Results 21 to 30 of about 28,180 (258)

The Role of Cysteine Residues in Catalysis of Phosphoenolpyruvate Carboxykinase from Mycobacterium tuberculosis. [PDF]

open access: yesPLoS ONE, 2017
Mycobacterium tuberculosis (MTb), the causative agent of tuberculosis, can persist in macrophages for decades, maintaining its basic metabolic activities.
Iva Machová   +8 more
doaj   +2 more sources

Phosphoenolpyruvate carboxykinase. II. Hormonal controls

open access: bronzeThe American Journal of Clinical Nutrition, 1973
Richard W. Hanson   +3 more
openalex   +4 more sources

Peculiarities of the relationship between the terminal site of glycolysis and the initial segment of gluconeogenesis in the myocardium and skeletal muscles of animals irradiated at different doses

open access: yesJournal of Education, Health and Sport, 2023
Existing types of muscles differ not only structurally, but also metabolically (direction of energy exchange, choice of biosubstrates, dependence on the action of mediators, hormones, etc.).
G. Stepanov   +3 more
doaj   +1 more source

The possible role of Phosphoenolpyrovate Carboxykinase (PEPCKin protein content of chickpea seeds (Cicer arietinum L [PDF]

open access: yesپژوهش‌های حبوبات ایران, 2010
Phosphoenolpyruvate Carboxykinase (PEPCK) has been shown to be present in plants andanimals, playing different metabolic roles in different tissues. The basic role of this enzyme is itscontribution in the gluconeogenesis pathway.
Maria Beihaghi   +4 more
doaj   +1 more source

Genetic variability in exon 9 of PEPCK-M gene in different strains of chickens using PCR-RFLP method [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2015
Phosphoenolpyruvate carboxykinase (PEPCK) catalyzes the first step of the gluconeogenesis cycle. There are two isozymes forms of this enzyme, cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C) and mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-
Zohreh Yousefi   +2 more
doaj   +1 more source

O-GlcNAcylated p53 in the liver modulates hepatic glucose production

open access: yesNature Communications, 2021
p53 regulates signalling pathways involved in metabolic homeostasis. Here the authors show that O-GlcNAcylation of p53 in the liver plays a key role in the physiological regulation of glucose homeostasis, potentially via controlling the expression of the
Maria J. Gonzalez-Rellan   +42 more
doaj   +1 more source

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

open access: yesHepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro   +14 more
wiley   +1 more source

Phosphoenolpyruvate carboxykinase deficiency [PDF]

open access: yesPediatric Research, 1974
Inborn errors of 3 of the 4 enzymes specific for gluconeogenesis are known. The present report describes a deficiency of the 4th enzyme phosphoenolpyruvate carboxykinase (PEP-CK). characterized by severe hypoglycemia and extreme fatty changes of liver and kidney.
F A Hommes, J D Elema, C Bendien
openaire   +2 more sources

Millisecond mix-and-quench crystallography (MMQX) enables time-resolved studies of PEPCK with remote data collection

open access: yesIUCrJ, 2021
Time-resolved crystallography of biomolecules in action has advanced rapidly as methods for serial crystallography have improved, but the large number of crystals and the complex experimental infrastructure that are required remain serious obstacles to ...
Jonathan A. Clinger   +4 more
doaj   +1 more source

Deficiency of gluconeogenic enzyme PCK1 promotes metabolic-associated fatty liver disease through PI3K/AKT/PDGF axis activation in male mice

open access: yesNature Communications, 2023
Phosphoenolpyruvate carboxykinase 1 (Pck1) is an enzyme involved in glucose production that also regulates lipogenesis and has been linked to liver steatosis.
Qian Ye   +13 more
doaj   +1 more source

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