Results 131 to 140 of about 12,220,634 (288)

Protective Effects of Riociguat Against Contrast‐Induced Nephropathy: An Experimental and Machine Learning‐Based Study in Rats

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Contrast‐induced nephropathy (CIN) is an important cause of acute kidney injury following exposure to iodinated contrast media, and effective preventive strategies remain limited. This study investigated the renoprotective effects of riociguat, a soluble guanylate cyclase stimulator, in an experimental rat model of CIN and explored machine ...
Mustafa Begenc Tascanov, Kenan Toprak, Sibel Turedi, İsmail Koyuncu, Zulkif Tanrıverdi, Necip Fazıl Dedeoglu, Halil Fedai, Asuman Bicer, İbrahim Halil Altıparmak, Recep Demirbag, Gencay Sarıısık   +10 more
wiley   +1 more source

Bacillus subtilis Mobilizes Phosphorus by Reshaping P Pools, Sorption, and Enzyme Activities

Land Degradation &Development, EarlyView.
ABSTRACT Low phosphorus (P) availability constrains crop production in saline‐alkaline soils of Xinjiang, China. We tested whether Bacillus subtilis (B. subtilis) mobilizes soil P by altering P fractions, sorption–desorption, and P‐cycling enzymes in a saline‐alkaline cotton soil. Under conventional fertilization, B. subtilis was applied at 0 (B0), 15 (
Haiping Xie, Wenbin Deng, Yiming Zhao, Rongjiang Yao, Guangming Liu, Jinlin Chen   +5 more
wiley   +1 more source

Phosphodiesterase Type 5 Inhibitors as Chemical Hazards in Honey and Honey-Based Products

Molecules
The processing of bee products has recently become more frequent due to the rapidly growing market and demand for healthy, natural, and functional food. Therefore, bee products, and above all honey, while maintaining the reputation of healthy and natural
Joanna Wojtacka
doaj   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Phosphodiesterase type 5 inhibitors as treatment for erectile dysfunction: a webinar-based poll unveiling perceptions of healthcare professionals

Journal of Comparative Effectiveness Research
Aim: Erectile dysfunction (ED) is marked by a recurring incapacity to achieve or uphold a satisfactory erection during sexual activities. The study aims to increase awareness about male reproductive health, dispel misconceptions about ED and encourage ...
Maher S Moazin, Abdulaziz Baazeem, Ayman Al-Bakri, Adel Al Dayel, Ashraf Amir, Saud Al Sifri, Mona Reda, Fahad Bashraheel, Abdullah Alfakhri, Yousef Hamdy, Fayez Elshaer   +10 more
doaj   +1 more source

Use of Phosphodiesterase Type 5 Inhibitors for Erectile Dysfunction and Risk of Malignant Melanoma.

, 2015
The target for the oral erectile dysfunction drugs, phosphodiesterase type 5 (PDE5) inhibitors, is part of a pathway implicated in the development of malignant melanoma.
Robinson, David,, Folkvaljon, Yasin, Stattin, Pär, Lambe, Mats, Stattin, Pär,, Garmo, Hans, Loeb, Stacy, Robinson, David, Ingvar, Christian,, Lund University., Ingvar, Christian   +10 more
core   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Use of phosphodiesterase-5 inhibitors by college students.

Revista de saude publica, 2008
El objetivo del estudio fue identificar el uso de inhibidores de la fosfodiesterasa-5 por estudiantes universitarios de la ciudad de Sao Paulo (SP), en 2006. Alumnos del sexo masculino (n=360) respondieron un cuestionario sobre el diagnóstico de disfunción eréctil, frecuencia e motivo del uso, medicamento utilizado, existencia de prescripción medica y ...
Freitas, Vanessa Mello de, Menezes, Fabiana Gatti de, Antonialli, Michele Melo Silva, Nascimento, Jorge Willian Leandro   +3 more
openaire   +2 more sources

Characterization of cyclic nucleotide phosphodiesterase isoenzymes in the human ureter and their functional role in vitro [PDF]

, 1994
Meyer, M. F., Schulz-Knappe, P., Forssmann, W. G., Stief, Christian Georg, Taher, A., Jonas, Udo, Truss, Michael C., C.G. Stief, A. Taher, P. Schulz-Knappe, M. Meyer, U. Jonas, M. Truss, W.-G. Forssmann   +13 more
core   +1 more source

The Benefits of Adding Non‐Antimuscarinic Pharmaceuticals in Combination With Beta‐3 Agonists for Overactive Bladder Treatment: A Systematic Review

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Antimuscarinics, as the current first‐line pharmacologic therapies for overactive bladder, exhibit low patient adherence and high rates of reported side effects. As a modern alternative pharmaceutical treatment, beta‐3 agonists, which relax the urinary bladder, may be more tolerable for patients, increasing adherence and ...
Felicity Smith, Charlotte Phelps, Christian Moro   +2 more
wiley   +1 more source