Results 131 to 140 of about 48,855 (331)

Increased recovery rates of phosphocreatine and inorganic phosphate after isometric contraction in oxidative muscle fibers and elevated hepatic insulin resistance in homozygous carriers of the A-allele of FTO rs9939609.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2009
OBJECTIVE Recent studies identified the rs9939609 A-allele of the FTO (fat mass and obesity associated) gene as being associated with obesity and type 2 diabetes.
L. Grunnet   +9 more
semanticscholar   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

open access: yesActa Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs   +12 more
wiley   +1 more source

Developmental sensory experience balances cortical excitation and inhibition. [PDF]

open access: yes, 2010
Early in life, neural circuits are highly susceptible to outside influences. The organization of the primary auditory cortex (A1) in particular is governed by acoustic experience during the critical period, an epoch near the beginning of postnatal ...
Barker, Alison J   +4 more
core   +3 more sources

Phosphocreatine as Energy Source of the Action Potential

open access: yesExperimental Biology and Medicine, 1943
The parallelism between the concentration of choline esterase and the E.M.F. of the action potential in electric organs and the localization of the enzyme at the neuronal surface suggest that formation of acetylcholine is intrinsically connected with the nerve action potential and may be responsible for the electrical changes during nerve activity ...
David Nachmansohn   +4 more
openaire   +2 more sources

Comparative assessment of hepatoprotective effects of various liposome formulations in experimental venous congestion-induced chronic liver insufficiency

open access: yesБюллетень сибирской медицины, 2012
The aim of the study was to evaluate the efficacy of lecithin/cholesterol liposomes in the therapy of experimental venous congestion-induced chronic liver insufficiency. The effects of the empty liposomes, ATP and phosphocreatine-containing liposomes and
R. A. Mukhamadiyarov   +4 more
doaj   +1 more source

Multi‐Omics Reveal the Metabolic Changes in Cumulus Cells During Aging

open access: yesCell Proliferation, EarlyView.
Fatty acid β‐oxidation was elevated in cumulus cells from older mice. Tryptophan metabolism in aged cumulus cells was active. Supplementing with 5‐HT could mitigate aging damage in oocytes. ABSTRACT Maternal age has been reported to impair oocyte quality.
Liangyue Shi   +6 more
wiley   +1 more source

A Comparative Analysis of Creatine, Creatinine, Amino Acid Concentrations and Indispensable Amino Acid Scores of Grain‐Free and Grain‐Inclusive Commercial Extruded Adult Cat Foods

open access: yesJournal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Despite its role in energy and amino acid (AA) metabolism, no work has investigated creatine (Cr) content in commercial cat food. This study evaluated the Cr, creatinine (CrN), crude protein (CP) and AA concentrations of 30 commercial extruded cat diets.
Taylor Richards   +3 more
wiley   +1 more source

Dopamine D-3 receptors regulate GABA(A) receptor function through a phospho-dependent endocytosis mechanism in nucleus accumbens [PDF]

open access: yes, 2006
The dopamine D-3 receptor, which is highly enriched in nucleus accumbens (NAc), has been suggested to play an important role in reinforcement and reward.
Chen, GJ, Kittler, JT, Moss, SJ, Yan, Z
core  

Effects of creatine monohydrate supplementation on simulated soccer performance [PDF]

open access: yes, 2014
Purpose: To determine the effects of acute short-term creatine (Cr) supplementation on physical performance during a 90-min soccer-specific performance test. Methods: A double-blind, placebo-controlled experimental design was adopted during which 16 male
Abt, Grant   +2 more
core   +1 more source

THE DISTRIBUTION OF PHOSPHOARGININE AND PHOSPHOCREATINE IN MARINE INVERTEBRATES

open access: yesThe Biological Bulletin, 1971
1. The arginine, creatine, and related phosphagen content was determined in muscle-containing tissues of nine species of echinoderms, from four subphyla, and in one species of hemichordate. Similar determinations were made on the unfertilized ova of the starfish, Asterias forbesi, and of the two urchins, Arbacia punctata and Lytechinus variegatus.2 ...
openaire   +4 more sources

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