Journal of Education, Health and Sport, 2023 Existing types of muscles differ not only structurally, but also metabolically (direction of energy exchange, choice of biosubstrates, dependence on the action of mediators, hormones, etc.).
G. Stepanov +3 more
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Mitochondrial phosphoenolpyruvate carboxykinase inhibits kidney renal clear cell carcinoma malignant progression, leading to cell energy metabolism imbalance. [PDF]
Am J Cancer Res, 2023 Chen Y, Wang Z, Deng Q, Chen Y, Liang H.
europepmc +2 more sources
The possible role of Phosphoenolpyrovate Carboxykinase (PEPCKin protein content of chickpea seeds (Cicer arietinum L [PDF]
پژوهشهای حبوبات ایران, 2010 Phosphoenolpyruvate Carboxykinase (PEPCK) has been shown to be present in plants andanimals, playing different metabolic roles in different tissues. The basic role of this enzyme is itscontribution in the gluconeogenesis pathway.
Maria Beihaghi +4 more
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Protective effect of phosphoenolpyruvate carboxykinase 1 on inflammation and fibrotic progression of IgA nephropathy. [PDF]
Ren FailTan YY +6 more
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Genetic variability in exon 9 of PEPCK-M gene in different strains of chickens using PCR-RFLP method [PDF]
مجله بیوتکنولوژی کشاورزی, 2015 Phosphoenolpyruvate carboxykinase (PEPCK) catalyzes the first step of the gluconeogenesis cycle. There are two isozymes forms of this enzyme, cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C) and mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-
Zohreh Yousefi +2 more
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The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Hepatology, EarlyView., 2022 Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro +14 more
wiley +1 more source
O-GlcNAcylated p53 in the liver modulates hepatic glucose production
Nature Communications, 2021 p53 regulates signalling pathways involved in metabolic homeostasis. Here the authors show that O-GlcNAcylation of p53 in the liver plays a key role in the physiological regulation of glucose homeostasis, potentially via controlling the expression of the
Maria J. Gonzalez-Rellan +42 more
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IUCrJ, 2021 Time-resolved crystallography of biomolecules in action has advanced rapidly as methods for serial crystallography have improved, but the large number of crystals and the complex experimental infrastructure that are required remain serious obstacles to ...
Jonathan A. Clinger +4 more
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Phosphoenolpyruvate carboxykinase deficiency [PDF]
Pediatric Research, 1974 Inborn errors of 3 of the 4 enzymes specific for gluconeogenesis are known. The present report describes a deficiency of the 4th enzyme phosphoenolpyruvate carboxykinase (PEP-CK). characterized by severe hypoglycemia and extreme fatty changes of liver and kidney.
F A Hommes, C Bendien, J D Elema
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Biological Evaluation of a Mitochondrial Phosphoenolpyruvate Carboxykinase Inhibitor
Proceedings, 2019 Phosphoenolpyruvate carboxykinase (PEPCK) is a key enzyme in gluconeogenesis, catalyzingthe decarboxylation of oxaloacetate to phosphoenolpyruvate. [...]
Sergio Rodríguez-Arévalo +9 more
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