HSV) entry is associated with Akt translocation to the outer leaflet of the plasma membrane to promote a complex signaling cascade.
Natalia Cheshenko   +2 more
doaj   +1 more source

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