Results 131 to 140 of about 48,855 (331)
OBJECTIVE Recent studies identified the rs9939609 A-allele of the FTO (fat mass and obesity associated) gene as being associated with obesity and type 2 diabetes.
L. Grunnet+9 more
semanticscholar +1 more source
Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs+12 more
wiley +1 more source
Developmental sensory experience balances cortical excitation and inhibition. [PDF]
Early in life, neural circuits are highly susceptible to outside influences. The organization of the primary auditory cortex (A1) in particular is governed by acoustic experience during the critical period, an epoch near the beginning of postnatal ...
Barker, Alison J+4 more
core +3 more sources
Phosphocreatine as Energy Source of the Action Potential
The parallelism between the concentration of choline esterase and the E.M.F. of the action potential in electric organs and the localization of the enzyme at the neuronal surface suggest that formation of acetylcholine is intrinsically connected with the nerve action potential and may be responsible for the electrical changes during nerve activity ...
David Nachmansohn+4 more
openaire +2 more sources
The aim of the study was to evaluate the efficacy of lecithin/cholesterol liposomes in the therapy of experimental venous congestion-induced chronic liver insufficiency. The effects of the empty liposomes, ATP and phosphocreatine-containing liposomes and
R. A. Mukhamadiyarov+4 more
doaj +1 more source
Multi‐Omics Reveal the Metabolic Changes in Cumulus Cells During Aging
Fatty acid β‐oxidation was elevated in cumulus cells from older mice. Tryptophan metabolism in aged cumulus cells was active. Supplementing with 5‐HT could mitigate aging damage in oocytes. ABSTRACT Maternal age has been reported to impair oocyte quality.
Liangyue Shi+6 more
wiley +1 more source
ABSTRACT Despite its role in energy and amino acid (AA) metabolism, no work has investigated creatine (Cr) content in commercial cat food. This study evaluated the Cr, creatinine (CrN), crude protein (CP) and AA concentrations of 30 commercial extruded cat diets.
Taylor Richards+3 more
wiley +1 more source
Dopamine D-3 receptors regulate GABA(A) receptor function through a phospho-dependent endocytosis mechanism in nucleus accumbens [PDF]
The dopamine D-3 receptor, which is highly enriched in nucleus accumbens (NAc), has been suggested to play an important role in reinforcement and reward.
Chen, GJ, Kittler, JT, Moss, SJ, Yan, Z
core
Effects of creatine monohydrate supplementation on simulated soccer performance [PDF]
Purpose: To determine the effects of acute short-term creatine (Cr) supplementation on physical performance during a 90-min soccer-specific performance test. Methods: A double-blind, placebo-controlled experimental design was adopted during which 16 male
Abt, Grant+2 more
core +1 more source
THE DISTRIBUTION OF PHOSPHOARGININE AND PHOSPHOCREATINE IN MARINE INVERTEBRATES
1. The arginine, creatine, and related phosphagen content was determined in muscle-containing tissues of nine species of echinoderms, from four subphyla, and in one species of hemichordate. Similar determinations were made on the unfertilized ova of the starfish, Asterias forbesi, and of the two urchins, Arbacia punctata and Lytechinus variegatus.2 ...
openaire +4 more sources