Results 71 to 80 of about 48,855 (331)

Diagnostic Accuracy of ¹H-MRS Using PRESS and MEGA-PRESS Techniques in the Preoperative Grading of Patients With Gliomas. [PDF]

J Magn Reson Imaging
Background Edited MRS technique such as MEshcher‐GArwood Point RESolved Spectroscopy (MEGA‐PRESS) can determine isocitrate dehydrogenase mutation (IDH) mutation status in patients with gliomas but its accuracy in assessing glioma grade has not yet been formally evaluated.
Brun-Vergara ML, Melkus G, Chakraborty S, Zakhari N, Torres C, AlKherayf F, Ghantous L, Thornhill R, Woulfe J, Jansen GH, Nguyen TB.   +10 more
europepmc   +2 more sources

Detection of Metabolites by Proton Ex Vivo NMR, in Vivo MR Spectroscopy Peaks and Tissue Content Analysis: Biochemical-Magnetic Resonance Correlation: Preliminary Results [PDF]

, 2009
*Aim*: Metabolite concentrations by in vivo magnetic resonance spectroscopy and ex vivo NMR spectroscopy were compared with excised normal human tissue relaxation times and tissue homogenate contents. *Hypothesis*: Biochemical analysis
Arun Agrawala, Madan Rehani, Rakesh Sharma   +2 more
core   +1 more source

Risk Factors and Predictive Models for Sarcopenia in Older Adults

AGING MEDICINE, EarlyView.
Independent risk factors for sarcopenia identified by Lasso regression and logistic regression in the study were BMI, prealbumin, albumin/globulin ratio (A/G ratio), serum creatinine, and phosphorus. These factors were used to construct a nomogram model and a decision tree model. Both models showed effectiveness in predicting sarcopenia in older adults,
Shiyuan Zhang, Xue Yang, Nina An, Meng Lv, Lanyu Yang, Rui Liu, Song Hu, Weiguo Chen, Wenjing Feng, Yongjun Mao   +9 more
wiley   +1 more source

Myocardial inflammation is associated with impaired mitochondrial oxidative capacity in ischaemic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1246-1255, April 2025.
Abstract Aims Myocardial inflammation and impaired mitochondrial oxidative capacity are hallmarks of heart failure (HF) pathophysiology. The extent of myocardial inflammation in patients suffering from ischaemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM) and its association with mitochondrial energy metabolism are unknown.
Julius Borger, Elric Zweck, Constanze Moos, Patrick Horn, Fabian Voß, Heinz‐Peter Schultheiss, Jacob Eifer Møller, Udo Boeken, Hug Aubin, Artur Lichtenberg, Malte Kelm, Michael Roden, Amin Polzin, Ralf Westenfeld, Julia Szendroedi, Daniel Scheiber   +15 more
wiley   +1 more source

IRES-mediated Pichia pastoris cell-free protein synthesis

Bioresources and Bioprocessing, 2023
Cell-free protein synthesis (CFPS) system is an ideal platform for fast and convenient protein research and has been used for macromolecular assembly, unnatural amino acid embedding, glycoprotein production, and more.
Yanan Wang, Ting Wang, Xinjie Chen, Yuan Lu   +3 more
doaj   +1 more source

Advanced phosphocreatine-grafted chitosan hydrogel promote wound healing by macrophage modulation

Frontiers in Bioengineering and Biotechnology, 2023
Background: The repair of wounds usually caused by trauma or other chronic diseases remained challenging in clinics due to the potential risk of inflammation and inadequate tissue regenerative properties.
Weibei Sheng, Haotian Qin, Tiehua Wang, Jin Zhao, Chongzhou Fang, Peng Zhang, Peng Liu, Anjaneyulu Udduttula, Hui Zeng, Yingqi Chen   +9 more
doaj   +1 more source

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

Coil Combination Using OpTIMUS Results in Improved Signal-to-Noise Ratios of In Vivo MR Spectra Acquired at 7 T. [PDF]

NMR Biomed
Coil combination with OpTIMUS increases SNR of MR spectra at 7 T compared to well‐established coil combination algorithms without compromising spectral quantification. By reducing spectral noise and incorporating the metabolic signal from higher order singular vectors, OpTIMUS has the potential to enable shorter acquisition times compared to the ...
Martinez Luque E, Sung D, Risk BB, Goldberg RM, Fleischer CC.   +4 more
europepmc   +2 more sources

Cognitive-behavioral therapy for obsessive-compulsive disorder: access to treatment, prediction of long-term outcome with neuroimaging. [PDF]

, 2015
This article reviews issues related to a major challenge to the field for obsessive-compulsive disorder (OCD): improving access to cognitive-behavioral therapy (CBT).
Feusner, Jamie D, O'Neill, Joseph
core   +2 more sources

Lower Mitochondrial Energy Production of the Thigh Muscles in Patients With Low‐Normal Ankle‐Brachial Index

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundLower muscle mitochondrial energy production may contribute to impaired walking endurance in patients with peripheral arterial disease. A borderline ankle‐brachial index (ABI) of 0.91 to 1.10 is associated with poorer walking endurance compared
Majd AlGhatrif, Ariel Zane, Matt Oberdier, Marco Canepa, Stephanie Studenski, Eleanor Simonsick, Richard G. Spencer, Kenneth Fishbein, David Reiter, Edward G. Lakatta, Mary M. McDermott, Luigi Ferrucci   +11 more
doaj   +1 more source