Results 121 to 130 of about 79,270 (300)

Management of erectile dysfunction with a novel orodispersible formulation of the PDE-5 inhibitor vardenafil [PDF]

open access: yes, 2011
Erectile dysfunction (ED) is a medical condition which can affect men of all ages. As men live longer and the prevalence of cardiovascular disease and diabetes continue to increase, the problem of ED will become more prominent.
Cordina, Maria
core  

Counterfeit phosphodiesterase type 5 inhibitors pose significant safety risks.

open access: yesInternational journal of clinical practice, 2010
Counterfeit drugs are inherently dangerous and a growing problem; counterfeiters are becoming increasingly sophisticated. Growth of the counterfeit medication market is attributable in part to phosphodiesterase type 5 inhibitor (PDE5i) medications for erectile dysfunction (ED).
Jackson, G   +3 more
openaire   +2 more sources

Post Activation Potentiation Is Greater in Human Triceps Brachii Versus Triceps Surae Muscles

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Voluntary muscle contractions result in a temporary increase in twitch force, a phenomenon termed post activation potentiation (PAP). In rodents and other species, PAP is observed predominantly or exclusively in fast twitch muscles. However, it has been suggested that in humans, PAP occurs more or less independently of muscle
William S. Zoughaib   +4 more
wiley   +1 more source

Safety and tolerability considerations in the use of sildenafil for children with pulmonary arterial hypertension

open access: yesDrug, Healthcare and Patient Safety, 2015
Andrew L Dodgen,1 Kevin D Hill1,2 1Department of Pediatrics, Duke University Medical Center, 2Duke Clinical Research Institute, Durham, NC, USA Abstract: Sildenafil is a phosphodiesterase type-5 inhibitor approved for treatment of pulmonary arterial ...
Dodgen AL, Hill KD
doaj  

Tadalafil therapy for erectile dysfunction following prostatectomy

open access: yesTherapeutic Advances in Urology, 2015
Erectile dysfunction is a major complication affecting the quality of life of patients and partners after radical prostatectomy. Evolving evidence suggests that early penile rehabilitation may provide better erectile function after surgery ...
Ateş Kadıoğlu   +3 more
doaj   +1 more source

Phosphodiesterase Type-5 Inhibitor Tadalafil Modulates Steroid Hormones Signaling in a Prostate Cancer Cell Line. [PDF]

open access: yesInt J Mol Sci, 2021
Bimonte VM   +11 more
europepmc   +1 more source

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

open access: yesRheumatology &Autoimmunity, EarlyView.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

Tadalafil in the treatment of erectile dysfunction

open access: yesTherapeutics and Clinical Risk Management, 2008
Robert M Coward, Culley C CarsonDivision of Urologic Surgery, University of North Carolina, Chapel Hill, NC, USAAbstract: The treatment for erectile dysfunction (ED) was revolutionized with the development of phosphodiesterase type 5 (PDE5) inhibitors ...
Robert M Coward, Culley C Carson
doaj  

Sympatho‐Excitation in Pulmonary Hypertension: The Potential Role of Pulmonary Arterial Baroreceptors: An Acute Physiologic Intervention Study

open access: yesRespirology, EarlyView.
Pulmonary arterial baroreceptors reflexively stimulate sympathetic nerve activity (SNA) in response to elevated pulmonary artery pressure and distension. In pulmonary hypertension patients, changes in muscle SNA were proportional to changes in pulmonary haemodynamics following nebulised iloprost.
Michael J. Plunkett   +6 more
wiley   +1 more source

Update on the clinical utility of sildenafil in the treatment of pulmonary arterial hypertension

open access: yesDrug Design, Development and Therapy, 2010
Gautam V Ramani, Myung H ParkUniversity of Maryland, Baltimore, MD, USAAbstract: Sildenafil is an orally administered phosphodiesterase type 5 inhibitor that is approved for the treatment of pulmonary arterial hypertension (PAH).
Gautam V Ramani, Myung H Park
doaj  

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