Results 111 to 120 of about 52,049 (355)

Effect of exogenous phosphocreatine on the course of acute limb ischemia and reperfusion syndrome after arterial reconstruction in patients with vascular trauma

open access: yesМедицина неотложных состояний
Background. Acute limb ischemia caused by traumatic arterial injury remains one of the most challenging problems of emergency vascular surgery. Restoration of blood flow may paradoxically provoke ischemia-reperfusion injury leading to limb loss.
O.B. Kutovyi   +3 more
doaj   +1 more source

Exogenous Phosphocreatine Application in Elderly and Senile Patients Operated for Colorectal Cancer

open access: yesОбщая реаниматология, 2017
Objective: to evaluate the efficacy of exogenous phosphocreatine (EPCr) application in elderly and senile patients operated for colorectal cancer.Material and methods.
V. N. Derbugov   +3 more
doaj   +1 more source

Single and dual RPA‐CRISPR/Cas assays for point‐of‐need detection of Stewart's wilt pathogen (Pantoea stewartii subsp. stewartii) of corn and Maize dwarf mosaic virus

open access: yesPest Management Science, Volume 81, Issue 4, Page 1988-1999, April 2025.
Schematic diagram of the single and dual RPA‐CRISPR/Cas12a/13a diagnostic assays for the detection of Pantoea stewartii subsp. stewartii and Maize dwarf mosaic virus. The validated assays provide a useful and sensitive molecular tool for detecting two quarantine pathogens of maize within a minimal resource framework suitable for fast‐tracking the ...
Qian Tian   +6 more
wiley   +1 more source

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

open access: yesBritish Journal of Pharmacology, EarlyView.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez   +13 more
wiley   +1 more source

Analysis of creatine kinase activity with evaluation of protein expression under the effect of heat and hydrogen peroxide [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2015
Protein oxidation has detrimental effects on the brain functioning, which involves inhibition of the crucial enzyme, brain type creatine kinase (CKBB), responsible for the CK/phosphocreatine shuttle system. Here we demonstrate a susceptibility of CKBB to
A. D. Rakhmetov   +3 more
doaj  

Retention of differentiated properties in an established dog kidney epithelial cell line (MDCK). [PDF]

open access: yes, 1979
Madin-Darby canine kidney (MDCK) cells grown in tissue culture have the morphological properties of distal tubular epithelial cells, form tight junctions, and lack several proximal tubular enzyme markers.
Chuman, LM   +3 more
core  

Increased Adenine Nucleotide Degradation in Skeletal Muscle Atrophy [PDF]

open access: yes, 2019
Adenine nucleotides (AdNs: ATP, ADP, AMP) are essential biological compounds that facilitate many necessary cellular processes by providing chemical energy, mediating intracellular signaling, and regulating protein metabolism and solubilization.
Brault, Jeffrey J.   +2 more
core   +1 more source

Phosphocreatine in Red and White Muscle

open access: yesExperimental Biology and Medicine, 1951
ConclusionThe creatine phosphate content of the white breast muscle of the fowl was found to be over twice as great as that of the red leg muscle. In the “flying” bird, the pigeon, the red breast muscle and the leg muscle contained approximately the same levels of this high energy phosphate.
openaire   +2 more sources

The ALS‐associated E425K mutation uncouples DNAJC7 from the Hsp70 chaperone cycle

open access: yesThe FEBS Journal, EarlyView.
DNAJC7 is a J‐domain protein that plays a key role in protein quality control by regulating Hsp70 activity and preventing protein aggregation. We find that the ALS‐associated E425K mutation in DNAJC7 disrupts productive interaction and activation of Hsp70, thereby blocking the transfer and refolding of client proteins such as TDP‐43.
Bar Elmaleh   +2 more
wiley   +1 more source

The effectiveness of phosphocreatine cardioprotection during vascular surgery in high cardiac risk patients

open access: yesВестник анестезиологии и реаниматологии
The objective was to study the occurrence of perioperative cardiovascular complications (CVС) and clinical and laboratory cardioprotection signs in patients treated with phosphocreatine infusion in intraoperative period of vascular surgery.Materials and ...
I. A. Kozlov   +2 more
doaj   +1 more source

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